Results 1 to 10 of about 31,065 (253)

Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options [PDF]

open access: yesIndian Pacing and Electrophysiology Journal, 2005
Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in
Maury P, Hocini M, Haïssaguerre M
doaj   +3 more sources

Rational quinidine dosage regimen for atrial fibrillation in Thoroughbred racehorses based on population pharmacokinetics [PDF]

open access: yesFrontiers in Veterinary Science
IntroductionQuinidine (QND) sulfate is an effective treatment for atrial fibrillation (AF) in horses, and several dosage regimens have been proposed to address its wide variability in response and potential adverse effects.
Taisuke Kuroda   +12 more
doaj   +2 more sources

Comparison between Inhibition of CatSper and KSper Channels with NNC 55-0396 and Quinidine on Human Sperm Function [PDF]

open access: yesIranian Journal of Medical Sciences
Background: Calcium enters human sperm through the “Cation Channel of Sperm” (CatSper), while potassium ions exit via the sperm potassium channel (KSper).
Ali Asghar Zarei   +4 more
doaj   +2 more sources

Exploring the Role of the KCNK1 Potassium Channel and Its Inhibition Using Quinidine in Treating Head and Neck Squamous Cell Carcinoma [PDF]

open access: yesClinical and Experimental Otorhinolaryngology
Objectives. Our study aimed to explore the role of the potassium channel KCNK1 in head and neck squamous cell carcinoma, focusing on its impact on tumor growth, invasion, and metastasis.
Hyun Woo Baek, Eunjung Han, Kyoung Ho Oh
doaj   +2 more sources

Quinidine for Brugada syndrome: Panacea or poison? [PDF]

open access: yesHeartRhythm Case Reports, 2016
published_or_final_versio
Jo-Jo Hai, MBBS   +5 more
doaj   +2 more sources

Efficacy of Anti-seizure Medications, Quinidine, and Ketogenic Diet Therapy for KCNT1-Related Epilepsy and Genotype-Efficacy Correlation Analysis

open access: yesFrontiers in Neurology, 2022
AimTo evaluate the efficacy of anti-seizure medications (ASMs), quinidine, and ketogenic diet therapy (KDT) for KCNT1-related epilepsy and to explore genotype-efficacy correlations.MethodsWe collected the data for KCNT1-related epilepsy cases from our ...
Zehong Lin   +30 more
doaj   +1 more source

A case report of pitfall of fever and altered mental status: cerebral malaria due to in an adult traveler returning from Congo [PDF]

open access: yesJournal of Neurocritical Care, 2023
Background Cerebral malaria, caused by Plasmodium falciparum, can lead to severe neurological complications. It is more frequently observed in children than in adults.
Soo-Hyun Park   +4 more
doaj   +1 more source

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]

open access: yes, 2002
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Bromley, Elizabeth V   +5 more
core   +4 more sources

Cardiocerebral channelopathy caused by KCND3 mutation in a child: A case report

open access: yesFrontiers in Pediatrics, 2022
Early repolarization syndrome is rare in children. Mutation of genes encoding ion channels could display mixed electrophysiological phenotype of Kv4.3 including both cardiac phenotype (early repolarization syndrome, atrial fibrillation) and cerebral ...
Yi Zhang, He Jiang, Xiao-mei Li
doaj   +1 more source

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