Results 41 to 50 of about 129,805 (284)
Malaria Journal, 2012 Background Artemisinin-based combinations are recommended for treatment of uncomplicated falciparum malaria, but are costly and in limited supply. Clindamycin plus quinine is an alternative non-artemisinin-based combination recommended by World Health ...
Obonyo Charles O, Juma Elizabeth A
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PLoS Medicine, 2017 Background Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester except in lifesaving circumstances.
Stephanie Dellicour +25 more
semanticscholar +1 more source
Behavioral Responses of Chicks to a Saccharin-Quinine Mixture
The Journal of Poultry Science, 2018 To date, few reports have been published on the sensitivity of birds to sweet tastes. Therefore, in this study, the behavioral responses of White Leghorn chicks to the sweet taste of saccharin and the bitter taste of quinine were assessed.
Tatsuyuki Yoshida +2 more
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Quinine Sulphate Microparticles as Treatment for Leishmaniasis
Journal of Tropical Medicine, 2020 Background. Leishmaniasis is a neglected tropical disease caused by the Leishmania parasite and transmitted by the female phlebotomine sandfly. The disease can affect the skin (least fatal) or internal organs (most fatal).
Grace Lovia Allotey-Babington +4 more
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Missionaries and the Politics of Quinine in the Gold Coast (1939-1943) [PDF]
Journal of Research on History of Medicine, 2022 While there exists a rich history on anti-malarial drugs and quinine, in particular, the attention of scholars has not reflected the nexuses between the Second World War, quinine shortage and missionaries in the Gold Coast.
Benjamin Darkwa
doaj
The Neural Encoding of Cocaine-Induced Devaluation in The Ventral Pallidum [PDF]
, 2016 Cocaine experience affects motivation structures such as the nucleus accumbens (NAc) and its major output target, the ventral pallidum (VP). Previous studies demonstrated that both NAc activity and hedonic responses change reliably as a taste cue comes ...
Chan, Chung-Lung +2 more
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Angewandte Chemie, 2018 We report a novel approach to the classical natural product quinine that is based on two stereoselective key steps, namely a C−H activation and an aldol reaction, to unite the two heterocyclic moieties of the target molecule.
Daniel H. O’ Donovan +8 more
semanticscholar +1 more source
Talanta Open, 2021 In recent decades, more than 15% of the antimalarials marketed in low- and middle-income countries have been of poor quality, in which quinoline derivatives and quinine-based formulations account for 21%.Near infrared spectroscopy (NIR) was chosen for ...
P.H. Ciza +9 more
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Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh. [PDF]
, 2004 OBJECTIVE: To assess the efficacy of antimalarial treatment and molecular markers of Plasmodium falciparum resistance in the Chittagong Hill Tracts of Bangladesh. METHODS: A total of 203 patients infected with P.
Anderson, T C +6 more
core +2 more sources
A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum. [PDF]
PLoS Genetics, 2014 The emerging resistance to quinine jeopardizes the efficacy of a drug that has been used in the treatment of malaria for several centuries. To identify factors contributing to differential quinine responses in the human malaria parasite Plasmodium ...
Cecilia P Sanchez +8 more
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