Results 31 to 40 of about 2,328 (144)

Equal sensitivity of the new generation QuantiFERON-TB Gold plus in direct comparison with the presious test version QuantiFERON-TB Gold IT [PDF]

open access: yesPneumologie, 2016
QuantiFERON-TB Gold IT analyses interferon-γ release from CD4(+) T cells after stimulation with specific tuberculosis (TB) antigens. Its sensitivity is approximately 80% for active TB. A new test generation (QFTGplus) also analyses the response of CD8(+) T cells.
H, Hoffmann   +4 more
openaire   +2 more sources

Comparative Evaluation of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus in Diagnosis of Latent Tuberculosis Infection in Immunocompromised Patients [PDF]

open access: yesJournal of Clinical Microbiology, 2018
QuantiFERON-TB Gold Plus (QFT-Plus) is a new-generation QuantiFERON-TB Gold In-Tube (QFT-GIT) assay which has two antigen-coated tubes called TB1, which contains long peptides derived from ESAT-6 and CFP-10, and TB2, which contains the same components as TB1 and additional short peptides which potentially stimulate CD8 +
Mi Ra, Ryu   +18 more
openaire   +2 more sources

Comparative Results of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus Assays for Detection of Tuberculosis Infection in Clinical Samples

open access: yesJournal of Clinical Microbiology, 2020
The QuantiFERON-TB Gold plus (QFT-Plus) assay, an interferon gamma (IFN-γ) release assay (IGRA), was recently introduced as the next version of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay for diagnosing latent tuberculosis (TB). Whereas the QFT-GIT assay uses only one TB tube that induces a cell-mediated immune (CMI) response of CD4
Dongju Won   +3 more
openaire   +4 more sources

Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners

open access: yesPLoS ONE, 2022
Background Despite high exposure to Mycobacterium tuberculosis, a small proportion of South African goldminers resist TB infection. We determined, among long-service gold miners i) the proportion who were TB uninfected and ii) epidemiological factors ...
Violet N. Chihota   +9 more
doaj   +3 more sources

A cost-effectiveness evaluation of latent tuberculosis infection screening of a migrant population in Malaysia

open access: yesScientific Reports, 2023
To estimate the costs and benefits of screening for latent tuberculosis infection (LTBI) in a migrant population in Malaysia. An economic model was developed from a Malaysian healthcare perspective to compare QuantiFERON-TB Gold Plus (QuantiFERON) with ...
Erin Barker   +8 more
doaj   +1 more source

Comparison of Sensitivity between Mantoux test, Quantiferon-TB Gold with Bronchoalveolar Lavage for GeneXpert in Renal Transplant for Latent Tuberculosis

open access: yesPakistan Armed Forces Medical Journal
Objectives: To compare the sensitivity of the Mantoux test and QuantiFERON-TB Gold plus assay for diagnosing latent tuberculosis in patients of chronic kidney disease being considered for living renal transplant. Study Design: Cross-sectional study.
Ghulam Mustafa   +5 more
doaj   +1 more source

First evaluation of the performance of portable IGRA, QIAreach® QuantiFERON®-TB in intermediate TB incidence setting.

open access: yesPLoS ONE, 2023
Diagnosis and treatment of tuberculosis infection (TBI) are the core elements of tuberculosis elimination. Interferon gamma release assays have advantages over the tuberculin skin test, although their implementation in low-resource settings is ...
Zirwatul Adilah Aziz   +3 more
doaj   +1 more source

Implementing contact tracing for tuberculosis in Kyrgyz Republic and risk factors for positivity using QuantiFERON-TB Gold plus

open access: yesBMC Infectious Diseases, 2020
Background Effective active case finding (ACF) activities are essential for early identification of new cases of active tuberculosis (TB) and latent TB infection (LTBI).
Caroline Corbett   +14 more
doaj   +1 more source

Utility of blood‐based Mycobacterium tuberculosis antigen‐specific host biomarkers in differentiating between spinal tuberculosis and mechanical back pain: A proof‐of‐concept study

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Spinal tuberculosis (TB) is a severe form of musculoskeletal TB whose diagnosis remains challenging and may be misinterpreted as mechanical back pain. Mycobacterium tuberculosis antigen‐specific host blood protein biomarkers detectable in QuantiFERON supernatants may offer greater specificity to distinguish spinal TB from mechanical back pain, with ...
Bih H. Chendi   +5 more
wiley   +1 more source

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