Results 51 to 60 of about 1,907 (170)

In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma Production

Life, 2022
Increased rates of indeterminate QuantiFERON-TB Gold Plus Assay (QFT-Plus) were demonstrated in patients hospitalized with Coronavirus Disease (COVID)-19.
Alessandra Imeneo, Grazia Alessio, Andrea Di Lorenzo, Laura Campogiani, Alessandra Lodi, Filippo Barreca, Marta Zordan, Virginia Barchi, Barbara Massa, Simona Tedde, Angela Crea, Pietro Vitale, Ilaria Spalliera, Mirko Compagno, Luigi Coppola, Luca Dori, Vincenzo Malagnino, Elisabetta Teti, Massimo Andreoni, Loredana Sarmati, Marco Iannetta   +20 more
doaj   +1 more source

Uloga testova koji otpuštaju interferon gama u dijagnostici latentne tuberkuloze u djece [PDF]

, 2023
Despite numerous published papers, diagnosis of latent tuberculosis infection (LTBI) in children is still an undefined area. The importance of this topic lies in the fact that one third of the world’s population is infected with Mycobacterium (M ...
Mihatov Štefanović, Iva, Pavić, Ivan, Šegović, Mateja   +2 more
core   +2 more sources

The Pitfalls of Mining for QuantiFERON Gold in Severely Ill Patients With COVID-19

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2022
Objective: To assess the proportion of indeterminate QuantiFERON-TB Gold Plus (QFT-Plus) results in patients admitted for severe coronavirus disease 2019 (COVID-19) pneumonia and evaluate the factors associated with indeterminate QFT-Plus results ...
Melissa P. Cortes, MD, Carrie S. Schultz, PA-C, MS, Shahin Isha, MBBS, Jorge E. Sinclair, MD, Shivang Bhakta, MD, Katie L. Kunze, PhD, MA, Patrick W. Johnson, BS, Jennifer B. Cowart, MD, Rickey E. Carter, PhD, Pablo Moreno Franco, MD, Devang K. Sanghavi, MBBS, MD, Archana Roy, MD   +11 more
doaj   +1 more source

Sensitivity and characteristics associated with positive QuantiFERON-TB Gold-Plus assay in children with confirmed tuberculosis.

PLoS ONE, 2019
BACKGROUND:Although QuantiFERON-TB Gold Plus (QFT-Plus), a new interferon-gamma release assay, has shown good performance in adults, little data is available in children. METHODS:De-identified data from TB-suspected patients age
Duc T Nguyen, Ha Phan, Trang Trinh, Hang Nguyen, Ha Doan, Nam Pham, Hung Nguyen, Hanh Nguyen, Hung V Nguyen, Hoi V Le, Nhung Nguyen, Edward A Graviss   +11 more
doaj   +1 more source

Vitamin D supplementation to prevent tuberculosis infection in South African schoolchildren: multicenter phase 3 double-blind randomized placebo-controlled trial (ViDiKids)

International Journal of Infectious Diseases, 2023
: Objectives: To determine whether weekly oral supplementation with 10,000 IU vitamin D3 for 3 years reduces the risk of sensitization to M. tuberculosis in South African schoolchildren aged 6-11 years with negative QuantiFERON-tuberculosis (TB) Gold ...
Keren Middelkoop, Justine Stewart, Neil Walker, Carmen Delport, David A. Jolliffe, Anna K. Coussens, James Nuttall, Jonathan C.Y. Tang, William D. Fraser, Christopher J. Griffiths, Geeta Trilok Kumar, Suzanne Filteau, Richard L. Hooper, Robert J. Wilkinson, Linda-Gail Bekker, Adrian R. Martineau   +15 more
doaj   +1 more source

Mycobacterium tuberculosis Immune Response in Patients With Immune-Mediated Inflammatory Disease [PDF]

, 2021
Subjects with immune-mediated inflammatory diseases (IMID), such as rheumatoid arthritis (RA), have an intrinsic higher probability to develop active-tuberculosis (TB) compared to the general population. The risk ranges from 2.0 to 8.9 in RA patients not
Caccamo N., Cantini F., Chiacchio T., Cuzzi G., Farroni C., Goletti D., Guggino G., Lo Pizzo M., Massafra U., Navarra A., Palmieri F., Petrone L., Petruccioli E., Vanini V.   +13 more
core   +1 more source

Association of TAP1 1177A>G and 2090A>G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study [PDF]

, 2021
Latent tuberculosis infection (LTBI) is a condition that has no clinical signs and symptoms. LTBI patients are characterized by persistent immune responses to Mycobacterium tuberculosis, and approximately 5-10% of these infected individuals will develop ...
Bacilio-Medrano, Eva Adriana, Cazarez-Navarro, Gerardo, Hernández-Cañaveral , Iván Isidro, Huerta-Olvera , Selene, Martínez-López , Erika, Palomares-Marín, Jaime, Pereira-Suárez, Ana Laura, Rodríguez-Preciado , Sergio Yair   +7 more
core   +2 more sources

Prevalence of latent tuberculosis infection among foreign students in Lübeck, Germany tested with QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus

Journal of Occupational Medicine and Toxicology, 2017
Background The tuberculosis (TB) incidence rate in foreign-born individuals has been increasing in Germany in recent years. Foreign students may be an important source of latent tuberculosis infection (LTBI) in low-incidence countries.
Elia Noemi Gallegos Morales, Johannes Knierer, Anja Schablon, Albert Nienhaus, Jan Felix Kersten   +4 more
doaj   +1 more source

The sensitivity of the QuantiFERON®-TB Gold Plus assay in Zambian adults with active tuberculosis. [PDF]

, 2017
SETTING AND OBJECTIVE: To investigate the sensitivity of the new interferon-gamma release assay (IGRA), QuantiFERON®-TB Gold Plus (QFT-Plus), for active TB (used as a surrogate for latent tuberculous infection) in a Zambian TB clinic. DESIGN: Consecutive
Amofa-Sekyi, M, Ayles, H, Bailey, S-L, Cheeba-Lengwe, M, Chiwele, K, Floyd, S, Kaluba-Milimo, D, Kosloff, B, Maluzi, K, Telisinghe, L   +9 more
core   +1 more source

Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Background: Pregnancy and HIV affect CD4+ T lymphocytes and impact performance of QuantiFERON-TB Gold (QFT). We compared the results of QFT with QuantiFERON-TB Gold Plus (QFT-Plus), which also measures CD8+ responses to TB antigens, during pregnancy and ...
Vandana Kulkarni, Mallika Alexander, Ramesh Bhosale, Divyashri Jain, Prasad Deshpande, Emily Shira Gitlin, Arthi Vaidyanathan, Andrea Chalem, Shilpa Naik, Nikhil Gupte, Neelu Nawani, Amita Gupta, Jyoti Mathad   +12 more
doaj   +1 more source