Results 21 to 30 of about 95,816 (273)

Protective Effect of Quercetin 3-O-Glucuronide against Cisplatin Cytotoxicity in Renal Tubular Cells

open access: yesMolecules, 2022
Quercetin, a flavonoid with promising therapeutic potential, has been shown to protect from cisplatin nephrotoxicity in rats following intraperitoneal injection, but its low bioavailability curtails its prospective clinical utility in oral therapy.
Daniel Muñoz-Reyes   +7 more
doaj   +1 more source

Potential ameliorative effect of dietary quercetin against lead-induced oxidative stress, biochemical changes, and apoptosis in laying Japanese quails

open access: yesEcotoxicology and Environmental Safety, 2022
Lead (Pb) is a widespread environmental pollutant which is a toxic threat to human and animal health. The present study was designed to evaluate the ameliorative role of quercetin in laying quails exposed to Pb. A total of 112 birds were randomly divided
Aslihan Sur Arslan   +5 more
doaj  

Quercetin Suppresses Human Glioblastoma Migration and Invasion via GSK3β/β-catenin/ZEB1 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2022
High invasiveness is a biological and clinical characteristic of glioblastoma and predicts poor prognosis of patients. Quercetin, a natural flavonoid compound, exhibits anticancer activity.
Bo Chen   +26 more
doaj   +1 more source

Optimization of Sequential Microwave-Ultrasound-Assisted Extraction for Maximum Recovery of Quercetin and Total Flavonoids from Red Onion (Allium cepa L.) Skin Wastes [PDF]

open access: yesarXiv, 2021
This study aimed to optimize the extraction conditions in order to maximize the recovery yields of quercetin and total flavonoids from red onion skin wastes using sequential microwave-ultrasound-assisted extraction. Five effective factors on quercetin extraction yield were investigated using response surface methodology.
arxiv  

Adsorption of Quercetin on Brown Rice and Almond Protein Matrices: Effect of Quercetin Concentration

open access: yesFoods, 2022
Plant-based proteins are very often used as carriers of different phenolic compounds. For that purpose, complexation of quercetin with almond and brown rice protein matrices was investigated.
Mirela Kopjar   +4 more
doaj   +1 more source

The flavonoid quercetin reverses pulmonary hypertension in rats. [PDF]

open access: yesPLoS ONE, 2014
Quercetin is a dietary flavonoid which exerts vasodilator, antiplatelet and antiproliferative effects and reduces blood pressure, oxidative status and end-organ damage in humans and animal models of systemic hypertension.
Daniel Morales-Cano   +11 more
doaj   +1 more source

Network Pharmacology, Molecular Docking, and MR Analysis: Targets and Mechanisms of Gegen Qinlian Decoction for Helicobacter pylori [PDF]

open access: yesarXiv, 2023
Objective: The study explored therapeutic targets and mechanisms of Gegen Qinlian Decoction for Helicobacter pylori infection and related gastric cancer using network pharmacology, molecular docking, and Mendelian randomization. Methods: Medicinal components of Gegen Qinlian Decoction were extracted from TCMSP and HERB databases.
arxiv  

Quantum Biochemical Analysis of the TtgR Regulator and Effectors [PDF]

open access: yesarXiv, 2022
The recent expansion of multidrug-resistant (MDR) pathogens poses significant challenges in treating healthcare-associated infections. Although antibacterial resistance occurs by numerous mechanisms, active efflux of the drugs is a critical concern. A single species of efflux pump can produce a simultaneous resistance to several drugs.
arxiv  

Negligible Effect of Quercetin in the Pharmacokinetics of Sulfasalazine in Rats and Beagles: Metabolic Inactivation of the Interaction Potential of Quercetin with BCRP

open access: yesPharmaceutics, 2021
Breast cancer resistance protein (BCRP) mediates pharmacokinetic drug interactions. This study evaluated the potential of quercetin to inhibit and induce BCRP in vitro and in vivo. The inhibition of BCRP was investigated for quercetin and its metabolites
Ju-Hee Oh   +6 more
doaj   +1 more source

Quercetin inhibits LPS-induced macrophage migration by suppressing the iNOS/FAK/paxillin pathway and modulating the cytoskeleton

open access: yesCell Adhesion & Migration, 2019
The natural flavonoid quercetin has antioxidant, anti-inflammatory, and anticancer effects. We investigated the effect of quercetin on lipopolysaccharide (LPS)-induced macrophage migration.
Shuna Cui   +5 more
doaj   +1 more source

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