Results 81 to 90 of about 18,939 (195)
Host-Parasite Co-evolution and Optimal Mutation Rates for Semi-conservative Quasispecies
In this paper, we extend a model of host-parasite co-evolution to incorporate the semi-conservative nature of DNA replication for both the host and the parasite.
D. Voet +4 more
core +1 more source
Modeling HIV quasispecies evolutionary dynamics [PDF]
Abstract Background During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and CXCR4 coreceptors (R5 and X4 phenotypes, respectively). The switch in coreceptor usage has been correlated with a faster progression of the disease to the AIDS ...
Luca Sguanci +2 more
openaire +4 more sources
Dynamical Analysis of an HIV Infection Model Including Quiescent Cells and Immune Response
ABSTRACT This research gives a thorough examination of a human immunodeficiency virus (HIV) infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex interaction between the host's immune response and viral infection.
Ibrahim Nali +3 more
wiley +1 more source
Several pathogens use evolvability as a survival strategy against acquired immunity of the host. Despite their high variability in time, some of them exhibit quite low variability within the population at any given time, a somehow paradoxical behavior ...
Davide Fichera +13 more
core +3 more sources
Discovering Complete Quasispecies in Bacterial Genomes [PDF]
Abstract Mobile genetic elements can be found in almost all genomes. Possibly the most common nonautonomous mobile genetic elements in bacteria are repetitive extragenic palindromic doublets forming hairpins (REPINs) that can occur hundreds of times within a genome.
Bertels, Frederic +2 more
openaire +4 more sources
ABSTRACT Due to the continuous genetic evolution of SARS‐CoV‐2, numerous variants have emerged and different whole genome sequencing techniques, necessary for accurate virus typing, have been developed. In this study, we evaluated the performance of PacBio single‐molecule real‐time (SMRT) sequencing for SARS‐CoV‐2 typing.
Pauline Trémeaux +6 more
wiley +1 more source
Yuan Nie,* Xizi Deng,* Yun Lan, Linghua Li, Feng Li, Fengyu Hu Research Institute, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this ...
Nie Y, Deng X, Lan Y, Li L, Li F, Hu F
doaj
Influenza viruses cause a remarkable disease burden and significant morbidity and mortality worldwide, and these impacts vary between seasons. To understand the mechanisms associated with these differences, a comprehensive approach is needed to ...
Bruno Simon +6 more
doaj +1 more source
The 30th anniversary of quasispecies [PDF]
The meeting on ‘Quasispecies: past, present and future’ took place between 17 and 18 November 2008, in Barcelona, Spain, and was organized by J. Gomez, C. Lopez‐Galindez, M.A. Martinez & A. Mas. ![][1] A meeting was held in Barcelona, Spain, in November 2008 to celebrate the 30th anniversary of the publication of the article that described the ...
Domingo, Esteban, Wain-Hobson, Simon
openaire +2 more sources
ABSTRACT RNA viruses often comprise multiple variants that co‐circulate in a host population, with potentially complex dynamics. Deformed wing virus (DWV), arguably the most impactful virus of honey bees (Apis mellifera), nowadays exists as two major variants, genotypes A (DWV‐A) and B (DWV‐B), which provide an amenable window into the dynamics of ...
Fernando A. Fleites‐Ayil +5 more
wiley +1 more source

