Results 51 to 60 of about 2,044 (173)

Role of Quantiferon gold assay in the detection and follow-up of treatment of latent tuberculosis infection in some acquired immune-compromised patients

Egyptian Journal of Chest Disease and Tuberculosis, 2019
Background In patients latently infected with Mycobacterium tuberculosis, immunosuppression increases the risk of progression to active tuberculosis (TB), which is still considered one of the difficult and frequent opportunistic infections worldwide ...
Emad A Korra, Ibrahim A Dwedar, Eman B AbdelFattah, Azza H Hassan   +3 more
doaj   +1 more source

Cost-effectiveness of Quantiferon®-TB Gold-in-Tube versus tuberculin skin testing for contact screening and treatment of latent tuberculosis infection in Brazil. [PDF]

PLoS ONE, 2013
Latent tuberculosis infection (LTBI) is a reservoir for new TB cases. Isoniazid preventive therapy (IPT) reduces the risk of active TB by as much as 90%, but LTBI screening has limitations.
Ricardo Ewbank Steffen, Rosângela Caetano, Márcia Pinto, Diogo Chaves, Rossini Ferrari, Mayara Bastos, Sandra Teixeira de Abreu, Dick Menzies, Anete Trajman   +8 more
doaj   +1 more source

Comparing interferon-gamma release assays with tuberculin skin test for identifying latent tuberculosis infection that progresses to active tuberculosis : systematic review and meta-analysis [PDF]

, 2017
Background Timely and accurate identification of people with latent tuberculosis infection (LTBI) is important for controlling Mycobacterium tuberculosis (TB). There is no gold standard for diagnosis of LTBI.
Auguste, Peter, Clarke, Aileen, Court, Rachel A., McCarthy, Noel D., Pink, Joshua, Sutcliffe, P. (Paul), Tsertsvadze, Alexander   +6 more
core   +3 more sources

확진된 소아청소년 결핵에서 인터페론감마 분비검사의 진단적 가치 [PDF]

, 2021
Purpose: This study aimed to evaluate the diagnostic value of the QuantiFERON-TB Gold In-Tube (QFT-GIT) in children with confirmed tuberculosis (TB). Methods: We retrospectively reviewed the medical records of children aged ≤18 years who underwent both ...
강지만, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균, 안종균   +43 more
core   +1 more source

Diagnostic performance of culture filtered protein 10‐specific perforin in pediatric patients with active tuberculosis

Journal of Clinical Laboratory Analysis, Volume 34, Issue 11, November 2020., 2020
Diagnostic efficacy of CFP10‐specific perforin for TB diagnosis was higher than T‐SPOT assay. CFP10‐specific perforin effectively distinguishes between ATB and LTBI. CFP10‐specific perforin can be secreted by CD4+ and CD8+ T cells. Abstract Background Mycobacterium tuberculosis (Mtb)‐specific perforin were significantly increased in patients with ...
Qinzhen Cai, Xin Shen, Hongze Li, Cong Yao, Na Sun, Jun Wang, Huan Wu, Chunhui Yuan, Jie Xiang, Yun Xiang   +9 more
wiley   +1 more source

Retrospective Performance Analyses of over Two Million U.S. QuantiFERON Blood Sample Results

Microbiology Spectrum, 2021
Both the QuantiFERON-TB Gold Plus (QFT-Plus) and the QuantiFERON-TB Gold In-Tube (QFT-GIT) tests are interferon gamma (IFN-γ) release assays (IGRAs) intended to detect in vitro cell-mediated immune responses to Mycobacterium tuberculosis antigens.
Caixia Bi, Richard B. Clark, Ronald Master, Hema Kapoor, Martin H. Kroll, Ann E. Salm, William A. Meyer   +6 more
doaj   +1 more source

A systematic review of economic models used to assess the cost-effectiveness of strategies for identifying latent tuberculosis in high-risk groups [PDF]

, 2016
Timely diagnosis and treatment of latent tuberculosis infection (LTBI) through screening remains a key public health priority. Although globally it is recommended to screen people at high risk of developing TB, the economic evidence underpinning these ...
Auguste, Peter, Court, Rachel A., Pink, Joshua, Tsertsvadze, Alexander   +3 more
core   +1 more source

How are high burden countries implementing policies and tools for latent tuberculosis infection? A survey of current practices and barriers

Health Science Reports, Volume 3, Issue 2, June 2020., 2020
Abstract Background and aims Despite the World Health Organization (WHO)'s updated guidelines on tuberculosis (TB) preventive treatment, the scale‐up of TB preventive therapy remains low in many high‐burden countries (HBCs). We conducted a survey to better understand the current status of policy implementation and barriers for scale‐up.
Lena Faust, Morten Ruhwald, Samuel Schumacher, Madhukar Pai   +3 more
wiley   +1 more source

Risk factors associated with positive QuantiFERON-TB Gold In-Tube and tuberculin skin tests results in Zambia and South Africa.

PLoS ONE, 2011
IntroductionThe utility of T-cell based interferon-gamma release assays for the diagnosis of latent tuberculosis infection remains unclear in settings with a high burden of tuberculosis.ObjectivesTo determine risk factors associated with positive ...
Kwame Shanaube, James Hargreaves, Katherine Fielding, Ab Schaap, Katherine-Anne Lawrence, Bernadette Hensen, Charalambos Sismanidis, Angela Menezes, Nulda Beyers, Helen Ayles, Peter Godfrey-Faussett   +10 more
doaj   +1 more source

Interferon-gamma release assay for screening of tuberculosis infection in children

BMC Infectious Diseases, 2023
Background Interferon-gamma release assay (IGRA) is the main tool for the diagnosis of latent tuberculosis (TB) infection (LTBI). However, the indeterminate results were more frequent in children, and the underlying reasons were largely speculative.
Huiwen Zheng, Jing Xiao, Feina Li, Hao Chen, Deze Li, Yonghong Wang, Yajie Guo, Yuying Chen, Chen Shen   +8 more
doaj   +1 more source