Results 11 to 20 of about 1,484 (134)

Performance evaluation of the AFIAS IGRA-TB (IFN-gamma) test versus QuantiFERON®-TB gold plus (QFT®-Plus) ELISA in the Barrio Obrero hospital network, Asunción—Paraguay, 2025 [PDF]

Frontiers in Public Health
BackgroundTuberculosis infection affects an estimated one-quarter of the global population and represents a key target for TB elimination strategies.
Cynthia Céspedes, Cynthia Céspedes, Jessica Riveros, Jessica Riveros, Antonio Villalba, Sandra Gutierrez, Roxana Ocampo, Adán Godoy, Sarita Aguirre, Angélica Medina, Angélica Medina, Guillermo Sequera, Guillermo Sequera   +12 more
doaj   +2 more sources

QuantiFERON-TB Gold Plus CD8+ T cell responses in contacts with tuberculosis disease and recent tuberculosis infection [PDF]

Microbiology Spectrum
The QuantiFERON-TB Gold Plus (QFT-Plus) replaced the QuantiFERON-TB Gold in-tube (QFT-GIT) in 2016 to increase assay sensitivity, based on the role of Mycobacterium tuberculosis-specific CD8+ T cells in the host response to tuberculosis infection (TBI ...
Cynthia Bin-Eng Chee, KhinMar Kyi-Win, Shera Tan, Yee-Tang Wang   +3 more
doaj   +2 more sources

Evaluation of QIAreach QuantiFERON-TB lateral-flow nanoparticle fluorescence assay for TB infection diagnosis among TB household contacts in three high-burden settings. [PDF]

PLoS ONE
BackgroundTuberculosis infection (TBI) testing, and treatment are fundamental to achieve TB elimination. TBI testing among close or household contacts (HHCs) has been limited, in part due to perceived complexity and high operational cost.
Thobani Ntshiqa, Akinlolu Fasanmi, Jeniffer Nagudi, Lindiwe Tsope, Andrew Copas, Stacie Stender, Issa Sabi, Elias Nyanda Ntinginya, Julieth Lalashowi, Manthomeng Matete, Lula Budiaki, Malebo Mahlalela, Abisai Kisinda, Don Mudzengi, Lilian Tina Minja, Tobias Chirwa, Knut Lönnroth, Stefan Niemann, Viola Dreyer, Salome Charalambous, Kavindhran Velen, Yohhei Hamada, Molebogeng Rangaka   +22 more
doaj   +2 more sources

Optimizing tuberculosis infection screening strategies for people living with HIV in Thailand: a cost-effectiveness analysis [PDF]

BMC Public Health
Background To support evidence-based decision-making in Thailand, we assessed the cost-effectiveness of QuantiFERON-TB Gold Plus (QFT-Plus) compared to the Tuberculin Skin Test (TST) in people living with HIV (PLWH).
Nuntana Chumpa, Pirapon June Ohata, Gompol Suwanpimolkul   +2 more
doaj   +2 more sources

Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024 [PDF]

BMC Nephrology
Objectives Tuberculosis screening in pediatric lupus nephritis (LN) patients presents unique diagnostic challenges. This study aimed to analyze the frequency of indeterminate QuantiFERON-TB Gold Plus (QFT-Plus) results among children with LN and the ...
Yue Xi, Huiwen Zheng, Yonghong Wang, Yajie Guo, Jing Xiao, Feina Li, Hui Qi, Weiwei Jiao, Nan Zhou, Zhi Chen, Lin Sun   +10 more
doaj   +2 more sources

Characterization of QuantiFERON-TB-Plus Results in Patients with Tuberculosis Infection and Multiple Sclerosis [PDF]

Neurology International
Background: Disease-modifying drugs (DMDs) for multiple sclerosis (MS) slightly increase the risk of tuberculosis (TB) disease. The QuantiFERON-TB-Plus (QFT-Plus) test is approved for TB infection (TBI) screening.
Elisa Petruccioli, Luca Prosperini, Serena Ruggieri, Valentina Vanini, Andrea Salmi, Gilda Cuzzi, Simonetta Galgani, Shalom Haggiag, Carla Tortorella, Gabriella Parisi, Alfio D’Agostino, Gina Gualano, Fabrizio Palmieri, Claudio Gasperini, Delia Goletti   +14 more
doaj   +2 more sources

Concordance of TST and QFT-Plus, Sensitivity and Specificity of TST and QFT-Plus in Detection of LTBI in MDR TB Contact [PDF]

Jurnal Respirologi Indonesia, 2022
Background: Tuberculosis (TB) is an infectious disease and the main cause of world health problems. Not all individuals infected with Mycobacterium tuberculosis (Mtb) develop active TB. Latent tuberculosis infection (LTBI) is a state of persistent immune response to stimulation of the Mtb antigen with no evidence of clinically manifest active TB ...
Rullyano Hardian, Reviono Reviono, Harsini Kusumo, Yusup Subagio Sutanto   +3 more
openaire   +1 more source

Factors associated with indeterminate QuantiFERON-TB Gold Plus Test results during the COVID-19 pandemic. [PDF]

PLoS ONE
ObjectiveIndeterminate QuantiFERON (QFT) results challenge clinical decision-making and often necessitate repeat testing. This study aimed to assess the prevalence of indeterminate QFT results and identify associated factors.MethodWe compared patients ...
Carla M Román-Montes, Karla M Tamez-Torres, Guillermo A Guaracha-Basañez, Alberto Ordinola-Navarro, Marco Antonio Ortiz-Bustamante, Sandra Rajme-López, Bernardo A Martínez-Guerra, Anabel Ordaz-Vázquez, José Sifuentes-Osornio, Alfredo Ponce-de-León, Fernanda González-Lara, Miriam Bobadilla-Del-Valle   +11 more
doaj   +2 more sources

Cost-effectiveness of IGRA/QFT-Plus for TB screening of migrants in Oman [PDF]

International Journal of Infectious Diseases, 2020
To estimate the cost of a screening program for identifying latent tuberculosis (TB) infections in migrants to Oman.A Markov model was used to estimate the cost of screening using an interferon-gamma release assay (IGRA) applied to all migrants from high TB endemic countries, followed by preventive TB treatment.The model compared seven different ...
Al Abri, Seif, Kowada, Akiko, Yaqoubi, Fatma, Al Khalili, Sulien, Ndunda, Nduku, Petersen, Eskild   +5 more
openaire   +3 more sources

Comparing QuantiFERON-TB Gold Plus with QuantiFERON-TB Gold in-tube for diagnosis of latent tuberculosis infection among highly TB exposed gold miners in South Africa [version 3; peer review: 2 approved, 1 approved with reservations]

Gates Open Research, 2022
Background: QuantiFERON-TB-Gold-in-tube (QFT-GIT) is an interferon-gamma release assay (IGRA) used to diagnose latent tuberculosis infection. Limited data exists on performance of QuantiFERON-TB Gold-Plus (QFT-Plus), a next generation of IGRA that ...
Alison D. Grant, Thobani Ntshiqa, Raoul Mansukhani, Violet Chihota, Kavindhran Velen, Salome Charalambous, Lindiwe Nhlangulela, Thomas R. Hawn, Pholo Maenetje, Gavin Churchyard, Katherine Fielding, Robert Wallis   +11 more
doaj   +1 more source