Comparison of LIAISON QuantiFERON-TB Gold Plus with QuantiFERON-TB Gold Plus [PDF]
Microbiology Spectrum, 2023 AbstractWith the large global burden of latent tuberculosis (TB) infection (LTBI), screening for LTBI for various reasons has become standard practice including the low-prevalence settings.The results showed acceptable intra- and inter-run precision as well as cutoff verification across the two analyzers at the afore-mentioned levels (Table 1). Overall,
Kamran Kadkhoda +2 more
doaj +4 more sources
Identification of Recent Tuberculosis Exposure Using QuantiFERON-TB Gold Plus, a Multicenter Study [PDF]
Microbiology Spectrum, 2021 We investigated whether the difference of antigen tube 2 (TB2) minus antigen tube 1 (TB1) (TB2−TB1) of the QuantiFERON-TB gold plus test, which has been postulated as a surrogate for the CD8+ T-cell response, could be useful in identifying recent ...
Sandra Pérez-Recio +36 more
doaj +13 more sources
Predicting stringent QuantiFERON-TB Gold Plus conversions in contacts of tuberculosis patients [PDF]
Journal of Microbiology, Immunology and Infection, 2023 Objectives: To assess associations between disease severity in index TB patients and QuantiFERON-TB Gold Plus (QFT-Plus) results in contacts, and predictors for QFT-Plus conversion in contacts over 6–12 months.
Sheng-Wei Pan +11 more
doaj +6 more sources
A regression predictive model for QuantiFERON-TB Gold Plus indeterminate results in immunosuppressed patients [PDF]
SAGE Open MedicineBackground: Screening for latent tuberculosis infection using Interferon-Gamma Release Assays is a routine procedure prior to the initiation of anti-tumor necrosis factor (TNF) biotherapy or immunosuppressive therapy.
Rahma Bellagha +9 more
doaj +4 more sources
LIOFeron®TB/LTBI: A novel and reliable test for LTBI and tuberculosis [PDF]
International Journal of Infectious Diseases, 2020 Objectives: High accuracy diagnostic screening tests for tuberculosis (TB) are required to improve the diagnosis of both active TB and latent Mycobacterium tuberculosis (MTB) infection (LTBI).
Chiara Della Bella +16 more
doaj +4 more sources
QuantiFERON-TB Gold Plus CD8+ T cell responses in contacts with tuberculosis disease and recent tuberculosis infection [PDF]
Microbiology SpectrumThe QuantiFERON-TB Gold Plus (QFT-Plus) replaced the QuantiFERON-TB Gold in-tube (QFT-GIT) in 2016 to increase assay sensitivity, based on the role of Mycobacterium tuberculosis-specific CD8+ T cells in the host response to tuberculosis infection (TBI ...
Cynthia Bin-Eng Chee +3 more
doaj +2 more sources
Comparing the diagnostic performance of QuantiFERON-TB Gold Plus with QFT-GIT, T-SPOT.TB and TST: a systematic review and meta-analysis [PDF]
BMC Infectious Diseases, 2023 Background QuantiFERON-TB Gold Plus (QFT-Plus) is an important test that has emerged in recent years for detecting TB infection. We conducted a review to compare the sensitivity, specificity and positive rate of QFT-Plus with that of QuantiFERON-TB Gold ...
Yu Zhang +8 more
doaj +2 more sources
Comparison of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold-Plus in the Diagnosis of Mycobacterium tuberculosis Infections in Immunocompromised Patients: a Real-World Study [PDF]
Microbiology Spectrum, 2022 QuantiFERON-TB Gold Plus (QFT-Plus) is an emerging QuantiFERON test after QuantiFERON-TB Gold In-Tube (QFT-GIT) for tuberculosis infection detection; it is an IFN-γ release assay.
Yuzhen Xu +9 more
doaj +2 more sources
Evaluation of the performance of QuantiFERON®-TB Gold plus test in active tuberculosis patients
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021 The aim was to evaluate the sensitivity and the possible factors affecting the sensitivity of the QuantiFERON®-TB Gold Plus (QFT-Plus) assay in culture-positive active TB (Tuberculosis) patients, to investigate the possible causes of negative and ...
Cengiz Çavuşoğlu +4 more
doaj +3 more sources
A detailed analysis of borderline results in the QuantiFERON-TB Gold-Plus assay incorporating longitudinal follow-up: intermediate-burden setting [PDF]
Microbiology SpectrumThe QuantiFERON-TB Gold Plus (QFT-Plus; Qiagen, Hilden, Germany) assay is widely used for latent TB infection (LTBI) screening; however, borderline results often show variability during follow-up.
Eunju Shin +6 more
doaj +2 more sources