Results 251 to 260 of about 39,485 (293)

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

SARS-CoV‑2 RNA's Dual Identity: G‑Quadruplex versus Hairpin. [PDF]

ACS Omega
Nyporko A, Voiteshenko I, Zarudnaya M, Hurmach V, Shyryna T, Platonov M, Roszak S, Rasulev B, Gorb L.   +8 more
europepmc   +1 more source

Lewis Pair‐Engineered CuMnOx as Cold‐Adapted Multinanozyme for Cooperative Hydrolytic and Oxidative Degradation of Raw Corn Stalk

Advanced Science, EarlyView.
A Lewis pair site design strategy was established to construct Cu‐doped Mn‐based amorphous nanozymes, where Mn and oxygen vacancies generate cooperative acid‐base pairs. The resulting multinanozyme integrates glycosidase‐, oxidase‐, and cold‐adapted enzyme‐mimicking activities, enabling cooperative depolymerization of cellulose and hemicellulose ...
Huile Liu, Ziyi Di, Qing Tian, Yue Zhou, Rong Yang, Zhiyi Bai, Haoyu Wang, Yao Chen, Lianbing Zhang   +8 more
wiley   +1 more source

Combining Cyclic Triimidazo Triazine Core With Ethynyl-N-Methyl-Pyridinium Groups for Targeting G-Quadruplex Structures. [PDF]

Arch Pharm (Weinheim)
Platella C, Di Ciolo S, Criscuolo A, Malpicci D, Gaglione R, Arciello A, Musumeci D, Lucenti E, Cariati E, Montesarchio D, Giannini C.   +10 more
europepmc   +1 more source

Paradoxical G-quadruplex distribution in coronavirus genomes reveals functional constraints and antiviral therapeutic opportunities. [PDF]

Virus Res
Tanigawa M, Iwaki T.
europepmc   +1 more source

Towards improved anticancer properties of the G-quadruplex-forming T40231 aptamer through increased flexibility of nucleoside residues. [PDF]

Sci Rep
Kotkowiak W, Bartyś N, Pasternak A.
europepmc   +1 more source

The quadruplex fluorescent quantitative PCR method for the simultaneous detection of respiratory diseases in quail: <i>Pasteurella multocida</i>, <i>Avibacterium paragallinarum</i>, <i>Mycoplasma gallisepticum</i>, and <i>Mycoplasma synoviae</i>. [PDF]

Front Microbiol
Wang H, Xue L, Wang L, Liu Y, Chen J, Sun Y, An T, Li C, Chen H, Yu C, Xia C, Zhang H.   +11 more
europepmc   +1 more source

Cation-Controlled Assembly, Activity, and Organization of Biomimetic DNA Receptors in Synthetic Cell Membranes. [PDF]

J Am Chem Soc
Peters E, Tanase DA, Di Michele L, Rubio-Sánchez R.   +3 more
europepmc   +1 more source

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Quadruplex World

Origins of Life and Evolution of Biospheres, 2021
The RNA world hypothesis relies on the double-helix complementarity principle for both replication and catalytic activity of RNA. However, the de novo appearance of the complementarity rules, without previous evolution steps, is doubtful. Another major problem of the RNA world is its isolated nature, making it almost impossible to accommodate the ...
openaire   +2 more sources