A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Erratum to: A qualitative study of perceived needs and factors associated with the quality of care for common mental disorders in patients with chronic diseases: the perspective of primary care clinicians and patients [PDF]
Pasquale Roberge +17 more
openalex +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
Service Quality - Determining Factors
The goal of the paper is to present the development of social service system in Lithuania. The first period is from 1990 to 1998. It is stated that the first period is characterized by the rapid increase in the amount of social services. The second period started in 1998 and its distinguishing characteristic is an attention to the quality of social ...
openaire +3 more sources
Semidefinite and sum-of-squares (SOS) optimization are fundamental computational tools in many areas, including linear and nonlinear systems theory. However, the scale of problems that can be addressed reliably and efficiently is still limited.
Papachristodoulou, Antonis +2 more
core
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Impact of a Fruit and Vegetable Prescription Program on Diet Quality and Cardio-Metabolic Risk Factors in Healthy Adults in a Worksite Setting: A Randomized Controlled Trial (OR16-07-19) [PDF]
Beth Comerford +6 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Factors Affecting Quality of Life and Longevity in the Elderly People in Phrae City, Thailand.
Laddawan Daengthern +4 more
openalex +2 more sources

