Results 81 to 90 of about 3,034,324 (297)

Quantitative analysis of phase wave of gene expression in the mammalian central circadian clock network. [PDF]

PLoS ONE, 2011
BACKGROUND: The suprachiasmatic nucleus (SCN), the master circadian clock, is a heterogeneous oscillator network, yet displays a robust synchronization dynamics.
Hirokazu Fukuda, Isao Tokuda, Seiichi Hashimoto, Naoto Hayasaka   +3 more
doaj   +1 more source

Optimal illumination scheme for isotropic quantitative differential phase contrast microscopy [PDF]

, 2019
Differential phase contrast microscopy (DPC) provides high-resolution quantitative phase distribution of thin transparent samples under multi-axis asymmetric illuminations.
Chen, Qian, Fan, Yao, Pan, Xiangpeng, Sun, Jiasong, Tian, Lei, Zuo, Chao   +5 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Quantitative and Qualitative Analysis of Aircraft Round-Trip Times Using Phase Type Distributions

Mathematics
One of the major issues facing commercial airlines is the time that it takes to board passengers. Further, most airlines wish to increase the number of trips that an aircraft can make between two or more cities.
Srinivas R. Chakravarthy
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Thermodynamic model for predicting mineral phase distribution in cement-stabilized kaolinite

Yantu gongcheng xuebao
In this study, a new method based on a chemical thermodynamic model is proposed to quantitatively predict the phase distribution in cemented soil. Commercial kaolinite with simple phase composition is selected, and a series of cemented kaolinite samples ...
GE Jinyu1, 2 , XU Fei1 , HAN Xun1, HAN Xuesong1, QIAN Wenxun1, LI Huaisen1
doaj   +1 more source

Quantitative analysis of vapor concentration in unsteady evaporating gasoline spray with LIEF method (2nd Report：Analysis of mixture-liquid two-phase characteristics)

Nihon Kikai Gakkai ronbunshu, 2020
This paper reports the quantitative analysis of vapor concentration in the mixture-liquid two-phase region with Laser Induced Exciplex Fluorescence（LIEF）for the unsteady evaporating gasoline type spray.
Dai MATSUDA, Eriko MATSUMURA, Jiro SENDA
doaj   +1 more source

Quantum phase transitions in a two-dimensional quantum XYX model: Ground-state fidelity and entanglement

, 2009
A systematic analysis is performed for quantum phase transitions in a two-dimensional anisotropic spin 1/2 anti-ferromagnetic XYX model in an external magnetic field.
Bo Li, D. Perez-Garcia, Huan-Qiang Zhou, S. Sachdev, Sheng-Hao Li, X.-G. Wen   +5 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source