Results 11 to 20 of about 21,986 (186)

Programmatic impact of QuantiFERON-TB Gold In-Tube implementation on latent tuberculosis diagnosis and treatment in a public health clinic. [PDF]

open access: yesPLoS ONE, 2012
QuantiFERON-TB Gold In-Tube (QFT-GIT) is considered an alternative to the tuberculin skin test (TST) for the diagnosis of tuberculosis (TB) infection, but the programmatic impact of QFT-GIT implementation is largely unknown. In March, 2010, the Baltimore
Maunank Shah   +6 more
doaj   +1 more source

Fluctuating Behavior and Influential Factors in the Performance of the QuantiFERON-TB Gold In-Tube Assay in the Diagnosis of Tuberculosis. [PDF]

open access: yesPLoS ONE, 2015
The QuantiFERON-TB Gold In-Tube (QFT-GIT) is a newly developed but widely used interferon-γ release assay for diagnosing tuberculosis (TB). However, research has not determined whether age or the use of an immune suppressive or anti-TB treatment ...
Lei Bao   +7 more
doaj   +1 more source

Comparing QuantiFERON-TB Gold Plus with QuantiFERON-TB Gold in-tube for diagnosis of latent tuberculosis infection among highly TB exposed gold miners in South Africa [version 3; peer review: 2 approved, 1 approved with reservations]

open access: yesGates Open Research, 2022
Background: QuantiFERON-TB-Gold-in-tube (QFT-GIT) is an interferon-gamma release assay (IGRA) used to diagnose latent tuberculosis infection. Limited data exists on performance of QuantiFERON-TB Gold-Plus (QFT-Plus), a next generation of IGRA that ...
Alison D. Grant   +11 more
doaj   +1 more source

Evaluation of Interferon Gamma Release Assay in the Diagnosis of Active and ‎Latent Tuberculosis among Patients and Contacts ‎ [PDF]

open access: yesAfro-Egyptian Journal of Infectious and Endemic Diseases, 2021
Background and study aim: To date, tuberculosis (TB) is a global health emerging disease. Early detection of TB infection is critical to start therapy and stop increasing the prevalence of TB cases.
Heba Selim, Yousra El-Maradny
doaj   +1 more source

Prevalence of indeterminate tuberculosis interferon‐gamma release assays in COVID‐19 patients: Systematic review and meta‐analysis

open access: yesHealth Science Reports, Volume 6, Issue 12, December 2023., 2023
Abstract Background and Aims The reliability of interferon‐gamma‐release‐assays (IGRAs) for tuberculosis (TB) testing in coronavirus disease 2019 (COVID‐19) patients is unknown. This study aimed to systematically review the prevalence of indeterminate TB‐IGRA following SARS‐CoV‐2 infection or vaccination and to review associated factors.
Aicha Ben Tekaya   +6 more
wiley   +1 more source

Design and development of a multi‐epitope vaccine for the prevention of latent tuberculosis infection

open access: yesMedicine Advances, Volume 1, Issue 4, Page 361-382, December 2023., 2023
Abstract Background Latent tuberculosis infection (LTBI) often progresses to active tuberculosis, necessitating the development of novel vaccine to prevent LTBI. In this study, we aimed to design a Mycobacterium tuberculosis (M. tuberculosis) vaccine that could elicit a potent immune response to prevent LTBI.
Fan Jiang   +5 more
wiley   +1 more source

Longitudinal analysis of QuantiFERON-TB Gold In-Tube in children with adult household tuberculosis contact in South Africa: a prospective cohort study. [PDF]

open access: yesPLoS ONE, 2011
QuantiFERON-TB Gold In Tube (QFT-GIT) is a tool for detecting M. tuberculosis infection. However, interpretation and utility of serial QFT-GIT testing of pediatric tuberculosis (TB) contacts is not well understood.
Maunank Shah   +5 more
doaj   +1 more source

Bottlenecks and recent advancements in detecting Mycobacterium tuberculosis in patients with HIV

open access: yesiLABMED, Volume 1, Issue 1, Page 44-57, June 2023., 2023
Tuberculosis (TB) is difficult to diagnose, particulally in HIV‐positive individuals, leading to a delayed disease treatment and poor prognosis. Herein, we summarize the strengths and limitations of current TB diagnostic methods, and shed light on the obstacles of TB diagnosis in people living with HIV.
Zixun Lin   +6 more
wiley   +1 more source

Pulmonary tuberculosis associated acute fibrinous and organizing pneumonia: A case report and literature review

open access: yesThe Clinical Respiratory Journal, Volume 17, Issue 6, Page 499-506, June 2023., 2023
Pulmonary tuberculosis presenting secondary OP and AFOP are rare. We present a case of 44‐year‐old male with AFOP secondary to Mycobacterium tuberculosis and searched existing literature relevant to OP and AFOP caused by tuberculosis. Abstract Background Acute fibrinous and organizing pneumonia (AFOP) is a rare histological interstitial pneumonia ...
Xiang Zhao   +3 more
wiley   +1 more source

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