Results 21 to 30 of about 109,616 (314)

Quercetin Attenuates Cardiac Hypertrophy by Inhibiting Mitochondrial Dysfunction Through SIRT3/PARP-1 Pathway

open access: yesFrontiers in Pharmacology, 2021
Cardiac hypertrophy is an important characteristic in the development of hypertensive heart disease. Mitochondrial dysfunction plays an important role in the pathology of cardiac hypertrophy.
Wen-Jing Chen   +7 more
doaj   +1 more source

Prevention of quercetin precipitation in red wines: a promising enzymatic solution

open access: yesOENO One, 2022
Flavonols are known for causing undesirable deposits in both red and white wines. Among flavonols, quercetin is widely considered the principal factor determining this phenomenon. One of the most accredited hypotheses claims that glycosylated derivatives
Veronica Vendramin   +6 more
doaj   +1 more source

Quercetin and Cancer Chemoprevention [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2011
Several molecules present in the diet, including flavonoids, can inhibit the growth of cancer cells with an ability to act as “chemopreventers”. Their cancer‐preventive effects have been attributed to various mechanisms, including the induction of cell‐cycle arrest and/or apoptosis as well as the antioxidant functions.
GIBELLINI, Lara   +8 more
openaire   +4 more sources

Stability of quercetin in DMEM and cell culture with A549 cells

open access: yeseFood, 2022
Quercetin is evidently unstable in Dulbecco's modified Eagle's medium (DMEM) at 37°C. However, the underlying mechanism of this instability is not clear yet. The stability and new degradation products of quercetin in DMEM at 37°C were investigated via in
Hui Cao   +4 more
doaj   +1 more source

In vitro catabolism of quercetin by human fecal bacteria and the antioxidant capacity of its catabolites

open access: yesFood & Nutrition Research, 2014
Background: Part of quercetin flows into the colon after escaping the absorption of the small intestine and will be degraded by colonic microbiota. The catabolites in the colon partially determine the physiological activity of quercetin.
Xichun Peng   +5 more
doaj   +1 more source

Adsorption of Quercetin on Brown Rice and Almond Protein Matrices: Effect of Quercetin Concentration

open access: yesFoods, 2022
Plant-based proteins are very often used as carriers of different phenolic compounds. For that purpose, complexation of quercetin with almond and brown rice protein matrices was investigated.
Mirela Kopjar   +4 more
doaj   +1 more source

Quercetin represses apolipoprotein B expression by inhibiting the transcriptional activity of C/EBPβ. [PDF]

open access: yesPLoS ONE, 2015
Quercetin is one of the most abundant polyphenolic flavonoids found in fruits and vegetables and has anti-oxidative and anti-obesity effects. Because the small intestine is a major absorptive organ of dietary nutrients, it is likely that highly ...
Makoto Shimizu   +3 more
doaj   +1 more source

Quercetin Suppresses Human Glioblastoma Migration and Invasion via GSK3β/β-catenin/ZEB1 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2022
High invasiveness is a biological and clinical characteristic of glioblastoma and predicts poor prognosis of patients. Quercetin, a natural flavonoid compound, exhibits anticancer activity.
Bo Chen   +26 more
doaj   +1 more source

Negligible Effect of Quercetin in the Pharmacokinetics of Sulfasalazine in Rats and Beagles: Metabolic Inactivation of the Interaction Potential of Quercetin with BCRP

open access: yesPharmaceutics, 2021
Breast cancer resistance protein (BCRP) mediates pharmacokinetic drug interactions. This study evaluated the potential of quercetin to inhibit and induce BCRP in vitro and in vivo. The inhibition of BCRP was investigated for quercetin and its metabolites
Ju-Hee Oh   +6 more
doaj   +1 more source

The flavonoid quercetin reverses pulmonary hypertension in rats. [PDF]

open access: yesPLoS ONE, 2014
Quercetin is a dietary flavonoid which exerts vasodilator, antiplatelet and antiproliferative effects and reduces blood pressure, oxidative status and end-organ damage in humans and animal models of systemic hypertension.
Daniel Morales-Cano   +11 more
doaj   +1 more source

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