Results 141 to 150 of about 498,441 (308)

Quantitative PCR [PDF]

open access: yesNature, 1993
R J, Wiesner, B, Beinbrech, J C, Rüegg
openaire   +2 more sources

Digital Surface‐Enhanced Raman Scattering With Event Counting and Spectrum Learning for Label‐Free Protein Quantification

open access: yesAdvanced Intelligent Systems, EarlyView.
A statistical and machine learning‐assisted surface‐enhanced Raman scattering (SERS) framework is developed for label‐free quantification of low‐abundance analytes, including proteins. Combining digital SERS event counting with binomial regression and an artificial neural network (ANN) trained on full spectra, the approach achieves picomolar detection ...
Eni Kume, James Rice
wiley   +1 more source

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

open access: yesAngewandte Chemie, EarlyView.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach   +4 more
wiley   +2 more sources

Utilization and Separation of Flavonoids in the Food and Medicine Industry: Current Status and Perspectives

open access: yesSeparations
Flavonoids are the most abundant functional compounds distributed in higher plants, and are used as important dietary components for human health protection.
Jianan Wang   +4 more
doaj   +1 more source

Characterization and Quantitation of Anthocyanins of the Pigmented Tea Cultivar TRI 2043 (Camellia sinensis L.) from Sri Lanka

open access: yesSeparations
Tea leaves are rich in diverse bioactive compounds. The tea accession TRI 2043 is unique due to its pigmented leaves caused by anthocyanins, clonal origin, resistance to blister blight disease, and high pubescence density. Because of its peculiarity, TRI
Philipp Hopfstock   +5 more
doaj   +1 more source

Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. [PDF]

open access: yes, 2017
Introduction: Fatty acid ethanolamides (FAEs) are a family of lipid mediators that participate in a host of biological functions. Procedures for the quantitative analysis of FAEs include organic solvent extraction from biological matrices (e.g., blood ...
Angelini, Roberto   +3 more
core  

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew   +8 more
wiley   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen   +6 more
wiley   +1 more source

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng   +3 more
wiley   +1 more source

Quantitative Anesthesia

open access: yesVeterinary Clinics of North America: Small Animal Practice, 1992
Quantitative anesthesia is delivering anesthetic and oxygen in known quantities, the dosage based on calculations for their uptake. The uptake is not linearly related to body weight but is linearly related to body weight raised to a power. The dosage of inhaled anesthetics is calculated by the method of Lowe.
openaire   +2 more sources

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