Results 71 to 80 of about 18,939 (195)
Advanced Science, Volume 12, Issue 44, November 27, 2025.High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu +14 more
wiley +1 more source
In-Host Flat-like Quasispecies: Characterization Methods and Clinical Implications
MicroorganismsThe repeated failure to treat patients chronically infected with hepatitis E (HEV) and C (HCV) viruses, despite the absence of resistance-associated substitutions (RAS), particularly in response to prolonged treatments with the mutagenic agents of HEV ...
Josep Gregori +17 more
doaj +1 more source
Ecology and Evolution, 2020 Piscine novirhabdovirus = Viral Hemorrhagic Septicemia Virus (VHSV) first appeared in the Laurentian Great Lakes with large outbreaks from 2005 to 2006, as a new and novel RNA rhabdovirus subgenogroup (IVb) that killed >30 fish species. Interlude periods
Carol A. Stepien, Megan D. Niner
doaj +1 more source
Unveiling of Evolution Pattern for HY12 Enterovirus Quasispecies and Pathogenicity Alteration
Viruses, 2021 Enterovirus, like the majority of RNA viruses, evolves to survive the changeable environments by a variety of strategies. Here, we showed that HY12 virus evolved to alter its characteristics and pathogenicity by employing a non-synonymous mutation ...
Xiaoran Chang +7 more
doaj +1 more source
A dynamical phase transition in a model for evolution with migration
, 2010 Migration between different habitats is ubiquitous among biological populations. In this Letter, we study a simple quasispecies model for evolution in two different habitats, with different fitness landscapes, coupled through one-way migration. Our model
Allen, Rosalind J. +2 more
core +1 more source
Quasispecies evolution in general mean-field landscapes [PDF]
, 2001 I consider a class of fitness landscapes, in which the fitness is a function of a finite number of phenotypic "traits", which are themselves linear functions of the genotype.
Baake E. +9 more
core +1 more source
A quasispecies on a moving oasis [PDF]
Theoretical Population Biology, 2005 A population evolving in an inhomogeneous environment will adapt differently to different regions. We study the conditions under which such a population can maintain adaptations to a particular region when that region is not stationary, but can move. In particular, we study a quasispecies living near a favorable patch ("oasis") in the middle of a large
Desai, Michael M., Nelson, David R.
openaire +4 more sources
Evolutionary games and quasispecies
, 2002 We discuss a population of sequences subject to mutations and frequency-dependent selection, where the fitness of a sequence depends on the composition of the entire population.
Axelrod R. +16 more
core +3 more sources
Update on Hepatitis E Virus Infection 2025: Insights From an International Symposium
Liver International, Volume 45, Issue 11, November 2025.ABSTRACT Background and Aims The second Hepatitis E Symposium was held as an integral part of the International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart in Berlin. The symposium aimed to provide a comprehensive exploration of hepatitis E virus (HEV) research and bring together clinicians, basic scientists, public health ...
Lara Buchardt +11 more
wiley +1 more source
Cooperating H3N2 Influenza Virus Variants Are Not Detectable in Primary Clinical Samples
mSphere, 2018 The high mutation rates of RNA viruses lead to rapid genetic diversification, which can enable cooperative interactions between variants in a viral population.
Katherine S. Xue +3 more
doaj +1 more source