Comparison between the Interferon γ Release Assay—QuantiFERON Gold Plus (QFT-Plus)—and Tuberculin Skin Test (TST) in the Detection of Tuberculosis Infection in Immunocompromised Children [PDF]
Background. Immunocompromised patients are at a higher risk of having latent tuberculosis infection (LTBI). QuantiFERON-TB Gold Plus (QFT-Plus) has been proven to perform effectively in LTBI detection among immunocompromised adults and can overcome the ...
Cory Primaturia +2 more
doaj +3 more sources
QFT-Plus: a plus in variability? – Evaluation of new generation IGRA in serial testing of students with a migration background in Germany [PDF]
BackgroundCurrently available Interferon-gamma release assays (IGRAs) show a considerable variability in serial testing for latent tuberculosis infection (LTBI).This study offers first results for the new generation IGRA QuantiFERON-TB Gold Plus (QFT ...
Nienhaus A, A Nienhaus
exaly +3 more sources
Background QuantiFERON-TB Gold Plus (QFT-Plus) is an important test that has emerged in recent years for detecting TB infection. We conducted a review to compare the sensitivity, specificity and positive rate of QFT-Plus with that of QuantiFERON-TB Gold ...
Yu Zhang +8 more
exaly +3 more sources
Performance evaluation of the AFIAS IGRA-TB (IFN-gamma) test versus QuantiFERON®-TB gold plus (QFT®-Plus) ELISA in the Barrio Obrero hospital network, Asunción—Paraguay, 2025 [PDF]
BackgroundTuberculosis infection affects an estimated one-quarter of the global population and represents a key target for TB elimination strategies.
Cynthia Céspedes +12 more
doaj +3 more sources
QuantiFERON-TB Gold Plus CD8+ T cell responses in contacts with tuberculosis disease and recent tuberculosis infection [PDF]
The QuantiFERON-TB Gold Plus (QFT-Plus) replaced the QuantiFERON-TB Gold in-tube (QFT-GIT) in 2016 to increase assay sensitivity, based on the role of Mycobacterium tuberculosis-specific CD8+ T cells in the host response to tuberculosis infection (TBI ...
Cynthia Bin-Eng Chee +3 more
doaj +3 more sources
Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024 [PDF]
Objectives Tuberculosis screening in pediatric lupus nephritis (LN) patients presents unique diagnostic challenges. This study aimed to analyze the frequency of indeterminate QuantiFERON-TB Gold Plus (QFT-Plus) results among children with LN and the ...
Yue Xi +10 more
doaj +3 more sources
Comparison of QFT-Plus and QFT-GIT tests for diagnosis of M. tuberculosis infection in immunocompetent Korean subjects. [PDF]
Background QFT-Plus is a recently developed next-generation QuantiFERON-TB Gold In-Tube (QFT-GIT) test. Unlike the QFT-GIT test, it includes a TB2 antigen tube with peptides that may stimulate CD8+ T cells. This study evaluated the diagnostic performance
Hong JY, Park SY, Kim A, Cho SN, Hur YG.
europepmc +2 more sources
Characterization of QuantiFERON-TB-Plus Results in Patients with Tuberculosis Infection and Multiple Sclerosis [PDF]
Background: Disease-modifying drugs (DMDs) for multiple sclerosis (MS) slightly increase the risk of tuberculosis (TB) disease. The QuantiFERON-TB-Plus (QFT-Plus) test is approved for TB infection (TBI) screening.
Elisa Petruccioli +14 more
doaj +3 more sources
Factors associated with indeterminate QuantiFERON-TB Gold Plus Test results during the COVID-19 pandemic. [PDF]
ObjectiveIndeterminate QuantiFERON (QFT) results challenge clinical decision-making and often necessitate repeat testing. This study aimed to assess the prevalence of indeterminate QFT results and identify associated factors.MethodWe compared patients ...
Carla M Román-Montes +11 more
doaj +3 more sources
TB antigen-based skin tests and QFT-Plus for Mycobacterium tuberculosis infection diagnosis in Brazilian healthcare workers: a cost-effectiveness analysis. [PDF]
This study aimed to analyze the cost-effectiveness of three tuberculosis (TB) antigen-based skin tests (TBST) (Diaskintest, C-TST, and Cy-TB) and QFT-Plus for TB infection diagnosis compared to the current standard of care, PPD Rt-23 tuberculin skin test
Souza FM +5 more
europepmc +2 more sources

