Results 231 to 240 of about 25,949 (265)
Some of the next articles are maybe not open access.

Quantit Analysis: A Quantal Assay Refinement

Biometrics, 1977
A new tolerance distribution and inference procedure for quantal response assays is presented. This method is capable of fitting a wide variety of shapes of response curves. Specific cases of this new method include quantal response assay analyses based on the double exponential distribution, the logistic distribution (logit analysis), and the uniform ...
Copenhaver, T. W., Mielke, P. W.
openaire   +2 more sources

Quantal analysis based on spectral methods

Pflügers Archiv European Journal of Physiology, 1994
A method for calculating quantal size based on spectral analysis of postsynaptic potential (PSP) amplitude distributions was developed and tested by Monte-Carlo techniques. It was combined with a test to reveal the bias of the estimate of quantal size and to determine whether the peaks in amplitude distributions reflect quantal release or a sampling ...
A E, Dityatev   +3 more
openaire   +2 more sources

Quantal analysis and long-term potentiation

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1998
Quantal analysis is useful for assessing the pre- and/or post-synaptic locus of the expression of long-term tetanic potentiation with the condition, however, that the studied synaptic potentials have been evoked by single cell stimulations, as is the case with paired recordings of identified neurons.
H, Korn, D S, Faber
openaire   +2 more sources

Limits of quantal analysis reliability: quantal and unimodal constraints and setting of confidence intervals for quantal size

Journal of Neuroscience Methods, 1993
An accurate objective method for determining the reliability of estimates of quantal size (Q) at central synapses was developed. To do this, distributions of amplitudes of postsynaptic responses were simulated by convolving a number of discrete amplitudes separated by equal increments Q with gaussian noise, after which the value of Q was estimated by ...
A E, Dityatev, H P, Clamann
openaire   +2 more sources

Doubts About Quantal Analysis

Journal of Neurophysiology, 2007
to the editor: In an impressive series of articles, Korn and co-workers (e.g., [Faber and Korn 1988][1]; [Faber et al. 1992][2], [1995][3]; [Korn et al. 1981][4], [1982][5], [1987][6]; reviews in [Korn and Faber 1991][7], [2005][8]) described electrophysiological recordings performed on ...
openaire   +1 more source

Direct Analysis of Quantal Radiation Response Data

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1986
A direct analysis is proposed for quantal (all-or-nothing) responses to fractionated radiation and endpoint-dilution assays of cell survival. As opposed to two-step methods such as the reciprocal-dose technique, in which ED50 values are first estimated for different fractionation schemes and then fit (as reciprocals) against dose per fraction, all raw ...
H D, Thames   +5 more
openaire   +2 more sources

Matrices in Quantal Analysis

Biometrics, 1955
Fisher (1954) has recently discussed the various transformations of probability used in the analysis of binomial data, and in that paper a full account of the statistical theory is given. While the assumption is often made that a distribution of thresholds must be postulated before efficient analysis may be made of binomial data (Finney, 1952a), Fisher
openaire   +1 more source

Presynaptic facilitation: Quantal analysis and simulations

Neurocomputing, 1999
Abstract The time-course of quantal neurosecretion indicated asynchrony in releases of presynaptic vesicles (quanta) in response to a stimulus. This was interpreted as reflecting the sequential release of vesicles from a single release site. We performed Monte-Carlo simulation of facilitated neurosecretion based upon the hypothesis that release sites
Maria Bykhovskaia   +2 more
openaire   +1 more source

Quantal and Graded Analysis of Dosage-Effect Relations

Science, 1961
Loewe's recommendations regarding treatment of stimulus-response relations are criticized. Conditions are described where quantal analysis is justified. Loewe's interpretation of his graded analysis must be modified in the light of the fact that response curves for individuals frequently cross. Superior lines of attack on the problem are suggested.
L J, CRONBACH, G C, GLESSER
openaire   +2 more sources

Analysis of Quantal Response Assays with Dosage Errors

Biometrics, 1967
This paper is conicerned with the problem of estimating the parameters of a tolerance distribution when the dose is subject to error of administration, and when observation is limited to the quantal, or all-or-lnone, respolise. The case when the errors in dose follow the Poisson law with known mean equal to the nominal dose is considered as a numerical
K M, Patwary, K D, Haley
openaire   +2 more sources

Home - About - Disclaimer - Privacy