Results 51 to 60 of about 1,156,255 (309)

Quantitative Analysis of the Phase Transition Mechanism Underpinning the Systemic Self-Assembly of a Mechanopharmaceutical Device

Pharmaceutics, 2021
Clofazimine (CFZ) is a poorly soluble, weakly basic, small molecule antibiotic clinically used to treat leprosy and is now in clinical trials as a treatment for multidrug resistant tuberculosis and COVID-19.
Steven Dunne, Andrew R. Willmer, Rosemary Swanson, Deepak Almeida, Nicole C. Ammerman, Kathleen A. Stringer, Edmund V. Capparelli, Gus R. Rosania   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Investigation Phase: Quantitative Analysis of Domain Ontology Usage (QUA-AF)

, 2018
© 2018, Springer International Publishing AG, part of Springer Nature. In the previous chapter, the EMP-AF was proposed to perform an empirical analysis of domain ontology usage.
Hussain, FK, Farookh Khadeer Hussain, Elizabeth J. Chang, Ashraf, J, Jamshaid Ashraf, Hussain, OK, Chang, EJ, Omar K. Hussain   +7 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quantitative analysis by HPLC-MS2 of the pyrrolizidine alkaloid adonifoline in Senecio scandens

, 2008
A quantitative method using HPLC-MS2 has been developed for the determination of adonifoline, one of the retronecine-type hepatotoxic pyrrolizidine alkaloids in Senecio scandens Buch.-Ham. ex D. Don., a traditional Chinese herb.
Wang, C.-H., Zhang, F., Ma, H.Y., Wang, W., Zhang, M., Wang, Z., Bligh, S.W.A., Zhang, C.-F., Chen, L.X.   +8 more
core   +1 more source

Quantitative phase analysis in semicrystalline materials using the Rietveld method. [PDF]

, 1998
A new procedure to perform quantitative analysis without any internal standard has been developed within Rietveld analysis. This new approach permits solution of the problem due to the presence of an amorphous phase when its chemical composition or the ...
FAGHERAZZI G., CANTON P., CANTON, Patrizia, RIELLO, Pietro, FAGHERAZZI, Giuliano, RIELLO P.   +5 more
core   +1 more source

Quantitative Phase Analysis of Martian Meteorite Alteration [PDF]

Microscopy and Microanalysis, 2010
Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.
E Vicenzi, M Velbel
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Influence of Various Soluble Carbonates on the Hydration of Portland Cement studied by X-ray Diffraction

Acta Chimica Slovenica, 2017
The effect of limestone on the hydration of Portland cement has been studied by many researchers. However, a possible influence of adding more soluble carbonates was not explained.
Simona Medvešček, Venčeslav Kaučič, Anton Meden   +2 more
doaj   +1 more source