Results 231 to 240 of about 22,884 (241)
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Analytical and Bioanalytical Chemistry, 2016
This work demonstrates a novel method for DNA methyltransferase (MTase) activity detection with a quencher-free molecular beacon (MB) probe based on exonuclease (Exo) III-assisted signal amplification. In the presence of Dam MTase and DpnI endonuclease, the elaborately designed hairpin substrate (MB1) was cleaved into two parts (part A and part B). Exo
Haisheng, Liu +5 more
openaire +2 more sources
This work demonstrates a novel method for DNA methyltransferase (MTase) activity detection with a quencher-free molecular beacon (MB) probe based on exonuclease (Exo) III-assisted signal amplification. In the presence of Dam MTase and DpnI endonuclease, the elaborately designed hairpin substrate (MB1) was cleaved into two parts (part A and part B). Exo
Haisheng, Liu +5 more
openaire +2 more sources
Biosensors and Bioelectronics
Fluorescent DNA assays are promising in disease diagnosis, environmental monitoring, and drug screening, encompassing both heterogeneous and homogeneous assay types. Nevertheless, heterogeneous assays suffer from tedious washing steps and slow reaction kinetics, whereas homogenous assays require well-designed fluorophore pairs to modulate signal off/on.
Xiaoman Duan, Biwu Liu
exaly +3 more sources
Fluorescent DNA assays are promising in disease diagnosis, environmental monitoring, and drug screening, encompassing both heterogeneous and homogeneous assay types. Nevertheless, heterogeneous assays suffer from tedious washing steps and slow reaction kinetics, whereas homogenous assays require well-designed fluorophore pairs to modulate signal off/on.
Xiaoman Duan, Biwu Liu
exaly +3 more sources
ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Natarajan Venkatesan +2 more
openaire +1 more source
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Natarajan Venkatesan +2 more
openaire +1 more source
Analytica Chimica Acta, 2019
Telomerase is an important biomarker for cancer diagnosis and a valuable target for cancer therapy. Most of the reported telomerase assays suffer from the repeating thermal cycles, laborious protocols, expensive instruments and the limited sensitivity.
Fei Ma +3 more
openaire +2 more sources
Telomerase is an important biomarker for cancer diagnosis and a valuable target for cancer therapy. Most of the reported telomerase assays suffer from the repeating thermal cycles, laborious protocols, expensive instruments and the limited sensitivity.
Fei Ma +3 more
openaire +2 more sources
ChemBioChem, 2013
AbstractWe have prepared two fluorescent DNA probes—UDBF and UDBT, containing 2‐ethynyldibenzofuran and 2‐ethynyldibenzothiophene moieties, respectively, covalently attached to the base dU—and incorporated them in the central positions of oligodeoxynucleotides (ODNs) so as to develop new types of quencher‐free linear beacon probes and investigate the ...
Jiwon, Lee, Hyun Yi, Cho, Gil Tae, Hwang
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AbstractWe have prepared two fluorescent DNA probes—UDBF and UDBT, containing 2‐ethynyldibenzofuran and 2‐ethynyldibenzothiophene moieties, respectively, covalently attached to the base dU—and incorporated them in the central positions of oligodeoxynucleotides (ODNs) so as to develop new types of quencher‐free linear beacon probes and investigate the ...
Jiwon, Lee, Hyun Yi, Cho, Gil Tae, Hwang
openaire +2 more sources
Analytical Methods
New 2-aminopurine-based quencher-free DNA tweezers is proposed with fluorescence properties well tuned by surrounding bases for structural change.
Fangfang Yang +3 more
openaire +2 more sources
New 2-aminopurine-based quencher-free DNA tweezers is proposed with fluorescence properties well tuned by surrounding bases for structural change.
Fangfang Yang +3 more
openaire +2 more sources
Chemical Communications, 2015
We propose a facile fluorometric system for detection of gene mutations using graphene oxide (GO).
Kyoungmin, Roh +7 more
openaire +2 more sources
We propose a facile fluorometric system for detection of gene mutations using graphene oxide (GO).
Kyoungmin, Roh +7 more
openaire +2 more sources
Quencher-free Oligonucleotide-based Fluorescent Probe for Pb2+Ions
Bulletin of the Korean Chemical Society, 2012Min Su Han
exaly