Results 31 to 40 of about 1,955,704 (153)

Evaluating the diagnostic accuracy of QIAreach QuantiFERON-TB compared to QuantiFERON-TB Gold Plus for tuberculosis: a systematic review and meta-analysis

Scientific Reports
Accurate tuberculosis (TB) diagnosis remains challenging, especially in resource-limited settings. This study aims to assess the diagnostic performance of the QIAreach QuantiFERON-TB (QFT) assay, with a specific focus on comparing its diagnostic ...
Shima Mahmoudi, Sadra Nourazar
doaj   +2 more sources

Commentary on: diagnostic accuracy and predictive value of the QuantiFERON-TB Gold Plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study. [PDF]

Lancet Reg Health Eur
Mycobacterium tuberculosis is an ancient pathogen that continues to pose a major public health threat, with >10 million cases of active TB leading to an estimated 1.25 million deaths worldwide in 2023.
Allen V, Galloway J.
europepmc   +2 more sources

Low concordance between QIAreach QuantiFERON-TB, a novel interferon-gamma release assay, and QuantiFERON-TB Gold Plus, in a population-based survey in Blantyre, Malawi

Journal of Clinical Microbiology
Urgent improvements in the diagnosis and management of Mycobacterium tuberculosis infection are required to reach End TB goals. Conventional interferon-gamma release assays (IGRAs), such as QuantiFERON-TB Gold Plus (QFT-Plus), require substantial ...
Hannah M. Rickman, Mphatso D. Phiri, Hannah Mbale, Katherine C. Horton, Marc Y. R. Henrion, Emily S. Nightingale, James A. Seddon, Elizabeth L. Corbett, Peter MacPherson   +8 more
doaj   +2 more sources

Refining the diagnostic approach to latent tuberculosis Infection with Quantiferon gold plus: A retrospective analysis of borderline results. [PDF]

PLoS One
The Quantiferon Gold Plus (QFT) test, a widely used interferon-γ release assay (IGRA), diagnoses latent tuberculosis infection (LTBI) with a positivity threshold of ≥0.35 IU/mL. Results near this cut-off can be challenging to interpret due to variability
Ruedas-López A, Herrero-Martínez JM, Reyes A, González-Blanco B, López-Roa P.   +4 more
europepmc   +2 more sources

Comparing QuantiFERON-TB Gold Plus with QuantiFERON-TB Gold in-tube for diagnosis of latent tuberculosis infection among highly TB exposed gold miners in South Africa [version 3; peer review: 2 approved, 1 approved with reservations]

Gates Open Research, 2022
Background: QuantiFERON-TB-Gold-in-tube (QFT-GIT) is an interferon-gamma release assay (IGRA) used to diagnose latent tuberculosis infection. Limited data exists on performance of QuantiFERON-TB Gold-Plus (QFT-Plus), a next generation of IGRA that ...
Alison D. Grant, Thobani Ntshiqa, Raoul Mansukhani, Violet Chihota, Kavindhran Velen, Salome Charalambous, Lindiwe Nhlangulela, Thomas R. Hawn, Pholo Maenetje, Gavin Churchyard, Katherine Fielding, Robert Wallis   +11 more
doaj   +1 more source

Retrospective Performance Analyses of over Two Million U.S. QuantiFERON Blood Sample Results

Microbiology Spectrum, 2021
Both the QuantiFERON-TB Gold Plus (QFT-Plus) and the QuantiFERON-TB Gold In-Tube (QFT-GIT) tests are interferon gamma (IFN-γ) release assays (IGRAs) intended to detect in vitro cell-mediated immune responses to Mycobacterium tuberculosis antigens.
Caixia Bi, Richard B. Clark, Ronald Master, Hema Kapoor, Martin H. Kroll, Ann E. Salm, William A. Meyer   +6 more
doaj   +1 more source

Predicting stringent QuantiFERON-TB Gold Plus conversions in contacts of tuberculosis patients

Journal of Microbiology, Immunology and Infection, 2023
Objectives: To assess associations between disease severity in index TB patients and QuantiFERON-TB Gold Plus (QFT-Plus) results in contacts, and predictors for QFT-Plus conversion in contacts over 6–12 months.
Sheng-Wei Pan, Donald G. Catanzaro, Marva Seifert, Rehan R. Syed, Naomi Hillery, Mei-Lin Ho, Valeriu Crudu, Elena Tudor, Nelly Ciobanu, Alexandru Codreanu, Antonino Catanzaro, Timothy C. Rodwell   +11 more
doaj   +1 more source

QuantiFERON-TB Gold PLUS versus QuantiFERON-TB Gold In-Tube test for diagnosing tuberculosis infection [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims QuantiFERON-TB Gold PLUS (QFT-PLUS) was developed as a new version of the interferon-γ (IFN-γ) release assay that contains an extra antigen tube to elicit a CD8+ T-cell response in addition to a CD4+ T-cell response.
Soo Han Kim, Kyung-Wook Jo, Tae Sun Shim
doaj   +1 more source

First clinical evaluation of the QIAreachTM QuantiFERON-TB for tuberculosis infection and active pulmonary disease

Pulmonology, 2022
Objective: 1) to compare the QIAreachTM QuantiFERON-TB (QIAreach QFT) vs. QuantiFERON®-TB Gold Plus assay (QFT-Plus) to detect tuberculosis (TB) infection; 2) to evaluate diagnostic sensitivity of QIAreach QFT using active TB as surrogate for TB ...
K. Fukushima, K. Akagi, A. Kondo, T. Kubo, N. Sakamoto, H. Mukae   +5 more
doaj   +3 more sources

Comparing the Diagnostic Performance of QFT-Plus to Other Tests of Latent Tuberculosis Infection: A Systematic Review and Meta-analysis.

Clinical Infectious Diseases, 2020
BACKGROUND We conducted this review to compare the sensitivity, specificity, reproducibility, and predictive ability of QFT-Plus with that of QFT-GIT (QIAGEN, Hilden, Germany), T-SPOT.TB (Oxford Immunotec, Oxford, United Kingdom) and the tuberculin skin ...
C. Oh, E. Ortiz-Brizuela, M. Bastos, D. Menzies   +3 more
semanticscholar   +1 more source