Results 61 to 70 of about 21,986 (186)

Machine learning model based on SERPING1, C1QB, and C1QC: A novel diagnostic approach for latent tuberculosis infection

open access: yesiLABMED, Volume 2, Issue 4, Page 248-265, December 2024.
Latent tuberculosis infection (LTBI) is an important source of active tuberculosis (ATB), but there is currently a lack of effective diagnostic tools to distinguish ATB from LTBI. In this study, by integrating transcriptome data analysis, a machine learning algorithm and protein interaction network analysis, an LTBI diagnosis model based on SERPING1 ...
Linsheng Li   +7 more
wiley   +1 more source

Factors associated with positive TST and /or QFT-GIT assays.

open access: yes, 2018
Factors associated with positive TST and /or QFT-GIT assays.
Nikhil Gupte (189999)   +20 more
core   +1 more source

Aqueous extract‐mediated green synthesis of CuO nanoparticles: Potential anti‐tuberculosis agents

open access: yesFood Science &Nutrition, Volume 12, Issue 8, Page 5907-5921, August 2024.
In sum, the mixture of garlic extract and nanoparticles at 100 mg/kg body weight of rats inhibited tuberculosis infection. It exhibited antibacterial activity and antioxidant properties in lung tissue and prevented lung damage. The results are promising and show that garlic extract and nanoparticles can be utilized to prevent tuberculosis.
Zohreh Zamanian   +3 more
wiley   +1 more source

Accurate diagnosis of latent tuberculosis in children, people who are immunocompromised or at risk from immunosuppression and recent arrivals from countries with a high incidence of tuberculosis: systematic review and economic evaluation

open access: yes, 2016
Background - Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB) [(Zopf 1883) Lehmann and Neumann 1896], is a major cause of morbidity and mortality. Nearly one-third of the world’s population is infected with MTB; TB has an annual incidence of
Seedat, Farah   +28 more
core   +2 more sources

The Clinical Usefulness of Tuberculin Skin Test versus Interferon-Gamma Release Assays for Diagnosis of Latent Tuberculosis in HIV Patients: A Meta-Analysis. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:Accurate diagnosis of latent tuberculosis infection (LTBI) is becoming increasingly concerning due to the increasing the HIV epidemic, which have increased the risk for reactivation to active tuberculosis (TB) infection.
Erfan Ayubi   +5 more
doaj   +1 more source

Utility of the interferon-gamma release assay for latent tuberculosis infection screening among indian health-care workers

open access: yesIndian Journal of Community Medicine, 2021
Background: The utility of interferon-gamma release assays (IGRAs) for latent tuberculosis infection (LTBI) screening among health-care workers (HCWs) in low- and middle-income countries (LMICs) remains unclear.
Sunita Girish   +14 more
doaj   +1 more source

Revisiting Bacille Calmette‐Guérin revaccination strategies: timing of immunization, Mycobacterium tuberculosis and non‐tuberculous mycobacteria infections, strain potency and standardization of randomized controlled trials

open access: yesClinical and Translational Discovery, Volume 4, Issue 3, June 2024.
1) Bacille Calmette‐Guérin (BCG) revaccination timing is crucial for enhancing immunity, particularly in adolescents and young adults. 2) Prior Mycobacterium tuberculosis or non‐tuberculous mycobacteria infections may influence the perceived efficacy of BCG revaccination.
Wenping Gong   +4 more
wiley   +1 more source

Prevalence of latent tuberculosis infection in Asian nations: A systematic review and meta‐analysis

open access: yesImmunity, Inflammation and Disease, Volume 12, Issue 2, February 2024.
Abstract Background Tuberculosis (TB) is a serious public health concern around the world including Asia. TB burden is high in Asian countries and significant population harbor latent tuberculosis infection(LTBI). Aim This systematic review and meta‐analysis aims to evaluate the prevalence of LTBI in Asian countries.
Abhigan B. Shrestha   +14 more
wiley   +1 more source

Analysis of cellular and soluble profiles in QuantiFERON nonconverters, converters, and reverters in the Gambia

open access: yesImmunity, Inflammation and Disease, Volume 7, Issue 4, Page 260-270, December 2019., 2019
Here we show immunological factors contributing to QFT conversion and reversion. Our findings provide insight into mechanisms underlying ‘resistance’ to Mycobacterium tuberculosis which could be harnessed for novel immune‐based therapeutics. Abstract Background Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide ...
Lydia Medawar   +5 more
wiley   +1 more source

Diagnostic values of the QFT-GIT and TST for active tuberculosis assessed in PTB patients and disease controls.

open access: yes, 2015
Footnotes: % Sensitivity: percentage of positive, calculated with available QFT-GIT and TST results; 95% CI: Confidence interval; % Specificity: percentage of negative, calculated with available QFT-GIT and TST results; PPV, positive predictive value ...
Hui Xia (133168)   +7 more
core   +1 more source

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