Results 11 to 20 of about 26,062 (284)

Quantal analysis based on density estimation

Journal of Neuroscience Methods, 2003
When direct measurements of the quantal parameters for a synapse cannot be made, these parameters can be extracted from an analysis of the fluctuations in the evoked response at that synapse. In this article, a decision tree is described in which the ability of the data to match simple models of quantal transmission is rigorously compared with its ...
Stricker, Christian, Redman, Stephen
openaire   +5 more sources

Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging

Frontiers in Aging Neuroscience, 2021
The antidepressant drug amitriptyline is used in the treatment of clinical depression and a variety of neurological conditions such as anxiety, neuropathic pain disorders and migraine.
Eunyoung Bang, Angelika Tobery, Karienn S. Montgomery, Annette S. Fincher, David J. Earnest, David A. Murchison, William H. Griffith   +6 more
doaj   +1 more source

Unveiling the Synaptic Function and Structure Using Paired Recordings From Synaptically Coupled Neurons

Frontiers in Synaptic Neuroscience, 2020
Synaptic transmission between neurons is the basic mechanism for information processing in cortical microcircuits. To date, paired recording from synaptically coupled neurons is the most widely used method which allows a detailed functional ...
Guanxiao Qi, Danqing Yang, Chao Ding, Dirk Feldmeyer, Dirk Feldmeyer, Dirk Feldmeyer   +5 more
doaj   +1 more source

Estimation of cumulative amplitude distributions of miniature postsynaptic currents allows characterising their multimodality, quantal size and variability

Scientific Reports, 2023
A miniature postsynaptic current (mPSC) is a small, rare, and highly variable spontaneous synaptic event that is generally caused by the spontaneous release of single vesicles.
Susanna Gordleeva, Yulia Dembitskaya, Victor Kazantsev, Eugene B. Postnikov   +3 more
doaj   +1 more source

An explanation of anomalous behavior in models of political participation [PDF]

, 2005
This paper characterizes behavior with “noisy” decision making for models of political interaction characterized by simultaneous binary decisions. Applications include: voting participation games, candidate entry, the volunteer's dilemma, and collective ...
Goeree, Jacob K., Holt, Charles A.
core   +1 more source

One-particle exchange in the double folded potential in a semiclassical approximation [PDF]

, 1999
The one-particle exchange in the double folded model is analyzed. To this aim the Extended Thomas-Fermi approach to the one-body density matrix is used. The nucleon- nucleon force with Yukawa, Gauss and Coulomb-type form factors are considered.
Brack M, Campi X, Gridnev K A, Ismail M, Knyazkov O M, Krappe H J, Ring P, Soubbotin V B, Soubbotin V B, V B Soubbotin, X Viñas   +10 more
core   +2 more sources

Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex

Frontiers in Synaptic Neuroscience, 2019
Previous studies based on the ‘Quantal Model’ for synaptic transmission suggest that neurotransmitter release is mediated by a single release site at individual synaptic contacts in the neocortex.
Natalí Barros-Zulaica, John Rahmon, Giuseppe Chindemi, Rodrigo Perin, Henry Markram, Henry Markram, Eilif Muller, Srikanth Ramaswamy   +7 more
doaj   +1 more source

Extended Thomas-Fermi approximation to the one-body density matrix [PDF]

, 1999
The one-body density matrix is derived within the Extended Thomas-Fermi approximation. This has been done starting from the Wigner-Kirkwood distribution function for a non-local single-particle potential.
Anantaraman, Bertsch, Bonche, Bonche, Brack, Brack, Brack, Brack, Brack, Brack, Brink, Campi, Campi, Campi, Centelles, Centelles, Centelles, Decharge, Dreizler, Durand, Garcias, Grammaticos, Grammaticos, Guet, Guo-Qiang, Hofmann, Hohenberg, Ismail, Jennings, Jennings, Jennings, Khoa, Kohn, Krivine, Martorell, Meyer, Myers, Myers, Negele, Negele, Negele, Pi, Prakash, Shlomo, Soubbotin, Soubbotin, Soubottin, Sprung, Thierberger, V.B. Soubbotin, Vautherin, X. Viñas   +51 more
core   +2 more sources

Structural Properties of Synaptic Transmission and Temporal Dynamics at Excitatory Layer 5B Synapses in the Adult Rat Somatosensory Cortex

Frontiers in Synaptic Neuroscience, 2018
Cortical computations rely on functionally diverse and highly dynamic synapses. How their structural composition affects synaptic transmission and plasticity and whether they support functional diversity remains rather unclear.
Astrid Rollenhagen, Ora Ohana, Kurt Sätzler, Claus C. Hilgetag, Dietmar Kuhl, Joachim H. R. Lübke, Joachim H. R. Lübke, Joachim H. R. Lübke   +7 more
doaj   +1 more source

All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters [PDF]

, 2016
We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates.
Battiato, A., Bernardi, E., Carabelli, V., Carbone, E., Franchino, C., Gosso, S., Olivero, P., Pasquarelli, A., Picollo, F., Plaitano, M.   +9 more
core   +2 more sources