Results 91 to 100 of about 24,434,811 (177)
Aim: A novel series of ethyl 5-(4-substituted phenyl)-3-methyl-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b] quinazoline-2-carboxylate 3a-3j, were synthesized, characterized by spectral, elemental analyses and screened for their in vitro antibacterial and ...
Theivendren Panneer Selvam +2 more
doaj +1 more source
Double lithiation of 2-alkyl-3H-quinazoline-4-thiones, at nitrogen and at the a-hydrogen of the 2-alkyl group (Me, Et, nPr), has been achieved with n-butyllithium at -78 0C in anhydrous THF under nitrogen.
El-Hiti, Gamal A.
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The combination of different «pharmacophore» components in one structure connected via «linker» functional groups is one of the major and justified approaches for the synthesis of new biologically active substances.
Yu. V. Martynenko +3 more
doaj +1 more source
Chemical constituents and ACE inhibitory activity of desert plant Suaeda physophora Pall.
Suaeda physophora Pall. is a kind of desert plant mostly growing in saline habitats in Xinjiang Uygur Autonomous Region. In order to have a better utilization of halophytes, a screening for ACE inhibitors from halophytes growing in Xinjiang was carried ...
Ruizhi Men +8 more
doaj +1 more source
An efficient synthesis of 4-phenoxy-quinazoline, 2-phenoxy-quinoxaline, and 2-phenoxy-pyridine derivatives using aryne chemistry. [PDF]
Zilla MK +5 more
europepmc +1 more source
Quinazoline derivatives as anticancer drugs: a patent review (2011-present)
International audienceIntroduction: Quinazoline is one of the most studied moieties in medicinal chemistry due to the wide range of biological properties such as the anticancer, antibacterial, anti-inflammatory, antimalarial and antihypertensive ...
Ravez, Severine +3 more
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Novel quinazoline derivatives with biological activity
Faculty of Pharmacy in Hradec Králové, Charles University Department of Organic and Bioorganic Chemistry Candidate: Mgr. Zuzana Rania Brožová Supervisor: prof. RNDr. Milan Pour, Ph.D.
Brožová, Zuzana Rania
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Crystal structure and Hirshfeld surface analysis of 3-methyl-4-oxo-N-phenyl-3,4-di-hydro-quinazoline-2-carbo-thio-amide. [PDF]
Pirnazarova N +5 more
europepmc +1 more source
Synthesis and Antioxidant Properties of Novel Quinazoline Derivatives
Quinazoline derivatives have expressed a broad spectrum of biological activities, but there are few examples in literature on an antioxidant activity of different quinazolines. On the basis of literature by Chinese scientists on the effective antioxidant
Tetere, Zenta +4 more
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Antileishmanial activity of a series of
: A series of N-2,N-4-disubstituted quinazoline-2,4-diamines has been synthesized and tested against Leishmania donovani and L. amazonensis intracellular amastigotes.
Dujardin, Jean-Claude +4 more
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