Results 81 to 90 of about 19,971 (282)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A Fast Projected Gradient Algorithm for Quaternion Hermitian Eigenvalue Problems
MathematicsIn this paper, based on the novel generalized Hamilton-real (GHR) calculus, we propose for the first time a quaternion Nesterov accelerated projected gradient algorithm for computing the dominant eigenvalue and eigenvector of quaternion Hermitian ...
Shan-Qi Duan, Qing-Wen Wang
doaj +1 more source
Algebra and geometry of Hamilton's quaternions
, 2016 Inspired by the relation between the algebra of complex numbers and plane geometry, William Rowan Hamilton sought an algebra of triples for application to three dimensional geometry.
Krishnaswami, Govind S. +1 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
MONOMIAL (1, 0,-1) MATRIX OF THE FOURTH ORDER, ISOMORPHIC TO THE GROUP OF QUATERNIONS
Nauka ta progres transportu, 2009 A set of direct and inverse elements are examined and compared with a four-dimensional orthonormal basis. The aggregate of even substitutions of fourth power as a product of two transpositions are formed on this finite set.
V. V. Kravets +2 more
doaj
Summing free unitary random matrices
, 2011 I use quaternion free probability calculus - an extension of free probability to non-Hermitian matrices (which is introduced in a succinct but self-contained way) - to derive in the large-size limit the mean densities of the eigenvalues and singular ...
A. Crisanti +11 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2012 We establish necessary and sufficient conditions for the existence of and the expressions for the general real and complex Hermitian solutions to the classical system of quaternion matrix equations A1X=C1,XB1=C2, and A3XA3*=C3. Moreover, formulas of the
Shao-Wen Yu
doaj +1 more source