Results 61 to 70 of about 2,328 (144)
The objective: to compare results of six tests for immunological diagnosis of tuberculosis infection (TBI): intradermal tests (Mantoux with 2 TU PPD-L; test with tuberculous recombinant allergen (Diaskintest)) and IGRA laboratory tests (T-SPOT®.
A. A. Gordeev +7 more
doaj +1 more source
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine +24 more
wiley +1 more source
We report a rare presentation of Lemierre's syndrome in a 65‐year‐old woman, characterised by the coexistence of septic pulmonary emboli and pulmonary arterial thromboembolism, both documented on CT pulmonary angiography. ABSTRACT Lemierre syndrome (LS) is a rapidly progressing disease characterised by a recent oropharyngeal infection, complicated by ...
Antonio Fabozzi +5 more
wiley +1 more source
Dear Editor, About one-third of the human population is presently infected by Mycobacterium tuberculosis, and about 10% during their life develop active tuberculosis (TB) (5% during the first 2 years following infection)...
Wagdy Amin +10 more
doaj +1 more source
The Recent Development in the Diagnosis of Mycobacterium tuberculosis
Mycobacterium tuberculosis (MTB) remains a major global health challenge due to slow, low‐sensitivity traditional diagnostics. Rapid, highly sensitive point‐of‐care tests are critical for timely diagnosis and treatment, reducing transmission. This study reviews the evolution of MTB diagnostic tests, emphasizing advancements and addressing accessibility
Nimet Temur +8 more
wiley +1 more source
Introduction: Tuberculosis infection (TBI) is diagnosed based on a positive immune response to M. tuberculosis antigens. This study aimed to evaluate both the qualitative and quantitative performance of two novel IGRA-based tests, the STANDARD E TB-Feron
Valeriu Crudu +6 more
doaj +1 more source
AbstractPerformance of interferon-γ (IFN-γ) release assays still needs to be improved. The data on the performance of QuantiFERON-TB Gold Plus (QFT-Plus), a new-generation of QFT assay are limited. This study evaluated the diagnostic performance of QFT-Plus, and compared to that of QuantiFERON-TB Gold In-Tube (QFT-GIT).
Lina Yi +14 more
openaire +2 more sources
High Mycobacterium bovis Exposure but Low IGRA Positivity in UK Farm Workers
ABSTRACT Background Between 1999 and 2021, 505 culture‐confirmed cases of M. bovis disease in humans (zoonotic tuberculosis, TB) were diagnosed in England. We aimed to estimate the prevalence of M. bovis infection in persons exposed to TB‐infected cattle in England and identify any risk factors associated with latent TB infection (LTBI) in this ...
Amy Thomas +18 more
wiley +1 more source
Interferon Gamma Release Assays in active Tuberculosis: new medical insights
Since first presentation, Interferon γ Release Assays (IGRAs) have had basic and wide application to LTBI, in accordance with international consensus and CDC recommendations, leaving their use in active TB to the field of study and research.We reviewed ...
Sandro Pierdomenico +4 more
doaj +1 more source
Characterization of the CD4 and CD8 T-cell response in the QuantiFERON-TB Gold Plus kit
QuantiFERON-TB Gold In-Tube (QFT-GIT, Qiagen, Hilden, Germany) is an interferon-γ (IFN-γ) release assay designed to detect latent tuberculosis infection (LTBI). Although QFT-GIT has several advantages (mainly that it is not affected by the Bacille Calmette-Guérin vaccination), it has a poor sensitivity in immune-compromised individuals as it involves ...
Lucia Barcellini +10 more
openaire +4 more sources

