Results 81 to 90 of about 1,156,255 (309)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Application of headspace solid phase microextraction to qualitative and quantitative analysis of tobacco additives in cigarettes

, 2006
Cigarettes may contain up to 10% by weight additives which are intended to make them more attractive. A fast and rugged method for a cigarette-screening for additives with medium volatility was developed using automatic headspace solid phase ...
Pragst, F., Merckel, Careen, Bernhard, Werner, Pragst, Fritz, Merckel, C., Aebi, B., Sporkert, F., Sporkert, Frank, Ratzinger, A., Aebi, Beat, Bernhard, W., Ratzinger, Astrid   +11 more
core   +1 more source

Rapid Analysis of Feldspar by X-ray Diffractometry Rietveld Refinement Method

Yankuang ceshi, 2017
The content of minerals in feldspar can be calculated by chemical analytical results, but the analytical process is long and the calculation process is complex.
RAN Jing, DU Gu, WANG feng-yu
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Quantitative phase imaging for blood cytometry

, 2010
Blood smear analysis has remained a crucial diagnostic tool for pathologists despite the advent of automatic analyzers such as flow cytometers and impedance counters.
Mir, Mustafa A.
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Phase transformations of aged patina formed on weathering steel bridge girders

Results in Engineering
Weathering steel relies on the formation of a stable patina to resist atmospheric corrosion. While the protective layer performs well under normal exposure conditions, its effectiveness diminishes in environments with elevated moisture or in the presence
Pushkar Shivechchhu, Arash Rockey, Seung Hyun Yoon, Zhen Zhang, Arash Noshadravan, Anna C. Birely, Matthew Yarnold, Stefan Hurlebaus   +7 more
doaj   +1 more source

Quantitative analysis of vapor concentration in unsteady evaporating gasoline spray with LIEF method (2nd Report：Analysis of mixture-liquid two-phase characteristics)

Nihon Kikai Gakkai ronbunshu, 2020
This paper reports the quantitative analysis of vapor concentration in the mixture-liquid two-phase region with Laser Induced Exciplex Fluorescence（LIEF）for the unsteady evaporating gasoline type spray.
Dai MATSUDA, Eriko MATSUMURA, Jiro SENDA
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Quantitative analysis of human umbilical vein endothelial cell morphology and tubulogenesis

Primary human umbilical vein endothelial cells can grow as both a monolayer in culture and also as a capillary-like network making them an ideal model system in order to study vascular remodelling.
Hill, Stephen, Mignone, Viviane, Woolard, Jeanette, Kilpatrick, Laura, Moore, Benjamin, Arruda, Maria, Goulding, Joëlle   +6 more
core   +1 more source