Results 31 to 40 of about 18,939 (195)
Pathogens, 2022 Lyssavirus rabies (RABV) is an RNA virus and, therefore, is subject to mutations due to low RNA polymerase replication fidelity, forming a population structure known as a viral quasispecies, which is the core of RNA viruses’ adaptive strategy.
Juliana Amorim Conselheiro +6 more
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The pepper virome: natural co-infection of diverse viruses and their quasispecies
BMC Genomics, 2017 Background The co-infection of diverse viruses in a host plant is common; however, little is known about viral populations and their quasispecies in the host.
Yeonhwa Jo +5 more
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Quasispecies and recombination
Theoretical Population Biology, 2006 Recombination is introduced into Eigen's theory of quasispecies evolution. Comparing numerical simulations of the rate equations in the non-recombining and recombining cases show that recombination has a strong effect on the error threshold and, for a wide range of mutation rates, gives rise to two stable fixed points in the dynamics. This bi-stability
Jacobi, Martin Nilsson, Nordahl, Mats
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Quasispecies Structure and Persistence of RNA Viruses
Emerging Infectious Diseases, 1998 Viral quasispecies are closely related (but nonidentical) mutant and recombinant viral genomes subjected to continuous genetic variation, competition, and selection.
Esteban Domingo +5 more
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Frontiers in Genetics, 2021 A human co-infected with H1N1 and H7N9 subtypes influenza A virus (IAV) causes a complex infectious disease. The identification of molecular-level variations in composition and dynamics of IAV quasispecies will help to understand the pathogenesis and ...
Peng Lin +12 more
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Semiconservative Replication in the Quasispecies Model [PDF]
, 2003 This paper extends Eigen's quasispecies equations to account for the semiconservative nature of DNA replication. We solve the equations in the limit of infinite sequence length for the simplest case of a static, sharply peaked fitness landscape.
Deeds, Eric J. +2 more
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PAQ: Partition Analysis of Quasispecies [PDF]
Bioinformatics, 2001 Abstract Motivation: The complexities of genetic data may not be accurately described by any single analytical tool. Phylogenetic analysis is often used to study the genetic relationship among different sequences. Evolutionary models and assumptions are invoked to reconstruct trees that describe the phylogenetic relationship among ...
P, Baccam +4 more
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Emerging Microbes and Infections, 2021 Few non-invasive models were established for precisely identifying the immune tolerant (IT) phase from chronic hepatitis B (CHB). This study aimed to develop a novel approach that combined next-generation sequencing (NGS) and machine learning algorithms ...
Mingjie Wang +12 more
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Quasispecies theory for finite populations [PDF]
Physical Review E, 2010 13 pages, 8 ...
Park, J.M. +2 more
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PLoS PathogensRNA viruses and viroids exist and evolve as quasispecies due to error-prone replication. Quasispecies consist of a few dominant master sequences alongside numerous variants that contribute to genetic diversity.
Jian Wu +5 more
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