Results 11 to 20 of about 1,790,645 (373)
Quantitative Structure Activity Relationship Models for the Antioxidant Activity of Polysaccharides. [PDF]
PLoS ONE, 2016 In this study, quantitative structure activity relationship (QSAR) models for the antioxidant activity of polysaccharides were developed with 50% effective concentration (EC50) as the dependent variable.
Zhiming Li +3 more
doaj +2 more sources
Frontiers in Microbiology, 2019 Besides their established antioxidant activity, many phenolic compounds may exhibit significant antibacterial activity. Here, the effect of a large dataset of 35 polyphenols on the growth of 6 foodborne pathogenic or food-spoiling bacterial strains ...
Lynda Bouarab-Chibane +8 more
doaj +2 more sources
International Journal of Molecular Sciences, 2021 Nitroaromatic compounds (NACs) are ubiquitous in the environment due to their extensive industrial applications. The recalcitrance of NACs causes their arduous degradation, subsequently bringing about potential threats to human health and environmental ...
Tao Huang +5 more
semanticscholar +1 more source
3D-QSAR-based pharmacophore determination and design of novel DPP-4 inhibitors [PDF]
Scripta Medica, 2022 Background/Aim: Therapy of diabetes mellitus type 2 includes drugs that act as inhibitors of dipeptidyl peptidase 4 (DPP-4) enzyme. Several DPP-4 inhibitors are marketed today and although they have favourable safety profile and tolerability, they show ...
Rogić Sanja, Gagić Žarko
doaj +1 more source
Journal of Medicinal Chemistry, 2021 The diversity of RNA structural elements and their documented role in human diseases make RNA an attractive therapeutic target. However, progress in drug discovery and development has been hindered by challenges in the determination of high-resolution ...
Zhengguo Cai +3 more
semanticscholar +1 more source
QSAR studies for the acute toxicity of nitrobenzenes to the Tetrahymena pyriformis [PDF]
Journal of the Serbian Chemical Society, 2014 Quantitative structure-activity relationship (QSAR) models play a key role in finding the relationship between molecular structures and the toxicity of nitrobenzenes to Tetrahymena pyriformis.
Wang Dan-Dan +3 more
doaj +1 more source
Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure–activity relationship [PDF]
Royal Society Open Science, 2017 Cinnamaldehyde amino acid Schiff base (CAAS) is a new class of safe, bioactive compounds which could be developed as potential antifungal agents for fungal infections.
Hui Wang +6 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2020 Background Prostate cancer is the most common non-cutaneous cancer in males and accounts for about 4% of all cancer-related deaths in males annually.
Fabian A. Ikwu +2 more
doaj +1 more source
Correlation between the lipophilicity and antifungal activity of some benzoxazole derivatives [PDF]
Acta Periodica Technologica, 2010 In the present work, a quantitative relationship between the lipophilicity and antifungal activity of some benzoxazole derivatives against Candida albicans was investigated by using QSAR (quantitative structure-activity relationship) analyses.
Podunavac-Kuzmanović Sanja O. +1 more
doaj +1 more source
مجله دانشکده پزشکی اصفهان, 2020 Background: Due to the growing population of the elderly and the increasing trend of Alzheimer's disease, evaluation of acetylcholinesterase (AChE) and butyl cholinesterase (BChE) inhibitors, as major causes of Alzheimer's disease, is essential.
Fahimeh Motamedi +2 more
doaj +1 more source