Results 41 to 50 of about 21,986 (186)

Role of Quantiferon gold assay in the detection and follow-up of treatment of latent tuberculosis infection in some acquired immune-compromised patients

Egyptian Journal of Chest Disease and Tuberculosis, 2019
Background In patients latently infected with Mycobacterium tuberculosis, immunosuppression increases the risk of progression to active tuberculosis (TB), which is still considered one of the difficult and frequent opportunistic infections worldwide ...
Emad A Korra, Ibrahim A Dwedar, Eman B AbdelFattah, Azza H Hassan   +3 more
doaj   +1 more source

Cost-effectiveness of Quantiferon®-TB Gold-in-Tube versus tuberculin skin testing for contact screening and treatment of latent tuberculosis infection in Brazil. [PDF]

PLoS ONE, 2013
Latent tuberculosis infection (LTBI) is a reservoir for new TB cases. Isoniazid preventive therapy (IPT) reduces the risk of active TB by as much as 90%, but LTBI screening has limitations.
Ricardo Ewbank Steffen, Rosângela Caetano, Márcia Pinto, Diogo Chaves, Rossini Ferrari, Mayara Bastos, Sandra Teixeira de Abreu, Dick Menzies, Anete Trajman   +8 more
doaj   +1 more source

The diagnostic value of an interferon gamma release assay in new cases of active pulmonary tuberculosis and the factors influencing its negative results

Medicina Clínica Práctica, 2023
Objective: The aim of the study was to investigate the diagnostic value of an interferon gamma release assay (IGRA) - QuantiFERON-TB GOLD in-tube (QFT-GIT) - to identify new cases of active pulmonary tuberculosis (PTB) in Quzhou City, and to assess ...
Tao Lu, Ling Ye, Jianhua Lan, Shun Wang, Zhiyu Wu, Shugen Wu, Weili Lu, Chunxian Peng   +7 more
doaj   +1 more source

Diagnostic performance of culture filtered protein 10‐specific perforin in pediatric patients with active tuberculosis

Journal of Clinical Laboratory Analysis, Volume 34, Issue 11, November 2020., 2020
Diagnostic efficacy of CFP10‐specific perforin for TB diagnosis was higher than T‐SPOT assay. CFP10‐specific perforin effectively distinguishes between ATB and LTBI. CFP10‐specific perforin can be secreted by CD4+ and CD8+ T cells. Abstract Background Mycobacterium tuberculosis (Mtb)‐specific perforin were significantly increased in patients with ...
Qinzhen Cai, Xin Shen, Hongze Li, Cong Yao, Na Sun, Jun Wang, Huan Wu, Chunhui Yuan, Jie Xiang, Yun Xiang   +9 more
wiley   +1 more source

Risk factors associated with positive QuantiFERON-TB Gold In-Tube and tuberculin skin tests results in Zambia and South Africa.

PLoS ONE, 2011
IntroductionThe utility of T-cell based interferon-gamma release assays for the diagnosis of latent tuberculosis infection remains unclear in settings with a high burden of tuberculosis.ObjectivesTo determine risk factors associated with positive ...
Kwame Shanaube, James Hargreaves, Katherine Fielding, Ab Schaap, Katherine-Anne Lawrence, Bernadette Hensen, Charalambos Sismanidis, Angela Menezes, Nulda Beyers, Helen Ayles, Peter Godfrey-Faussett   +10 more
doaj   +1 more source

How are high burden countries implementing policies and tools for latent tuberculosis infection? A survey of current practices and barriers

Health Science Reports, Volume 3, Issue 2, June 2020., 2020
Abstract Background and aims Despite the World Health Organization (WHO)'s updated guidelines on tuberculosis (TB) preventive treatment, the scale‐up of TB preventive therapy remains low in many high‐burden countries (HBCs). We conducted a survey to better understand the current status of policy implementation and barriers for scale‐up.
Lena Faust, Morten Ruhwald, Samuel Schumacher, Madhukar Pai   +3 more
wiley   +1 more source

Predictors for false-negative QuantiFERON-TB Gold assay results in patients with extrapulmonary tuberculosis

BMC Infectious Diseases, 2018
Backgrounds Extrapulmonary tuberculosis (EPTB) is a heterogeneous disease, and diagnosis is sometimes difficult. We investigated the diagnostic performance of the QuantiFERON-TB Gold assay (QFT-GIT) according to sites of EPTB and predictors for false ...
Youn Jeong Kim, Ji Young Kang, Sang Il Kim, Mee Soo Chang, Yang Ree Kim, Yeon Joon Park   +5 more
doaj   +1 more source

Utility of QuantiFERON tuberculosis gold-in-tube test for detecting latent tuberculosis infection among close household contacts of confirmed tuberculosis patients in Accra, Ghana

International Journal of Mycobacteriology, 2017
Objective/Background: Introduction of the interferon gamma (IFN-γ) release assays with their higher sensitivity and specificity over the traditional tuberculin skin test has improved testing for latent tuberculosis infection (LTBI).
Gloria Ivy Mensah, Sandra Akoley Sowah, Nana Yaw Asare Yeboah, Kennedy Kwasi Addo, Dolly Jackson-Sillah   +4 more
doaj   +1 more source

UEG Week 2023 Poster Presentations

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 535-1498, October 2023.
wiley   +1 more source

Flow of LTBI patient evaluation and testing at BCHD in the post-QFT-GIT period.

, 2012
*Among 750 referrals, 690 had a TST by referring source, 23 had a QFT-GIT by the referring source, and 5 had both a QFT-GIT and TST performed by referral source); 32 individuals were referred as B-Waivers without prior LTBI testing based on abnormal CXR ...
Susan E. Dorman (143301), Maunank Shah (143318), Sherry Ketemepi (166132), Adena Greenbaum (166127), Maria Martins-Evora (166138), Vincent Marsiglia (166145), Danielle DiPietro (166121)   +6 more
core   +1 more source