Results 21 to 30 of about 16,625 (226)

QUINIDINE-CYCLODEXTRINS INCLUSION COMPLEXES [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1999
The complexation behavior of quinidine with four cyclodextrins (CDs)​, namely β-​cyclodextrin (β-​CD)​, hydroxypropyl-​β-​cyclodextrin (HP-​β-​CD)​, methyl-​β-​cyclodextrin (M-​β-​CD) and α-​cyclodextrin (α-​CD) was investigated for the purpose of ...
I. El-Gibaly   +3 more
doaj   +1 more source

Intramolecular Hydrogen Bonds in Conformers of Quinine and Quinidine: An HF, MP2 and DFT Study

open access: yesMolecules, 2017
Quinine is an alkaloid with powerful antimalarial activity, isolated from the bark of Peru’s cinchona trees. Quinidine is an erythro diastereoisomer of quinine also exhibiting antimalarial activity.
Mireille K. Bilonda, Liliana Mammino
doaj   +1 more source

Involvement of Multidrug Resistance Modulators in the Regulation of the Mitochondrial Permeability Transition Pore

open access: yesMembranes, 2022
The permeability transition pore in mitochondria (MPTP) and the ATP-binding cassette transporters (АВС transporters) in cell membranes provide the efflux of low-molecular compounds across mitochondrial and cell membranes, respectively.
Tatiana Fedotcheva   +2 more
doaj   +1 more source

Two South Indian children with KCNT1-related malignant migrating focal seizures of infancy – Clinical characteristics and outcome of targeted treatment with quinidine

open access: yesAnnals of Indian Academy of Neurology, 2019
KCNT1 gene encodes a sodium-gated potassium channel subunit that plays an important role in regulating excitability in neurons. Quinidine is a partial antagonist of this channel.
Abhijit Anil Patil   +2 more
doaj   +1 more source

Electrical storm in an acquired short QT syndrome successfully treated with quinidine

open access: yesClinical Case Reports, 2019
Short QT syndrome (SQTS) is a malignant heart disorder defined by the presence of ventricular arrhythmias causing syncope and sudden cardiac arrest. The prevalence in the pediatric population is 0.05%.
Michael Spartalis   +3 more
doaj   +1 more source

Therapeutic Drug Monitoring of Quinidine in Pediatric Patients with KCNT1 Genetic Variants

open access: yesPharmaceutics, 2022
Quinidine (QND) is an old antimalarial drug that was used in the early 20th century as an antiarrhythmic agent. Currently, QND is receiving attention for its use in epilepsy of infancy with migrating focal seizures (EIMFS) due to potassium sodium ...
Alessandro Ferretti   +7 more
doaj   +1 more source

Systemic lupus erythematosus (SLE) induced by quinidine [PDF]

open access: yes, 1985
Only two definite cases of quinidine-induced systemic lupus erythematosus (SLE) are reported in the English-language literature. We have treated five patients who had an SLE-like syndrome while receiving quinidine.
Carl J. Lavie   +4 more
core   +1 more source

Concurrent Quinidine and Phenobarbital in the Treatment of a Patient with 2 KCNT1 Mutations

open access: yesCurrent Therapeutic Research, 2019
: Epilepsy of infancy with migrating focal seizures is a devastating pediatric neurologic disorder that often results in treatment-resistant seizure activity and developmental delay. The condition has been associated with mutations in the KCNT1 gene that
Camerin C. Passey, PharmD, MBA   +4 more
doaj   +1 more source

Evaluation of propranolol and quinidine in the treatment of quinidine-resistant arrhythmias [PDF]

open access: yes, 1971
Combining propranolol and quinidine should improve the antiarrhythmic action of quinidine by blocking beta adrenergic receptors, an action helpful in cases of arrhythmias associated with anesthetic agents, digitalis and stress.
Reynolds, Jr. , Ernest W.   +2 more
core   +1 more source

Pharmacological analysis of the feeding response of codling moth (Cydia pomonella; Lepidoptera: Tortricidae) neonates to bitter compounds

open access: yesEuropean Journal of Entomology, 2017
Feeding in codling moth neonate caterpillars was inhibited by 0.67 mM and 2.24 mM concentrations of denatonium benzoate. This inhibitory effect was abolished by phospholipase C inhibitor, U-73122 and the phosphodiesterase inhibitor, Rolipram. Quinine and
Maciej A. PSZCZOLKOWSKI
doaj   +1 more source

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