Variability in the Munc13-1 content of excitatory release sites
eLife, 2021 The molecular mechanisms underlying the diversity of cortical glutamatergic synapses are still incompletely understood. Here, we tested the hypothesis that presynaptic active zones (AZs) are constructed from molecularly uniform, independent release sites
Maria Rita Karlocai +5 more
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Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction [PDF]
, 2017 Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells.
Bertone Cueto, Nicolás Iván +5 more
core +1 more source
Quantum fluctuation effects on hyperfragment formation from Xi^- absorption at rest on 12C
, 1998 Formation mechanisms of single, twin, and double hypernuclei from Xi^- absorption at rest on 12C are investigated with an refined microscopic transport model, that incorporates the recently developed Quantal Langevin treatment into Antisymmetrized ...
Akira Ohnishi +48 more
core +1 more source
Is friction responsible for the reduction of fusion rates far below the Coulomb barrier? [PDF]
, 2004 The fusion of two interacting heavy ions traditionally has been interpreted in terms of the penetration of the projectile into the target. Observed rates well below the Coulomb barrier are considerably lower than estimates obtained from penetration ...
Amos, K. +3 more
core +1 more source
Nature Communications, 2019 How neurotransmitter release relates to presynaptic calcium dynamics is not fully understood. Here the authors develop an approach based on FLIM and optical quantal analysis for simultaneous imaging of calcium dynamics and glutamate release at ...
Thomas P. Jensen +5 more
doaj +1 more source
Neuromuscular recovery from botulism involves multiple forms of compensatory plasticity
Frontiers in Cellular Neuroscience, 2023 IntroductionBotulinum neurotoxin (BoNT) causes neuroparalytic disease and death by blocking neuromuscular transmission. There are no specific therapies for clinical botulism and the only treatment option is supportive care until neuromuscular function ...
James B. Machamer +9 more
doaj +1 more source
Mode fluctuations as fingerprint of chaotic and non-chaotic systems
, 1996 The mode-fluctuation distribution $P(W)$ is studied for chaotic as well as for non-chaotic quantum billiards. This statistic is discussed in the broader framework of the $E(k,L)$ functions being the probability of finding $k$ energy levels in a randomly ...
Aurich, R., Bäcker, A., Steiner, F.
core +2 more sources
Medial Superior Olivary Neurons Receive Surprisingly Few Excitatory and Inhibitory Inputs with Balanced Strength and Short-Term Dynamics [PDF]
, 2010 Neurons in the medial superior olive (MSO) process microsecond interaural time differences, the major cue for localizing low-frequency sounds, by comparing the relative arrival time of binaural, glutamatergic excitatory inputs. This coincidence detection
Couchman, Kiri +2 more
core +2 more sources
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses
eLife, 2022 Ribbon synapses of cochlear inner hair cells (IHCs) are specialized to indefatigably transmit sound information at high rates. To understand the underlying mechanisms, structure-function analysis of the active zone (AZ) of these synapses is essential ...
Rituparna Chakrabarti +15 more
doaj +1 more source
Quantum Optical Aspects of High-Harmonic Generation
Photonics, 2021 The interaction of electrons with strong laser fields is usually treated with semiclassical theory, where the laser is represented by an external field. There are analytic solutions for the free electron wave functions, which incorporate the interaction ...
Sándor Varró
doaj +1 more source