Results 21 to 30 of about 4,302,850 (309)

Plasma proteomic associations with genetics and health in the UK Biobank

Nature, 2023
The Pharma Proteomics Project generates the largest open-access plasma proteomics dataset to date, offering insights into trans protein quantitative trait loci across multiple biological domains, and highlighting genetic influences on ligand–receptor ...
B. Sun, Joshua Chiou, M. Traylor, C. Benner, Yi-Hsiang Hsu, Tom G Richardson, P. Surendran, A. Mahajan, Chloe Robins, Steven G. Vasquez-Grinnell, Liping Hou, E. Kvikstad, O. Burren, Jonathan Davitte, Kyle L. Ferber, C. Gillies, Åsa K Hedman, Sile Hu, Tinchi Lin, Rajesh Mikkilineni, Rion K. Pendergrass, Corran Pickering, Bram Prins, Denis Baird, Chia-Yen Chen, Lucas D. Ward, A. Deaton, Samantha Welsh, Carissa M. Willis, Nick Lehner, M. Arnold, Maria A. Wörheide, Karsten Suhre, G. Kastenmüller, A. Sethi, M. Cule, Anil Raj, Hyun Ming Kang, L. Burkitt-Gray, E. Melamud, Mary Helen Black, E. Fauman, J. Howson, Hyun Min Kang, M. McCarthy, P. Nioi, S. Petrovski, Robert A. Scott, Erin N. Smith, S. Szalma, D. Waterworth, L. Mitnaul, J. Szustakowski, Brad Gibson, Melissa R. Miller, Christopher D. Whelan   +55 more
semanticscholar   +1 more source

Multivariate Survival Mixed Models for Genetic Analysis of Longevity Traits [PDF]

, 2014
A class of multivariate mixed survival models for continuous and discrete time with a complex covariance structure is introduced in a context of quantitative genetic applications.
Labouriau, Rodrigo, Madsen, Per, Maia, Rafael Pimentel   +2 more
core   +2 more sources

Signal and Noise in Correlation Matrix [PDF]

, 2004
Using random matrix technique we determine an exact relation between the eigenvalue spectrum of the covariance matrix and of its estimator. This relation can be used in practice to compute eigenvalue invariants of the covariance (correlation) matrix ...
A. Görlich, A. Jarosz, Burda, Crisanti, Feinberg, J. Jurkiewicz, Opper, Silverstein, Z. Burda   +8 more
core   +1 more source

Effective Selection for Lower Mortality in Organic Pigs through Selection for Total Number Born and Number of Dead Piglets

Animals, 2022
Selection for the number of living pigs on day 11 (L11) aims to reduce piglet mortality and increase litter size simultaneously. This approach could be sub-optimal, especially for organic pig breeding.
Roos M. Zaalberg, Trine M. Villumsen, Just Jensen, Thinh T. Chu   +3 more
doaj   +1 more source

GENES - a software package for analysis in experimental statistics and quantitative genetics - doi: 10.4025/actasciagron.v35i3.21251

, 2013
GENES is a software package used for data analysis and processing with different biometric models and is essential in genetic studies applied to plant and animal breeding.
C. Cruz
semanticscholar   +1 more source

Selection responses of means and inbreeding depression for female fecundity in Drosophila melanogaster suggest contributions from intermediate-frequency alleles to quantitative trait variation [PDF]

, 2007
The extent to which quantitative trait variability is caused by rare alleles maintained by mutation, versus intermediate-frequency alleles maintained by balancing selection, is an unsolved problem of evolutionary genetics.
Borthwick, Helen, Charlesworth, Brian, Miyo, Takahiro   +2 more
core   +1 more source

Genomic prediction in Nordic Red dairy cattle considering breed origin of alleles

Journal of Dairy Science, 2022
: This study investigated the reliability of genomic prediction (GP) using breed origin of alleles (BOA) approach in the Nordic Red (RDC) population, which has an admixed population structure.
Ana Guillenea, Guosheng Su, Mogens Sand⊘ Lund, Emre Karaman   +3 more
doaj   +1 more source

Dynamical Models in Quantitative Genetics [PDF]

, 1984
In this paper the author investigates models in quantitative genetics and shows that under quite reasonable assumptions the dynamics can display rather counter-intuitive behavior.
A Gimelfarb, B Charlesworth, DS Falconer, E Mayr, I Rechenberg, J Felsenstein, JM Smith, M Kirkpatrick, M Slatkin, M Turelli, N Eldredge, R Bürger, R Lande, R Lande, R Lande, R Lande, R Lande, R Riedl, S Karlin, S Wright, S Wright, SJ Gould, Wagner, Wagner   +23 more
core   +1 more source

Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle

BMC Genomics, 2018
Background Improving resistance to mastitis, one of the costliest diseases in dairy production, has become an important objective in dairy cattle breeding. However, mastitis resistance is influenced by many genes involved in multiple processes, including
Zexi Cai, Bernt Guldbrandtsen, Mogens Sandø Lund, Goutam Sahana   +3 more
doaj   +1 more source

Is evolution predictable? Quantitative genetics under complex genotype-phenotype maps

bioRxiv, 2019
A fundamental aim of post-genomic 21st century biology is to understand the genotype-phenotype map (GPM) or how specific genetic variation relates to specific phenotypic variation (1). Quantitative genetics approximates such maps using linear models, and
Lisandro Milocco, I. Salazar-Ciudad
semanticscholar   +1 more source