Results 51 to 60 of about 2,328 (144)

Research priorities for advanced HIV disease in Latin America and the Caribbean region: a modified Delphi study

Journal of the International AIDS Society, Volume 29, Issue 1, January 2026.
Abstract Introduction Advanced HIV disease (AHD) remains a leading cause of mortality in Latin America and the Caribbean (LAC), driven by late diagnosis, treatment gaps and structural barriers, particularly among key populations and children. Persistent disparities in healthcare access, stigma, and limited health system capacity highlight the need for ...
Evelina Chapman, Omar Sued, Jorge O. Maia Barreto, Claudia P. Cortes, Brenda Crabtree Ramírez, José E. Vidal, Antonio Camiro‐Zúñiga, Freddy Perez   +7 more
wiley   +1 more source

Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Background: Pregnancy and HIV affect CD4+ T lymphocytes and impact performance of QuantiFERON-TB Gold (QFT). We compared the results of QFT with QuantiFERON-TB Gold Plus (QFT-Plus), which also measures CD8+ responses to TB antigens, during pregnancy and ...
Vandana Kulkarni, Mallika Alexander, Ramesh Bhosale, Divyashri Jain, Prasad Deshpande, Emily Shira Gitlin, Arthi Vaidyanathan, Andrea Chalem, Shilpa Naik, Nikhil Gupte, Neelu Nawani, Amita Gupta, Jyoti Mathad   +12 more
doaj   +1 more source

IFN‐γ Levels and Indeterminate Rate: Comparative Analysis of Three Commercial Interferon‐Gamma Release Assays for Diagnosis of Mycobacterium tuberculosis Infection

Advances in Public Health, Volume 2026, Issue 1, 2026.
Background The diagnosis of Mycobacterium tuberculosis infection increasingly relies on interferon‐gamma release assay (IGRA) technologies. Despite their usefulness, inconsistency in IFN‐γ responses and the persistence of indeterminate results remain problematic across IGRA platforms.
Richard Kutame, Gifty Boateng, Vincent Gyau Boateng, Florence Agyemang-Bioh, Lorreta Antwi, Patricia Yankey, Valerie Lucy Naa Aku Vanderpuye, Joycelene Akua Attu, Baakwa De-graft Miah, Nathan Kofi Antwi, Alice Boakyewaa, Rexford Adade, Hannah Wesley   +12 more
wiley   +1 more source

Comparative performance evaluation of QIAreach QuantiFERON-TB and tuberculin skin test for diagnosis of tuberculosis infection in Viet Nam

Scientific Reports, 2023
Current WHO-recommended diagnostic tools for tuberculosis infection (TBI) have well-known limitations and viable alternatives are urgently needed. We compared the diagnostic performance and accuracy of the novel QIAreach QuantiFERON-TB assay (QIAreach ...
Luan Nguyen Quang Vo, Thi Thu Phuong Tran, Hai Quang Pham, Han Thi Nguyen, Ha Thu Doan, Huyen Thanh Truong, Hoa Binh Nguyen, Hung Van Nguyen, Hai Thanh Pham, Thuy Thi Thu Dong, Andrew Codlin, Rachel Forse, Tuan Huy Mac, Nhung Viet Nguyen   +13 more
doaj   +1 more source

Cutaneous Tuberculosis Presenting as a Chronic Dermatologic Disorder

Case Reports in Dermatological Medicine, Volume 2026, Issue 1, 2026.
Cutaneous tuberculosis (CTB) is a rare manifestation of extrapulmonary tuberculosis that is frequently misdiagnosed due to its diverse clinical presentation and resemblance to other dermatological conditions. Tuberculosis verrucosa cutis (TBVC), one clinical manifestation of CTB, poses a particular diagnostic challenge, as lesions are often ...
Olivia Spina, Henry Fraimow, Justin Green, Ioannis D. Bassukas   +3 more
wiley   +1 more source

Screening of household contacts for TB infection in Cote d'Ivoire

IJTLD Open
SETTING: Côte d'Ivoire is a country with a high incidence of TB. The control of TB infection is focused on high-risk patients but has limited implementation. OBJECTIVE: Cost-benefit analysis of TB infection (TBI) screening of household contacts in Côte d’
R. K. N’Guessan, D. A. B. Orsot, J.M. Ahui Brou, N. K. Bamba, M. E. Tchoutedjem Mefo, A. S. Bakayoko   +5 more
doaj   +1 more source

Biomarkers in QuantiFERON Supernatants May Help Distinguish Latent Tuberculosis Infection From Active Tuberculosis: Preliminary Report

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Latent tuberculosis infection (LTBI) is an important public health problem and a major source of future active tuberculosis (ATB) cases. In this preliminary study, we sought to identify host biomarkers that could potential differentiate between LTBI and ATB. Methods A total of 145 plasma samples obtained from antigen tubes of the QuantiFERON‐
Dagmara Borkowska-Tatar, Anna Zabost, Michał Czopowicz, Ewa Augustynowicz-Kopeć, Helioswilton Sales-Campos   +4 more
wiley   +1 more source

Prevalence, incidence and determinants of QuantiFERONTM positivity in South African schoolchildren

IJTLD Open
BACKGROUND: TB control requires the understanding and disruption of TB transmission. We describe prevalence, incidence and risk factors associated with childhood TB infection in Cape Town, South Africa.
J. Stewart, N. Walker, K. Jennings, C. Delport, J Nuttall, A.K. Coussens, R Dyers, D.A. Jolliffe, J.C.Y. Tang, W.D. Fraser, R.J. Wilkinson, L.-G. Bekker, A.R. Martineau, K. Middelkoop   +13 more
doaj   +1 more source

Accuracy of QuantiFERON-TB Gold Plus Test for Diagnosis of Mycobacterium tuberculosis Infection in Children

Journal of Clinical Microbiology, 2020
Compared to its predecessor QuantiFERON-TB Gold In Tube (QFT-IT), QuantiFERON-TB Gold Plus (QFT-Plus) contains an additional antigen tube (TB2), stimulating both CD4 + and CD8 + T cells. The ability to discriminate CD4 + and CD8 + responses is ...
Buonsenso, Danilo, Delogu, Giovanni, Perricone, Clelia, Grossi, Roberta, Careddu, Angela, De Maio, Flavio, Palucci, Ivana, Sanguinetti, Maurizio, Valentini, Piero, Sali, Michela   +9 more
openaire   +4 more sources

A Case of Advanced Urothelial Carcinoma Requiring Treatment Following a Positive Interferon‐Gamma Release Assay Prior to Avelumab Administration

IJU Case Reports, Volume 8, Issue 5, Page 454-457, September 2025.
ABSTRACT Introduction The association between the risk of latent tuberculosis infection (LTBI) reactivation and immune checkpoint inhibitor (ICI) administration has been reported. Case Presentation A man in his seventies underwent robot‐assisted laparoscopic radical cystectomy with ileal conduit diversion for muscle‐invasive bladder cancer. Three years
Yukiya Odagiri, Yoshiki Hiyama, Umi Ishida, Naotaka Nishiyama, Yoshihiro Yamamoto, Hiroshi Kitamura   +5 more
wiley   +1 more source