Results 71 to 80 of about 1,931 (288)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Trace Invariance for Quaternion Matrices [PDF]
, 2015 Let F be a f ield. It is a classical result in linear algebra that for each A, P ϵ Mn (F) such that P is nonsingular, tr A = tr (PAP-1). We show in this paper that the preceding property does not hold true if F is the division ring of real quaternions ...
de la Cruz, Ralph John
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MONOMIAL (1, 0,-1) MATRIX OF THE FOURTH ORDER, ISOMORPHIC TO THE GROUP OF QUATERNIONS
Nauka ta progres transportu, 2009 A set of direct and inverse elements are examined and compared with a four-dimensional orthonormal basis. The aggregate of even substitutions of fourth power as a product of two transpositions are formed on this finite set.
V. V. Kravets +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Simultaneous diagonalisation of the covariance and complementary covariance matrices in quaternion widely linear signal processing [PDF]
, 2018 Recent developments in quaternion-valued widely linear processing have established that the exploitation of complete second-order statistics requires consideration of both the standard covariance and the three complementary covariance matrices.
Mandic, Danilo P. +13 more
core +2 more sources
International Journal of Mathematics and Mathematical Sciences, 2012 We establish necessary and sufficient conditions for the existence of and the expressions for the general real and complex Hermitian solutions to the classical system of quaternion matrix equations A1X=C1,XB1=C2, and A3XA3*=C3. Moreover, formulas of the
Shao-Wen Yu
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Characteristic roots of quaternion matrices [PDF]
, 1954 In two recent publications [1], [2] it was shown that for matrices of (real) quaternion elements an eigenvalue theory can be developed similar to that for complex numbers.
Taussky, Olga
core