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Sensitivity and specificity of QuantiFERON-TB Gold Plus compared with QuantiFERON-TB Gold In-Tube and T-SPOT.TB on active tuberculosis in Japan

Journal of Infection and Chemotherapy, 2018
The QuantiFERON-TB Gold Plus (QFT-Plus) was introduced in 2015 as a new generation of interferon-gamma release assays (IGRAs) designed to detect Mycobacterium tuberculosis infection (TB). Examination of its diagnostic accuracy is crucial before it is launched in Japan.We examined 99 patients with laboratory-confirmed active TB (patients) and 117 ...
Jin Takasaki   +8 more
openaire   +2 more sources

IL-1RA in the supernatant of QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus is useful for discriminating active tuberculosis from latent infection

Journal of Infection and Chemotherapy, 2021
The new-generation QuantiFERON (QFT)-TB Gold Plus (QFT-Plus) is expected to be useful because it includes a new peptide that is supposed to induce a CD8+ T cell response. There is a need for a new marker with sensitivity higher than that of the conventional IFN-γ release assays owing to false-negative results in the latter.
Shunsuke Akashi   +15 more
openaire   +2 more sources

Evaluation of treatment response in active tuberculosis using QuantiFERON-TB Gold Plus

European Cytokine Network, 2020
Tuberculosis (TB) is one of the leading infectious causes of death worldwide and despite the progress recently made in TB control at a global level, the decline in its incidence is still slow. It is therefore crucial to evaluate the performance of new tools for monitoring of TB treatment.
Setareh, Mamishi   +4 more
openaire   +2 more sources

Serial testing of Mycobacterium tuberculosis infection in Chinese village doctors by QuantiFERON-TB Gold Plus, QuantiFERON-TB Gold in-Tube and T-SPOT.TB

Journal of Infection, 2019
To evaluate the performance of QuantiFERON-TB Gold Plus (QFT-Plus) on Mycobacterium tuberculosis (MTB) infection test among registered village doctors from China.MTB infection of the registered village doctors in Zhongmu County were tested using QFT-Plus and two other interferon-gamma release assays (IGRAs) in parallel: QuantiFERON-TB Gold In-Tube (QFT)
Haoran, Zhang   +13 more
openaire   +2 more sources

CD8 response measured by QuantiFERON-TB Gold Plus and tuberculosis disease status

Journal of Infection, 2019
Clinical application of the CD8 response as measured by the newer interferon gamma release assay, QuantiFERON-TB Gold-Plus (QFT-Plus), remains to be investigated.We performed this prospective study and recruited active TB patients, contacts with latent tuberculosis infection (LTBI) and contacts without LTBI in two centres in northern Taiwan in 2017 ...
Meng-Rui, Lee   +6 more
openaire   +2 more sources

Method comparison of QIAGEN QuantiFERON-TB gold plus ELISA and LIAISON® QuantiFERON-TB gold plus for latent tuberculosis infection detection in pregnant ugandan women

Diagnostic Microbiology and Infectious Disease
The DiaSorin LIAISON® QuantiFERON-TB Gold Plus test offers automation advantages over the standard QIAGEN ELISA; however, data comparing the two methods in pregnant women are lacking. We assessed the categorical and quantitative agreement between these interferon-gamma release assay platforms for latent tuberculosis infection (LTBI) detection in a ...
Felix Bongomin   +5 more
openaire   +2 more sources

QuantiFERON-TB Gold Plus: can we stop at three?

Pathology, 2023
Yuan Yi Constance Chen, Partha Pratim De
openaire   +1 more source

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