Results 61 to 70 of about 1,156,255 (309)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Quantitative phase microscopy (QPM) has recently emerged as a powerful label-free technique in the field of living cell imaging allowing to non-invasively measure with a nanometric axial sensitivity cell structure and dynamics.
Rappaz, Benjamin +5 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Multiple solid-phase microextraction in a non equilibrium situation. Application in quantitative analysis of chlorophenols and chloroanisoles related to cork taint in wine [PDF]
, 2005 Multiple HS-solid-phase microextraction (MHS-SPME) is a modification of SPME developed for quantitative analysis that avoids possible matrix effects based on an exhaustive analyte extraction from the sample.
Pizarro, C. [0000-0001-6450-8741] +2 more
core +1 more source
Quantitative Convolutional Neural Network Based Multi-Phase XRD Pattern Analysis
Current Directions in Biomedical EngineeringX-ray diffraction (XRD) is commonly used to analyze phase compositions of crystalline samples. Medical applications include the analysis of biotechnological materials and gall- and kidney stones, where composition can inform pathology assessment.
Höfer Hawo H. +5 more
doaj +1 more source
Application of Deep Learning in the Phase Processing of Digital Holographic Microscopy
PhotonicsDigital holographic microscopy (DHM) provides numerous advantages, such as noninvasive sample analysis, real-time dynamic detection, and three-dimensional (3D) reconstruction, making it a valuable tool in fields such as biomedical research, cell ...
Wenbo Jiang, Lirui Liu, Yun Bu
doaj +1 more source
Applied Sciences, 2018 To understand complex biological processes, scientists must gain insight into the function of individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the cell’s life is retrieved, live-cell imaging allows ...
Zahra El-Schich +2 more
doaj +1 more source
Quantitative Analysis of Vortical Blood Flow in the Thoracic Aorta Using 4D Phase Contrast MRI. [PDF]
PLoS ONE, 2015 Phase contrast MRI allows for the examination of complex hemodynamics in the heart and adjacent great vessels. Vortex flow patterns seem to play an important role in certain vascular pathologies.
Jochen von Spiczak +5 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Quantitative Analysis of Balancing Range for Single-Phase 3L-NPC Converters
EnergiesMultiple techniques have been suggested to achieve control balance in single-phase three-level neutral-point clamped (3L-NPC) converters. Nevertheless, there is a deficiency of quantitative calculations related to the extent of balancing.
Ziying Wang +5 more
doaj +1 more source