Results 91 to 100 of about 24,434,811 (177)

Design and synthesis of quinazoline carboxylates against Gram-positive, Gram-negative, fungal pathogenic strains, and Mycobacterium tuberculosis

open access: yesJournal of Pharmacy and Bioallied Sciences, 2014
Aim: A novel series of ethyl 5-(4-substituted phenyl)-3-methyl-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b] quinazoline-2-carboxylate 3a-3j, were synthesized, characterized by spectral, elemental analyses and screened for their in vitro antibacterial and ...
Theivendren Panneer Selvam   +2 more
doaj   +1 more source

A simple procedure for the side-chain lithiation of 2-alkyl-3H-quinazoline-4-thiones: application in synthesis

open access: yes, 2004
Double lithiation of 2-alkyl-3H-quinazoline-4-thiones, at nitrogen and at the a-hydrogen of the 2-alkyl group (Me, Et, nPr), has been achieved with n-butyllithium at -78 0C in anhydrous THF under nitrogen.
El-Hiti, Gamal A.
core   +1 more source

2-([1,2,4]triazolo[1,5-c]quinazolin-2-yl-)alkyl-(alkaryl-, aryl-)-amines and their derivatives. (3Н-quinazolin-4-yliden)hydrazides (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)alkyl-(alkaryl-, aryl-)carboxylic acids: features of synthesis, modification and ant

open access: yesZaporožskij Medicinskij Žurnal, 2016
The combination of different «pharmacophore» components in one structure connected via «linker» functional groups is one of the major and justified approaches for the synthesis of new biologically active substances.
Yu. V. Martynenko   +3 more
doaj   +1 more source

Chemical constituents and ACE inhibitory activity of desert plant Suaeda physophora Pall.

open access: yesActa Pharmaceutica Sinica B, 2013
Suaeda physophora Pall. is a kind of desert plant mostly growing in saline habitats in Xinjiang Uygur Autonomous Region. In order to have a better utilization of halophytes, a screening for ACE inhibitors from halophytes growing in Xinjiang was carried ...
Ruizhi Men   +8 more
doaj   +1 more source

Quinazoline derivatives as anticancer drugs: a patent review (2011-present)

open access: yes, 2015
International audienceIntroduction: Quinazoline is one of the most studied moieties in medicinal chemistry due to the wide range of biological properties such as the anticancer, antibacterial, anti-inflammatory, antimalarial and antihypertensive ...
Ravez, Severine   +3 more
core   +1 more source

Novel quinazoline derivatives with biological activity

open access: yes, 2023
Faculty of Pharmacy in Hradec Králové, Charles University Department of Organic and Bioorganic Chemistry Candidate: Mgr. Zuzana Rania Brožová Supervisor: prof. RNDr. Milan Pour, Ph.D.
Brožová, Zuzana Rania
core  

Crystal structure and Hirshfeld surface analysis of 3-methyl-4-oxo-N-phenyl-3,4-di-hydro-quinazoline-2-carbo-thio-amide. [PDF]

open access: yesActa Crystallogr E Crystallogr Commun, 2022
Pirnazarova N   +5 more
europepmc   +1 more source

Synthesis and Antioxidant Properties of Novel Quinazoline Derivatives

open access: yes, 2014
Quinazoline derivatives have expressed a broad spectrum of biological activities, but there are few examples in literature on an antioxidant activity of different quinazolines. On the basis of literature by Chinese scientists on the effective antioxidant
Tetere, Zenta   +4 more
core   +1 more source

Antileishmanial activity of a series of N^{2},N^{4}$-disubstituted quinazoline-2,4-diamines

open access: yes, 2014
: A series of N-2,N-4-disubstituted quinazoline-2,4-diamines has been synthesized and tested against Leishmania donovani and L. amazonensis intracellular amastigotes.
Dujardin, Jean-Claude   +4 more
core  

Home - About - Disclaimer - Privacy