Comparison between the Interferon γ Release Assay—QuantiFERON Gold Plus (QFT-Plus)—and Tuberculin Skin Test (TST) in the Detection of Tuberculosis Infection in Immunocompromised Children [PDF]
Background. Immunocompromised patients are at a higher risk of having latent tuberculosis infection (LTBI). QuantiFERON-TB Gold Plus (QFT-Plus) has been proven to perform effectively in LTBI detection among immunocompromised adults and can overcome the ...
Cory Primaturia +2 more
doaj +4 more sources
QFT-Plus: a plus in variability? – Evaluation of new generation IGRA in serial testing of students with a migration background in Germany [PDF]
Currently available Interferon-gamma release assays (IGRAs) show a considerable variability in serial testing for latent tuberculosis infection (LTBI). This study offers first results for the new generation IGRA QuantiFERON-TB Gold Plus (QFT-Plus) introduced in 2015 in comparison with its predecessor QuantiFERON-TB Gold In-Tube (QFT-GIT) from serial ...
A Schablon, A Nienhaus
exaly +5 more sources
Comparison of QFT-Plus and QFT-GIT tests for diagnosis of M. tuberculosis infection in immunocompetent Korean subjects. [PDF]
QFT-Plus is a recently developed next-generation QuantiFERON-TB Gold In-Tube (QFT-GIT) test. Unlike the QFT-GIT test, it includes a TB2 antigen tube with peptides that may stimulate CD8+ T cells. This study evaluated the diagnostic performance of QFT-Plus and compared it with that of QFT-GIT.QFT-Plus and QFT-GIT tests were performed in 33 patients with
Hong JY, Park SY, Kim A, Cho SN, Hur YG.
europepmc +5 more sources
QuantiFERON-TB Gold Plus (QFT-Plus) is an emerging QuantiFERON test after QuantiFERON-TB Gold In-Tube (QFT-GIT) for tuberculosis infection detection; it is an IFN-γ release assay.
Yuzhen Xu +9 more
doaj +3 more sources
TB antigen-based skin tests and QFT-Plus for Mycobacterium tuberculosis infection diagnosis in Brazilian healthcare workers: a cost-effectiveness analysis. [PDF]
This study aimed to analyze the cost-effectiveness of three tuberculosis (TB) antigen-based skin tests (TBST) (Diaskintest, C-TST, and Cy-TB) and QFT-Plus for TB infection diagnosis compared to the current standard of care, PPD Rt-23 tuberculin skin test (TST), among healthcare workers in Brazil. A state-transition Markov model was employed, simulating
Souza FM +5 more
europepmc +5 more sources
Background QuantiFERON-TB Gold Plus (QFT-Plus) is an important test that has emerged in recent years for detecting TB infection. We conducted a review to compare the sensitivity, specificity and positive rate of QFT-Plus with that of QuantiFERON-TB Gold ...
Yu Zhang +8 more
doaj +2 more sources
Successful transition to the QFT-PLUS assay, but more is needed for diagnosis of latent tuberculosis infection. [PDF]
Lee EH, Kang YA.
europepmc +5 more sources
Comparison of QFT-IT and QFT-Plus for Detecting Latent Tuberculosis in HIV-Infected Iranian Patients
Background: Tuberculosis (TB) is a major public health issue, especially among Human immunodeficiency virus (HIV)-infected individuals, where early detection of latent tuberculosis infection (LTBI) is crucial.
Zahra Abtahian +4 more
doaj +2 more sources
A cost-effectiveness evaluation of methods for screening for TB infection in patients with diabetes mellitus [PDF]
BACKGROUND: Globally, 10.6 million TB cases occurred in 2021. Malaysia reported 25,000 TB cases in 2022, and also has a high prevalence of diabetes mellitus (DM), amplifying TB risks.
M.I. Mahmood +4 more
doaj +2 more sources
Immune Sensitization to Mycobacterium tuberculosis Among Young Children with and without Tuberculosis [PDF]
Identification of young children with Mycobacterium tuberculosis (Mtb) infection is critical to curb pediatric morbidity and mortality. The optimal test to identify young children with Mtb infection remains controversial.
Jesús Gutierrez +12 more
doaj +2 more sources

