Results 21 to 30 of about 1,484 (134)

Retrospective Performance Analyses of over Two Million U.S. QuantiFERON Blood Sample Results

Microbiology Spectrum, 2021
Both the QuantiFERON-TB Gold Plus (QFT-Plus) and the QuantiFERON-TB Gold In-Tube (QFT-GIT) tests are interferon gamma (IFN-γ) release assays (IGRAs) intended to detect in vitro cell-mediated immune responses to Mycobacterium tuberculosis antigens.
Caixia Bi, Richard B. Clark, Ronald Master, Hema Kapoor, Martin H. Kroll, Ann E. Salm, William A. Meyer   +6 more
doaj   +1 more source

Predicting stringent QuantiFERON-TB Gold Plus conversions in contacts of tuberculosis patients

Journal of Microbiology, Immunology and Infection, 2023
Objectives: To assess associations between disease severity in index TB patients and QuantiFERON-TB Gold Plus (QFT-Plus) results in contacts, and predictors for QFT-Plus conversion in contacts over 6–12 months.
Sheng-Wei Pan, Donald G. Catanzaro, Marva Seifert, Rehan R. Syed, Naomi Hillery, Mei-Lin Ho, Valeriu Crudu, Elena Tudor, Nelly Ciobanu, Alexandru Codreanu, Antonino Catanzaro, Timothy C. Rodwell   +11 more
doaj   +1 more source

QuantiFERON-TB Gold PLUS versus QuantiFERON-TB Gold In-Tube test for diagnosing tuberculosis infection [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims QuantiFERON-TB Gold PLUS (QFT-PLUS) was developed as a new version of the interferon-γ (IFN-γ) release assay that contains an extra antigen tube to elicit a CD8+ T-cell response in addition to a CD4+ T-cell response.
Soo Han Kim, Kyung-Wook Jo, Tae Sun Shim
doaj   +1 more source

First clinical evaluation of the QIAreachTM QuantiFERON-TB for tuberculosis infection and active pulmonary disease

Pulmonology, 2022
Objective: 1) to compare the QIAreachTM QuantiFERON-TB (QIAreach QFT) vs. QuantiFERON®-TB Gold Plus assay (QFT-Plus) to detect tuberculosis (TB) infection; 2) to evaluate diagnostic sensitivity of QIAreach QFT using active TB as surrogate for TB ...
K. Fukushima, K. Akagi, A. Kondo, T. Kubo, N. Sakamoto, H. Mukae   +5 more
doaj   +3 more sources

P164 Qft-plus: do the peptides in the tb2 tube induce a t suppressor response in some subjects? [PDF]

Early detection and screening in TB, 2017
Introduction The revised QuantiFERON-TB Gold assay (QFT-Plus) has an extra tube (TB2), containing peptides thought to stimulate CD8 +T cells; TB7 antigen is no longer included. The test is designed to detect latent tuberculosis infection. Hypothesis Levels of interferon-γ in TB2 should always be greater than TB1 Methods QFT-Plus was used routinely
M Sieren, B Thippeswamy, C Mandiveyi, N Marshall, G Bothamley   +4 more
openaire   +1 more source

Comparison of the change in QuantiFERON-TB Gold Plus and QuantiFERON-TB Gold In-Tube results after preventive therapy for latent tuberculosis infection.

PLoS ONE, 2020
BackgroundWe investigated changes in the interferon-γ levels before and after treatment of latent tuberculosis infection (LTBI) using QuantiFERON-TB Gold Plus (QFT-Plus) and QuantiFERON-TB Gold In-Tube (QFT-GIT) assays.
Ock-Hwa Kim, Kyung-Wook Jo, Shinhee Park, Yong-Ha Jo, Mi-Na Kim, Heungsup Sung, Tae Sun Shim   +6 more
doaj   +1 more source

Comparative evaluation of QuantiFERON-TB Gold Plus for diagnosis of latent tuberculosis infection during solid organ transplantation

Korean Journal of Transplantation, 2020
Background : The diagnosis of latent tuberculosis infection (LTBI) in solid organ transplantation (SOT) patients under lifelong immunosuppression has profound effects on preoperative and postoperative management.
Sun Joo Yoon, Won Kyung Kwon, Mi Jeong Jeong, Jinyoung Lee, Ha Young Oh, Wooseong Huh, Hye Ryoun Jang, Jae-Won Joh, Jong Man Kim, Gyu-Seong Choi, Sung Joo Kim, Jae Berm Park, Kyo Won Lee, Dong Hyun Sinn, Jin-Oh Choi, Eun-Suk Kang   +15 more
doaj   +1 more source

Comparison of Rifampin and Isoniazid for Latent Tuberculosis Infection in Kidney Transplant Candidates: Focus on Tolerability and Treatment Completion. [PDF]

Transpl Infect Dis
This study comparing 4‐month rifampin with 9‐month isoniazid for latent tuberculosis in kidney transplant candidates showed higher treatment completion rates and no transaminase elevations in the rifampin group. However, some patients experienced an increase in blood pressure while taking antihypertensive medications known to interact with rifampin ...
Simkins J, Viotti JB, Natori Y, Anjan S, Mattiazzi A, Ortigosa-Goggins M, Guerra G, Roth D, Kupin W, Pagan JA, Cabeza F, Ciancio G, Morsi M, Morris MI.   +13 more
europepmc   +2 more sources

Evaluation of a new interferon gamma release assay, in comparison to tuberculin skin tests and quantiferon tuberculosis goldplus for the detection of latent tuberculosis infection in children from a high tuberculosis burden setting

International Journal of Mycobacteriology, 2021
Background: Detection of latent tuberculosis infection (LTBI) in children, exposed to tuberculosis (TB) infections, followed by appropriate treatment, could be instrumental in reducing TB burden.
Kirtilaxmi Benachinmardi, Sangeetha Sampath, Mohan Rao   +2 more
doaj   +1 more source

Performance of T-Track^® TB, a Novel Dual Marker RT-qPCR-Based Whole-Blood Test for Improved Detection of Active Tuberculosis

Diagnostics, 2023
Tuberculosis (TB) is one of the leading causes of death by an infectious disease. It remains a major health burden worldwide, in part due to misdiagnosis.
Johannes P. Meier, Selina Möbus, Florian Heigl, Alexandra Asbach-Nitzsche, Hans Helmut Niller, Annelie Plentz, Korkut Avsar, Marion Heiß-Neumann, Bernhard Schaaf, Uwe Cassens, Bernd Seese, Daniel Teschner, Sabin Handzhiev, Uwe Graf, Christoph Lübbert, Monika Steinmaurer, Konstantina Kontogianni, Christoph Berg, Andreas Maieron, Stefan H. Blaas, Ralf Wagner, Ludwig Deml, Sascha Barabas   +22 more
doaj   +1 more source