Results 61 to 70 of about 3,034,324 (297)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Quantitative analysis of aqueous phase composition of model dentin adhesives experiencing phase separation [PDF]
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2012 AbstractThere have been reports of the sensitivity of our current dentin adhesives to excess moisture, for example, water‐blisters in adhesives placed on over‐wet surfaces, and phase separation with concomitant limited infiltration of the critical dimethacrylate component into the demineralized dentin matrix. To determine quantitatively the hydrophobic/
Ye, Qiang +7 more
openaire +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Acta Chimica Slovenica, 2017 The effect of limestone on the hydration of Portland cement has been studied by many researchers. However, a possible influence of adding more soluble carbonates was not explained.
Simona Medvešček +2 more
doaj +1 more source
Construction of equilibrium networks with an energy function
, 2007 We construct equilibrium networks by introducing an energy function depending on the degree of each node as well as the product of neighboring degrees.
Bollobás B +5 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Fermi gases with imaginary mass imbalance and the sign problem in Monte Carlo calculations [PDF]
, 2013 Fermi gases in strongly coupled regimes, such as the unitary limit, are inherently challenging for many-body methods. Although much progress has been made with purely analytic methods, quantitative results require ab initio numerical approaches, such as ...
Braun, Jens +3 more
core +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Quantitative Convolutional Neural Network Based Multi-Phase XRD Pattern Analysis
Current Directions in Biomedical EngineeringX-ray diffraction (XRD) is commonly used to analyze phase compositions of crystalline samples. Medical applications include the analysis of biotechnological materials and gall- and kidney stones, where composition can inform pathology assessment.
Höfer Hawo H. +5 more
doaj +1 more source