Results 61 to 70 of about 1,249,380 (278)
Advanced Science, EarlyView.In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
Chirality‐Driven Piezocatalysis in MOFs: Achieving Efficient Cocatalyst‐Free Hydrogen Evolution
Angewandte Chemie, EarlyView.We report a chirality‐driven post‐synthetic modification strategy that grafts chiral L‐histidine (L‐His) onto the Hf6 clusters of MOF‐808(Hf), which significantly boosts the piezoelectricity and charge transfer efficiency, thus significantly enhancing the piezocatalytic performance of MOF‐808(Hf).
Yali Ma +7 more
wiley +2 more sources
Modulation of Cosmic-Ray Antiprotons in the Heliosphere: Simulations for a Solar Cycle
The Astrophysical Journal, 2023 The precision measurements of galactic cosmic-ray protons from the Payload for Antimatter Matter Exploration and Light-nuclei Astrophysics and the Alpha Magnetic Spectrometer are reproduced using a well-established three-dimensional numerical model for ...
O. P. M. Aslam +3 more
doaj +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
Advanced Science, EarlyView.TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen +3 more
wiley +2 more sources
EXCITATION OF ACOUSTIC WAVES BY VORTICES IN THE QUIET SUN [PDF]
The Astrophysical Journal, 2011 10 pages, 5 figure, submitted to ...
Kitiashvili, I. N. +3 more
openaire +2 more sources
Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing
Advanced Science, EarlyView.An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang +10 more
wiley +1 more source
Center-to-limb variations of solar active regions
Astronomy & AstrophysicsAccurate modeling of stellar active regions (ARs) remains a major bottleneck for radial-velocity and transmission-spectroscopy studies aimed at finding Earth-like planets. While much effort has been devoted to AR modeling, their center-to-limb variations
Pietrow A. G. M. +5 more
doaj +1 more source
SELF-CANCELLATION OF EPHEMERAL REGIONS IN THE QUIET SUN [PDF]
The Astrophysical Journal, 2012 6 pages, 4 figures, accepted for publication in ...
Yang, Shuhong +3 more
openaire +2 more sources
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
Advanced Science, EarlyView.This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source