Results 1 to 10 of about 129,805 (284)
Mefloquine resistant malaria in cameroon and correlation with resistance quinine [PDF]
Based on the results of in vitro sensitivity of Plasmodium falciparum to chloroquine, quinine and mefloquine, and evaluation of drug consumption conducted in 1987-1988 in four areas in the noth and south-west of Cameron, two opposite situations were ...
P. Brasseur +3 more
doaj +2 more sources
Synthesis and Biological Activity of Novel Polyazaheterocyclic Derivatives of Quinine [PDF]
A synthetic methodology of the CuAAC “click” approach was exploited for the construction of 1,2-azolyltriazole quinine derivatives by the reaction of O-propargylquinine with azidomethyl-1,2-azoles in methanol.
Gulim K. Mukusheva +10 more
doaj +2 more sources
Background: Malaria is one of the most common infectious and fatal diseases worldwide. Quinine sulfate is one of the antimalarial drug used to treat chloroquine resistant malaria and malaria falciparum.
Soubhagya Ranjan Nayak +2 more
doaj +3 more sources
Quinine blocks 5-HT and 5-HT3 receptor mediated peristalsis in both guinea pig and mouse ileum tissue [PDF]
Introduction. Quinine is commonly used to treat malaria; however one of the principal side effects is gastrointestinal disturbances (White, 1992). 5-HT3 receptors modulate gut peristalsis (Chetty et al., 2006), and, as quinine has been shown to act as a ...
Barrett, Iain D. +4 more
core +2 more sources
Don't You Know That I'm Toxic? Wild Birds Learn to Avoid a Novel Aposematic Warning Signal [PDF]
Many prey species defend themselves against predators by sequestering toxins, which they advertise using conspicuous warning signals—a survival strategy termed ‘aposematism’.
Samuel G. Thompson, Steven J. Portugal
doaj +2 more sources
Bitter taste stimuli induce differential neural codes in mouse brain. [PDF]
A growing literature suggests taste stimuli commonly classified as "bitter" induce heterogeneous neural and perceptual responses. Here, the central processing of bitter stimuli was studied in mice with genetically controlled bitter taste profiles.
Boughter, John D +2 more
core +14 more sources
: Histomoniasis, also commonly referred to as blackhead disease, is caused by the protozoan parasite Histomonas meleagridis. Since the removal of nitarsone in 2015, no approved prophylactics are available for mitigating histomoniasis.
L.C. Beer, B.M. Hargis, C.N. Vuong
doaj +1 more source
Aptamer-based nanotrains and nanoflowers as quinine delivery systems
In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotrains
Mengyuan Cao +10 more
doaj +1 more source
The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Bromley, Elizabeth V +5 more
core +4 more sources
Aversion to Quinine is Associated with Taste Sensation in Chicks
Quinine is known as a bitter compound for humans and also used in animal experiment. However, there is no evidence that animals share the same taste sensation of quinine with humans.
Hiroshi Ueda, Saori Kainou
doaj +1 more source

