Results 11 to 20 of about 25,949 (265)
Frontiers in Aging Neuroscience, 2021 The antidepressant drug amitriptyline is used in the treatment of clinical depression and a variety of neurological conditions such as anxiety, neuropathic pain disorders and migraine.
Eunyoung Bang +6 more
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Frontiers in Synaptic Neuroscience, 2020 Synaptic transmission between neurons is the basic mechanism for information processing in cortical microcircuits. To date, paired recording from synaptically coupled neurons is the most widely used method which allows a detailed functional ...
Guanxiao Qi +5 more
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Scientific Reports, 2023 A miniature postsynaptic current (mPSC) is a small, rare, and highly variable spontaneous synaptic event that is generally caused by the spontaneous release of single vesicles.
Susanna Gordleeva +3 more
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Quantal-Classical Duality and the Semiclassical Trace Formula [PDF]
, 1997 We consider Hamiltonian systems which can be described both classically and quantum mechanically. Trace formulas establish links between the energy spectra of the quantum description and the spectrum of actions of periodic orbits in the classical ...
Andersson +42 more
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Model-Based Inference of Synaptic Transmission
Frontiers in Synaptic Neuroscience, 2019 Synaptic computation is believed to underlie many forms of animal behavior. A correct identification of synaptic transmission properties is thus crucial for a better understanding of how the brain processes information, stores memories and learns ...
Ola Bykowska +12 more
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Multiquantal release underlies the distribution of synaptic efficacies in the neocortex
Frontiers in Computational Neuroscience, 2009 Inter-pyramidal synaptic connections are characterized by a wide range of EPSP amplitudes. Although repeatedly observed at different brain regions and across layers, little is known about the synaptic characteristics that contribute to this wide range ...
Alex Loebel +5 more
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What We Can Learn From Cumulative Numbers of Vesicular Release Events
Frontiers in Cellular Neuroscience, 2019 Following action potential invasion in presynaptic terminals, synaptic vesicles are released in a stochastic manner at release sites (docking sites). Since neurotransmission occurs at frequencies up to 1 kHz, the mechanisms underlying consecutive vesicle
Takafumi Miki
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Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex
Frontiers in Synaptic Neuroscience, 2019 Previous studies based on the ‘Quantal Model’ for synaptic transmission suggest that neurotransmitter release is mediated by a single release site at individual synaptic contacts in the neocortex.
Natalí Barros-Zulaica +7 more
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Quantal analysis based on density estimation
Journal of Neuroscience Methods, 2003 When direct measurements of the quantal parameters for a synapse cannot be made, these parameters can be extracted from an analysis of the fluctuations in the evoked response at that synapse. In this article, a decision tree is described in which the ability of the data to match simple models of quantal transmission is rigorously compared with its ...
Stricker, Christian, Redman, Stephen
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An explanation of anomalous behavior in models of political participation [PDF]
, 2005 This paper characterizes behavior with “noisy” decision making for models of political interaction characterized by simultaneous binary decisions. Applications include: voting participation games, candidate entry, the volunteer's dilemma, and collective ...
Goeree, Jacob K., Holt, Charles A.
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