Results 101 to 110 of about 7,493,012 (309)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
The Quantitative Genetic Architecture of the Bold-Shy Continuum in Zebrafish, Danio rerio
PLoS ONE, 2013 In studies of consistent individual differences (personality) along the bold-shy continuum, a pattern of behavioral correlations frequently emerges: individuals towards the bold end of the continuum are more likely to utilize risky habitat, approach ...
Mary E. Oswald, M. Singer, B. Robison
semanticscholar +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Estimation of genetic parameters and identification of selection indices in exotic tomato genotypes [PDF]
Electronic Journal of Plant Breeding, 2014 A study was undertaken to evaluate and characterize seventeen exotic genotypes of tomato grown in eastern India and to identify important selection indices for the yield improvement of the crop.
Pemba Sherpa, N. Pandiarana, Varun Durwas Shende, Tania Seth, Subhra Mukherjee and Arup Chattopadhyay
doaj
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Resistance of Eucalyptus pellita to rust (Puccinia psidii) [PDF]
Crop Breeding and Applied Biotechnology, 2014 Eucalypts rust (Puccinia psidii) is currently one of the major diseases in commercial eucalypt plantations in Brazil. The primary method of disease control is the use of resistant genotypes, and, among the different species of Eucalyptus, E. pellita is
Marisângela Rodrigues Santos +5 more
doaj
Understanding Genetic Diversity of Sorghum Using Quantitative Traits
Scientifica, 2016 Sorghum is the important cereal crop around the world and hence understanding and utilizing the genetic variation in sorghum accessions are essential for improving the crop.
Sweta Sinha, N. Kumaravadivel
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Genetic ResourcesThe genetic diversity of multiple animal species is now declining rapidly, highlighting the need for action to protect and preserve animal genetic resources for the long term.
Ellen-Louisa F. White +10 more
doaj +1 more source
Anatomic brain asymmetry in vervet monkeys. [PDF]
, 2011 Asymmetry is a prominent feature of human brains with important functional consequences. Many asymmetric traits show population bias, but little is known about the genetic and environmental sources contributing to inter-individual variance.
Abaryan, Zvart +9 more
core +1 more source