Results 11 to 20 of about 1,907 (170)

A cost-effectiveness evaluation of methods for screening for TB infection in patients with diabetes mellitus [PDF]

IJTLD Open
BACKGROUND: Globally, 10.6 million TB cases occurred in 2021. Malaysia reported 25,000 TB cases in 2022, and also has a high prevalence of diabetes mellitus (DM), amplifying TB risks.
M.I. Mahmood, M. Ganason, Z.A. Aziz, S.H. Ramli, S.H.A. Halim   +4 more
doaj   +2 more sources

Immune Sensitization to Mycobacterium tuberculosis Among Young Children with and without Tuberculosis [PDF]

Pathogens
Identification of young children with Mycobacterium tuberculosis (Mtb) infection is critical to curb pediatric morbidity and mortality. The optimal test to identify young children with Mtb infection remains controversial.
Jesús Gutierrez, LaShaunda L. Malone, Mitchka Mohammadi, John Mukisa, Michael Atuhairwe, Simon Peter G. Mwesigwa, Salome Athieno, Sharon Buwule, Faith Ameda, Sophie Nalukwago, Ezekiel Mupere, Catherine M. Stein, Christina L. Lancioni   +12 more
doaj   +2 more sources

Performance evaluation of the AFIAS IGRA-TB (IFN-gamma) test versus QuantiFERON®-TB gold plus (QFT®-Plus) ELISA in the Barrio Obrero hospital network, Asunción—Paraguay, 2025 [PDF]

Frontiers in Public Health
BackgroundTuberculosis infection affects an estimated one-quarter of the global population and represents a key target for TB elimination strategies.
Cynthia Céspedes, Cynthia Céspedes, Jessica Riveros, Jessica Riveros, Antonio Villalba, Sandra Gutierrez, Roxana Ocampo, Adán Godoy, Sarita Aguirre, Angélica Medina, Angélica Medina, Guillermo Sequera, Guillermo Sequera   +12 more
doaj   +2 more sources

First evaluation of QuantiFERON-TB Gold Plus performance in contact screening [PDF]

European Respiratory Journal, 2016
Identifying latently infected individuals is crucial for the elimination of tuberculosis (TB). We evaluated for the first time the performance of a new type of interferon-γ release assay, QuantiFERON-TB Plus (QFT-Plus), which includes an additional ...
Emanuele Borroni, James Brown, Enrico Brunetti   +2 more
exaly   +3 more sources

Performance comparison of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus in detecting Mycobacterium tuberculosis infection among HIV patients in China [PDF]

PeerJ
Introduction No direct comparative study assessing QuantiFERON-TB Gold In-Tube (QFT-GIT) and QuantiFERON-TB Gold Plus (QFT-Plus) for Mycobacterium tuberculosis infection among persons living with HIV (PLHIV) in China has been conducted.
Peng Lu, Haitao Yang, Fang Ge, Kai Wu, Yilin Lian, Xiaoyan Ding, Jingjing Pan, Hui Ding, Wei Lu, Qiao Liu, Limei Zhu   +10 more
doaj   +3 more sources

QuantiFERON-TB Gold Plus CD8+ T cell responses in contacts with tuberculosis disease and recent tuberculosis infection [PDF]

Microbiology Spectrum
The QuantiFERON-TB Gold Plus (QFT-Plus) replaced the QuantiFERON-TB Gold in-tube (QFT-GIT) in 2016 to increase assay sensitivity, based on the role of Mycobacterium tuberculosis-specific CD8+ T cells in the host response to tuberculosis infection (TBI ...
Cynthia Bin-Eng Chee, KhinMar Kyi-Win, Shera Tan, Yee-Tang Wang   +3 more
doaj   +2 more sources

Evaluation of QIAreach QuantiFERON-TB lateral-flow nanoparticle fluorescence assay for TB infection diagnosis among TB household contacts in three high-burden settings. [PDF]

PLoS ONE
BackgroundTuberculosis infection (TBI) testing, and treatment are fundamental to achieve TB elimination. TBI testing among close or household contacts (HHCs) has been limited, in part due to perceived complexity and high operational cost.
Thobani Ntshiqa, Akinlolu Fasanmi, Jeniffer Nagudi, Lindiwe Tsope, Andrew Copas, Stacie Stender, Issa Sabi, Elias Nyanda Ntinginya, Julieth Lalashowi, Manthomeng Matete, Lula Budiaki, Malebo Mahlalela, Abisai Kisinda, Don Mudzengi, Lilian Tina Minja, Tobias Chirwa, Knut Lönnroth, Stefan Niemann, Viola Dreyer, Salome Charalambous, Kavindhran Velen, Yohhei Hamada, Molebogeng Rangaka   +22 more
doaj   +2 more sources

Evaluation of QuantiFERON TB gold plus among TB household contacts in high incidence settings [PDF]

BMC Infectious Diseases
Background Accurately identifying and categorizing individuals who are latently infected is critical for developing prevention strategies against tuberculosis (TB) disease.
Sophie Nalukwago, Bonnie Thiel, Keith Chervenak, AnnaRitah Namuganga, LaShaunda L. Malone, Mary Nsereko, W. Henry Boom, Harriet Mayanja-Kizza   +7 more
doaj   +2 more sources

Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024 [PDF]

BMC Nephrology
Objectives Tuberculosis screening in pediatric lupus nephritis (LN) patients presents unique diagnostic challenges. This study aimed to analyze the frequency of indeterminate QuantiFERON-TB Gold Plus (QFT-Plus) results among children with LN and the ...
Yue Xi, Huiwen Zheng, Yonghong Wang, Yajie Guo, Jing Xiao, Feina Li, Hui Qi, Weiwei Jiao, Nan Zhou, Zhi Chen, Lin Sun   +10 more
doaj   +2 more sources

Optimizing tuberculosis infection screening strategies for people living with HIV in Thailand: a cost-effectiveness analysis [PDF]

BMC Public Health
Background To support evidence-based decision-making in Thailand, we assessed the cost-effectiveness of QuantiFERON-TB Gold Plus (QFT-Plus) compared to the Tuberculin Skin Test (TST) in people living with HIV (PLWH).
Nuntana Chumpa, Pirapon June Ohata, Gompol Suwanpimolkul   +2 more
doaj   +2 more sources