Introduction: Tuberculosis (TB), caused by Mycobacterium tuberculosis, primarily affects the lungs but can involve virtually any organ system, manifesting as extrapulmonary TB. While TB‐related hypercoagulability and venous thromboembolism are recognized, such presentations remain uncommon and diagnostically challenging, especially in the absence of ...
Hamda Al-Mansoori +4 more
wiley +1 more source
Introduction: Tuberculosis infection (TBI) is diagnosed based on a positive immune response to M. tuberculosis antigens. This study aimed to evaluate both the qualitative and quantitative performance of two novel IGRA-based tests, the STANDARD E TB-Feron
Valeriu Crudu +6 more
doaj +1 more source
Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial [PDF]
Temprano ANRS 12136 was a factorial 2 × 2 trial that assessed the benefits of early antiretroviral therapy (ART; ie, in patients who had not reached the CD4 cell count threshold used to recommend starting ART, as per the WHO guidelines that were the ...
Badje, Anani +7 more
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Disseminated BCGosis After Intravesical BCG Installation for Bladder Cancer
We present three patients who developed BCGosis, a rare complication following intravesical Bacillus Calmette–Guérin (BCG) treatment for bladder cancer. These cases highlight the diverse clinical manifestations, diagnostic challenges, and management strategies of this entity, emphasizing the importance of early recognition and initiation of ...
Tyler Martinson +7 more
wiley +1 more source
A case of panuveitis with hypopyon due to presumed ocular leishmaniasis in a HIV patient. [PDF]
BACKGROUND: Post-kala-azar dermal leishmaniasis is a well-known immunologic cutaneous reaction. There are few case reports of ocular leishmaniasis. It is a sight-threatening condition that needs to be rapidly recognized and treated to avoid permanent ...
AM Hassan El +16 more
core +1 more source
In United States, Q fever cases increased from < 50 to 200 from 2000–2019. Case: 31‐year‐old female with fever after exposure to unpasteurized milk. Investigation revealed positive Q fever IgG. Trimethoprim–sulfamethoxazole and doxycycline were started due to QTc prolongation.
Pairie M. +5 more
wiley +1 more source
A Case of Evolving Hepatotoxicity Following Systemic Drug Reaction to Isoniazid–Rifapentine (3HP)
The 3‐month, once‐weekly regimen of isoniazid plus rifapentine (3HP) is widely used for latent tuberculosis infection (LTBI) because of its shorter duration and favorable adherence compared to isoniazid monotherapy. However, 3HP is associated with hepatotoxicity as well as systemic drug reactions (SDRs), characterized by rapid‐onset flu‐like symptoms ...
Niels Vizgan +4 more
wiley +1 more source
Maribel Gamon - Multidrug-Resistant Tuberculosis in India: Solving a Problem by Reconstructing the Public Health Infrastructure [PDF]
Mycobacterium tuberculosis, commonly referred to as TB, is responsible for causing about 630,000 cases per year of infectious diseases worldwide. Recently, multidrug resistant tuberculosis (MDR-TB) has become an alarming public health concern.
Gamon, Maribel
core +1 more source
Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania. [PDF]
Mycobacterium tuberculosis (Mtb) and helminth infections elicit antagonistic immune effector functions and are co-endemic in several regions of the world.
A Harari +115 more
core +4 more sources
What is the most effective treatment for acne rosacea? [PDF]
Topical metronidazole and azelaic acid are equally effective for the papulopustular lesions of acne rosacea, although metronidazole is better tolerated. Oral doxycycline, tetracycline, and metronidazole are also effective, but not enough evidence exists ...
Kelsberg, Gary +2 more
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