Results 31 to 40 of about 26,062 (284)

A Complete Analysis on the Risk of Using Quantal Response: When Attacker Maliciously Changes Behavior under Uncertainty

open access: yesGames, 2022
In security games, the defender often has to predict the attacker’s behavior based on some observed attack data. However, a clever attacker can intentionally change its behavior to mislead the defender’s learning, leading to an ineffective defense ...
Thanh Hong Nguyen, Amulya Yadav
doaj   +1 more source

Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction [PDF]

open access: yes, 2017
Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells.
Bertone Cueto, Nicolás Iván   +5 more
core   +1 more source

Coexistence of planar and aplanar rotations in 195Tl

open access: yesPhysics Letters B, 2020
The chirality suggested for the doublet bands B2 and B2a in 195Tl in A∼190 region is reexamined. The potential-energy curves and the configurations together with the deformation parameters are obtained by the constrained covariant density functional ...
J. Peng, Q.B. Chen
doaj   +1 more source

PIEZO1 and the mechanism of the long circulatory longevity of human red blood cells.

open access: yesPLoS Computational Biology, 2021
Human red blood cells (RBCs) have a circulatory lifespan of about four months. Under constant oxidative and mechanical stress, but devoid of organelles and deprived of biosynthetic capacity for protein renewal, RBCs undergo substantial homeostatic ...
Simon Rogers, Virgilio L Lew
doaj   +1 more source

Variability in the Munc13-1 content of excitatory release sites

open access: yeseLife, 2021
The molecular mechanisms underlying the diversity of cortical glutamatergic synapses are still incompletely understood. Here, we tested the hypothesis that presynaptic active zones (AZs) are constructed from molecularly uniform, independent release sites
Maria Rita Karlocai   +5 more
doaj   +1 more source

Algebraic approach in the study of time-dependent nonlinear integrable systems: Case of the singular oscillator

open access: yes, 2000
The classical and the quantal problem of a particle interacting in one-dimension with an external time-dependent quadratic potential and a constant inverse square potential is studied from the Lie-algebraic point of view. The integrability of this system
A. de Sonza Dutra   +40 more
core   +1 more source

Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple synapses in situ

open access: yesNature Communications, 2019
How neurotransmitter release relates to presynaptic calcium dynamics is not fully understood. Here the authors develop an approach based on FLIM and optical quantal analysis for simultaneous imaging of calcium dynamics and glutamate release at ...
Thomas P. Jensen   +5 more
doaj   +1 more source

Neuromuscular recovery from botulism involves multiple forms of compensatory plasticity

open access: yesFrontiers in Cellular Neuroscience, 2023
IntroductionBotulinum neurotoxin (BoNT) causes neuroparalytic disease and death by blocking neuromuscular transmission. There are no specific therapies for clinical botulism and the only treatment option is supportive care until neuromuscular function ...
James B. Machamer   +9 more
doaj   +1 more source

A self-consistent quantal description of high-K states in the tilted-axis cranking model [PDF]

open access: yes, 2001
A self-consistent and quantal description of high-$K$ bands is given in the framework of the tilted-axis cranking model. (With a $\theta=90^{\circ}$ tilt angle with respect to $x$-axis, this cranking model is equivalent to the $z$-axis cranking.) The ...
Ahmad Ansari   +24 more
core   +2 more sources

Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses

open access: yeseLife, 2022
Ribbon synapses of cochlear inner hair cells (IHCs) are specialized to indefatigably transmit sound information at high rates. To understand the underlying mechanisms, structure-function analysis of the active zone (AZ) of these synapses is essential ...
Rituparna Chakrabarti   +15 more
doaj   +1 more source

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