Results 71 to 80 of about 17,861,189 (258)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Cost effectiveness of bevacizumab plus carboplatin paclitaxel versus carboplatin paclitaxel as front line for advanced ovarian cancer in Thailand

Scientific Reports
Bevacizumab (BEV) combined with standard chemotherapy with carboplatin and paclitaxel (CP) as the front-line treatment for newly diagnosed advanced-stage epithelial ovarian cancer (EOC) is a promising treatment option.
Kanyarat Katanyoo, Usa Chaikledkaew, Nutthaporn Chandeying   +2 more
doaj   +1 more source

Health-adjusted life expectancy of the British population [PDF]

, 2008
In this article, changes in the quality of health-adjusted life expectancy of the British population between 1991 and 1998 are analysed. It is found that at all given age levels, life expectancy increased during this period.
Groot, W., Groot, Wim, van den Brink, H.M., Maassen van den Brink, Henriette, Maassen van den Brink, H., Groot, W.N.J., H. M. van den Brink, W. Groot   +7 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Methods for the estimation of the National Institute for Health and Care Excellence cost-effectiveness threshold

Health Technology Assessment, 2015
Background: Cost-effectiveness analysis involves the comparison of the incremental cost-effectiveness ratio of a new technology, which is more costly than existing alternatives, with the cost-effectiveness threshold.
Karl Claxton, Steve Martin, Marta Soares, Nigel Rice, Eldon Spackman, Sebastian Hinde, Nancy Devlin, Peter C Smith, Mark Sculpher   +8 more
doaj   +1 more source

Willingness to pay per quality-adjusted life year per gross domestic product per capita by country.

Willingness to pay per quality-adjusted life year per gross domestic product per capita by country.
Klas Göran Sahlen (17935584), Lars Lindholm (21685), Anh Nu Vu (17935581), Minh Van Hoang (6842081), Cuc Thi Thu Nguyen (14059662), Sun Sun (15469762)   +5 more
core   +1 more source

Comparison of the Quality of Life between Patients with Non-Small-Cell Lung Cancer and Healthy Controls

, 2012
We explored covariates of the quality of life (QOL) in non- small-cell lung cancer (NSCLC) patients and made a comparison with healthy controls. We assessed the QOL of 220 consecutive NSCLC patients at a university hospital. The QOL data were measured by
李俊賢;張郁瑩;李元麒;楊志新;劉紹興;劉邦祥;王榮德, LEE, LUKAS JYUHN-HSIARN;CHANG, YU-YIN;LEE, YUNG-CHIE;YANG, CHIH-HSIN;LIOU, SAOU-HSING;LIU, PANG-HSIANG;WANG, JUNG-DER   +1 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Global economic differences in modern glioblastoma care – a systematic review

Acta Neurochirurgica
Purpose Glioblastoma (GBM) is the most aggressive form of primary brain cancer and is associated with poor overall survival and expensive, resource intensive treatments.
Reuben Christopher, Livia Stauner, Mathias Spendel, Arwin Rezai, Alexander Romagna, Christoph Schwartz   +5 more
doaj   +1 more source

Assessment of cost-effectiveness threshold using a double-bounded dichotomous choice model

Public Health in Practice
Objectives: Willingness to pay (WTP) for one quality-adjusted life year (QALY) is highly variable according to survey methodology and can change over time, even within the same population.
Taito Kitano, Shinya Tsuzuki
doaj   +1 more source