Results 91 to 100 of about 327,904 (307)
Advanced Science, EarlyView.Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu +12 more
wiley +1 more source
Peptide selection for targeted protein quantitation
, 2017 Targeted proteomics methods in their different flavors rely on the use of a few peptides as proxies for protein quantitation, which need to be specified either prior to or after data acquisition.
Sabidó Aguadé, Eduard, 1981- +1 more
core +2 more sources
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
UV SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE DETERMINATION OF AGOMELATINE IN COATED TABLETS
Drug Analytical Research, 2017 UV spectrophotometry is an analytical technique used routinely for qualitative and quantitative assay due the low cost and reliability during analysis.
Fábio de Souza Barbosa +6 more
doaj +1 more source
In Vitro Fluorescent Evalution - Quantitation
, 2016 This file contains all of the raw and analyzed fluorescent quantitation data for assessing localization of conjugates with various cell lines (Fig. 3)
Ramaswamy Kalyanasundaram (327278) +13 more
core +1 more source
Advanced Science, EarlyView.A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong +17 more
wiley +1 more source
Quantitation of constituents in Greek propolis extracts.
, 2017 Quantitation of constituents in Greek propolis extracts.
Pelagia Anastasiadou (3684904) +3 more
core +1 more source
Advanced Science, EarlyView.Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian +10 more
wiley +1 more source
Quantitation of protein variants from milk samples.
, 2016 Quantitation of protein variants from milk samples.
Delphine Vincent (2131087) +4 more
core +1 more source
Advanced Science, EarlyView.GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong +11 more
wiley +1 more source