A cost-effectiveness evaluation of methods for screening for TB infection in patients with diabetes mellitus [PDF]
BACKGROUND: Globally, 10.6 million TB cases occurred in 2021. Malaysia reported 25,000 TB cases in 2022, and also has a high prevalence of diabetes mellitus (DM), amplifying TB risks.
M.I. Mahmood +4 more
doaj +2 more sources
A detailed analysis of borderline results in the QuantiFERON-TB Gold-Plus assay incorporating longitudinal follow-up: intermediate-burden setting. [PDF]
The QuantiFERON-TB Gold Plus (QFT-Plus; Qiagen, Hilden, Germany) assay is widely used for latent TB infection (LTBI) screening; however, borderline results often show variability during follow-up.
Shin E +6 more
europepmc +2 more sources
Immune Sensitization to Mycobacterium tuberculosis Among Young Children with and without Tuberculosis [PDF]
Identification of young children with Mycobacterium tuberculosis (Mtb) infection is critical to curb pediatric morbidity and mortality. The optimal test to identify young children with Mtb infection remains controversial.
Jesús Gutierrez +12 more
doaj +2 more sources
Comparison of Rifampin and Isoniazid for Latent Tuberculosis Infection in Kidney Transplant Candidates: Focus on Tolerability and Treatment Completion. [PDF]
This study comparing 4‐month rifampin with 9‐month isoniazid for latent tuberculosis in kidney transplant candidates showed higher treatment completion rates and no transaminase elevations in the rifampin group. However, some patients experienced an increase in blood pressure while taking antihypertensive medications known to interact with rifampin ...
Simkins J +13 more
europepmc +2 more sources
Introduction: The optimal frequency of rescreening for latent tuberculosis infection (LTBI) in patients with inflammatory arthritis on biologic/targeted-synthetic disease modifying anti-rheumatic drugs (b/ts-DMARDs) is uncertain.
Zehra Ozsoy +11 more
doaj +2 more sources
Tuberculosis (TB) remains a global public health problem. The determination of tuberculosis infection (TBI) using interferon-gamma release assay has now been used widely.
Dewi Kartika Turbawaty +11 more
doaj +2 more sources
Evaluation of QIAreach QuantiFERON-TB lateral-flow nanoparticle fluorescence assay for TB infection diagnosis among TB household contacts in three high-burden settings. [PDF]
BackgroundTuberculosis infection (TBI) testing, and treatment are fundamental to achieve TB elimination. TBI testing among close or household contacts (HHCs) has been limited, in part due to perceived complexity and high operational cost.
Thobani Ntshiqa +22 more
doaj +2 more sources
Optimizing tuberculosis infection screening strategies for people living with HIV in Thailand: a cost-effectiveness analysis [PDF]
Background To support evidence-based decision-making in Thailand, we assessed the cost-effectiveness of QuantiFERON-TB Gold Plus (QFT-Plus) compared to the Tuberculin Skin Test (TST) in people living with HIV (PLWH).
Nuntana Chumpa +2 more
doaj +2 more sources
One quarter of the world's population is estimated to be infected with Mycobacterium tuberculosis. Identifying recent TB infection (TBI) offers an avenue to targeted TB preventative therapy provision, and prevention to disease progression.
Modupe Amofa-Sekyi +15 more
doaj +2 more sources
Summary To our knowledge, this is the first head-to-head study to evaluate QuantiFERON-TB Gold Plus, QuantiFERON-TB Gold In-Tube, ESAT6-CFP10, and tuberculin skin test among adolescents.
Peng Lu +9 more
doaj +2 more sources

