Factors Influencing False-Negative Results of QuantiFERON-TB Gold In-Tube (QFT-GIT) in Active Tuberculosis and the Desirability of Resetting Cutoffs for Different Populations: A Retrospective Study [PDF]
Tropical Medicine and Infectious Disease, 2022 Objectives The value of QuantiFERON-TB Gold In-Tube (QFT-GIT) in the diagnosis of TB varies by population, comorbidities, and other factors. In this study, we aimed to investigate factors that influence false-negative results of QFT-GIT test in the ...
Yuanyuan Yu, Qin Sun, Wei Sha
exaly +7 more sources
The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis [PDF]
BMC Immunology, 2022 Background Tuberculosis infection is a major complication of silicosis, but there is no study on whether silicosis can affect the sensitivity of QuantiFERON-TB Gold In-Tube (QFT-GIT) assays.
Jun-Chi Xu, Ye-Han Zhu, Zhu Ye-Han
exaly +5 more sources
Prospective Comparison of QFT-GIT and T-SPOT.TB Assays for Diagnosis of Active Tuberculosis [PDF]
Scientific Reports, 2018 AbstractT-SPOT.TB and QuantiFERON-TB Gold In-Tube (QFT-GIT) tests, as two commercial blood assays for diagnosing active tuberculosis (ATB), are not yet fully validated. Especially, there are no reports on comparing the efficacy between the two tests in the same population in China.
Fengjiao Du, Li Xie, Wei Sha
exaly +6 more sources
Comparison of QFT-Plus and QFT-GIT tests for diagnosis of M. tuberculosis infection in immunocompetent Korean subjects. [PDF]
J Thorac Dis, 2019 QFT-Plus is a recently developed next-generation QuantiFERON-TB Gold In-Tube (QFT-GIT) test. Unlike the QFT-GIT test, it includes a TB2 antigen tube with peptides that may stimulate CD8+ T cells. This study evaluated the diagnostic performance of QFT-Plus and compared it with that of QFT-GIT.QFT-Plus and QFT-GIT tests were performed in 33 patients with
Hong JY, Park SY, Kim A, Cho SN, Hur YG.
europepmc +7 more sources
Comparing the diagnostic performance of QuantiFERON-TB Gold Plus with QFT-GIT, T-SPOT.TB and TST: a systematic review and meta-analysis [PDF]
BMC Infectious Diseases, 2023 Abstract Background QuantiFERON-TB Gold Plus (QFT-Plus) is an important test that has emerged in recent years for detecting TB infection. We conducted a review to compare the sensitivity, specificity and positive rate of QFT-Plus with that of QuantiFERON-TB Gold In-Tube (QFT-GIT), T-cell spot ...
Zhang Y +8 more
exaly +5 more sources
Impact of correcting the lymphocyte count to improve the sensitivity of TB antigen-specific peripheral blood-based quantitative T cell assays (T-SPOT.®TB and QFT-GIT) [PDF]
Journal of Thoracic Disease, 2016 The standardized blood-based TB antigen-specific T cell assay, T-SPOT.(®)TB, is ~10% more sensitive than QuantiFERON(®)-TB-GIT (QFT-GIT) in detecting presumed latent TB infection (LTBI). Whilst T-SPOT.(®)TB uses a fixed number of lymphocytes per well, QFT-GIT uses a fixed volume of blood (~1 mL).
Richard N Van Zyl-Smit +2 more
exaly +5 more sources
Comparison of QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for diagnosis of latent tuberculosis in haemodialysis (HD) patients: a meta-analysis of κ estimates. [PDF]
Epidemiol Infect, 2017 SUMMARYDiagnosis of latent tuberculosis infection (LTBI) is a concern in haemodialysis (HD) patients. Many studies have compared QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for detecting LTBI and reported theκstatistic of agreement between QFT-GIT and TST in HD patients.
Ayubi E +7 more
europepmc +7 more sources
Microbiology Spectrum, 2022 QuantiFERON-TB Gold Plus (QFT-Plus) is an emerging QuantiFERON test after QuantiFERON-TB Gold In-Tube (QFT-GIT) for tuberculosis infection detection; it is an IFN-γ release assay.
Yuzhen Xu +2 more
exaly +3 more sources
Performance comparison of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus in detecting Mycobacterium tuberculosis infection among HIV patients in China [PDF]
PeerJIntroduction No direct comparative study assessing QuantiFERON-TB Gold In-Tube (QFT-GIT) and QuantiFERON-TB Gold Plus (QFT-Plus) for Mycobacterium tuberculosis infection among persons living with HIV (PLHIV) in China has been conducted.
Peng Lu +10 more
doaj +3 more sources
Evaluation of QuantiFERON TB gold plus among TB household contacts in high incidence settings [PDF]
BMC Infectious DiseasesBackground Accurately identifying and categorizing individuals who are latently infected is critical for developing prevention strategies against tuberculosis (TB) disease.
Sophie Nalukwago +7 more
doaj +2 more sources