Results 51 to 60 of about 107,358 (282)

Quinine blocks 5-HT and 5-HT3 receptor mediated peristalsis in both guinea pig and mouse ileum tissue [PDF]

, 2011
Introduction. Quinine is commonly used to treat malaria; however one of the principal side effects is gastrointestinal disturbances (White, 1992). 5-HT3 receptors modulate gut peristalsis (Chetty et al., 2006), and, as quinine has been shown to act as a ...
Barrett, Iain D., Kelley, Stephen P., Lummis, Sarah, Thompson, Andrew J., Walsh, Jacqueline   +4 more
core  

Microlasers Made Entirely from Edible Substances

Advanced Optical Materials, EarlyView.
Several types of microlasers made completely out of edible substances are developed. They can be embedded directly into edible products and enable the sensing of various parameters, including sugar concentration, pH, the presence of bacteria, and exposure to too‐high temperatures.
Abdur Rehman Anwar, Maruša Mur, Georgia Michailidou, Dimitrios N. Bikiaris, Matjaž Humar   +4 more
wiley   +1 more source

Aptamer-based nanotrains and nanoflowers as quinine delivery systems

International Journal of Pharmaceutics: X, 2023
In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotrains
Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne   +10 more
doaj  

A complex relationship among chemical concentration, detection threshold and suprathreshold intensity of bitter compounds

, 2007
Detection thresholds and psychophysical curves were established for caffeine, quinine-HCl (QHCl), and propylthiouracil (PROP) in a sample of 33 subjects (28 female mean age 24 ± 4).
Adler, Bachmanov, Bartoshuk, BARTOSHUK, Bufe, Caicedo, Chandrashekar, Duffy, Frank, Galindo-Cuspinera, Green, Green, Huang, J. Roper, Jones, Katz, Keast, Keast, Kinnamon, Lawless, McLaughlin, Mojet, Mueller, Ottinger, Peri, P  rez, R. S. J. Keast, Rosenzweig, R  ssler, Small, Yokomukai   +30 more
core   +1 more source

Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]

, 2012
In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Amos, Ben, Chotivanich, Kesinee, Day, Nicholas P J, Dondorp, Arjen M, Fanello, Caterina I, Gesase, Samwel, Gomes, Ermelinda, Hendriksen, Ilse C E, Joseph, Sarah, Karema, Corine, Lee, Sue J, Maitland, Kathryn, Mtove, George, Mwanga-Amumpaire, Juliet, Olaosebikan, Rasaq, Pan-Ngum, Wirichada, Reyburn, Hugh, Saiwaew, Somporn, Silamut, Kamolrat, Tshefu, Antoinette K, von Seidlein, Lorenz, White, Lisa J, White, Nicholas J, Woodrow, Charles   +23 more
core   +5 more sources

High‐Efficiency Blue‐Emitting Multi‐Resonance TADF Organic Light‐Emitting Diodes Constructed on Spiro Quinolinoacridine/Fluorene‐diphenylphosphine Oxide Positional Isomers

Advanced Optical Materials, EarlyView.
We report spiro‐configured hosts constructed on the assembly of a quinolinoacrdine unit and different fluorene positional isomers for high‐performance blue MR‐TADF Organic Light‐Emitting Diodess. The v‐DABNA:CN‐Ir emissive layer combination with SQA‐4‐FPOPh2 as host shows a narrowband emission peak and a high maximum external quantum efficiency of 22.9%
Kelvine Letellier, Yue‐Jian Yang, Wei Gao, Dong‐Ying Zhou, Denis Ari, Cassandre Quinton, Zuo‐Quan Jiang, Cyril Poriel   +7 more
wiley   +1 more source

Drug-induced immune thrombocytopenia: Mapping of the drug binding site to the membrane-proximal region of platelet GPIX

Platelets, 2019
Drug-induced Immune thrombocytopenia (DIT) is a common complication of several medications, including commonly used antibiotics. The most widely studied DIT is caused by quinine. In DIT, antibodies predominantly bind to the platelet membrane glycoprotein
Zohra Ahmadi, Jose Perdomo, Rose Wong, Beng H Chong   +3 more
doaj   +1 more source

ADULTERATION OF QUININE. [PDF]

The Lancet
n ...
openaire   +3 more sources

LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux [PDF]

, 2017
HIGHLIGHTS \u2022 Monovalent cation homeostasis is dysregulated upon LETM1 depletion \u2022 K+/H+ exchange activity is decreased in LETM1 knockdown cells \u2022 LETM1 depletion results in K+ accumulation in the mitochondrial matrix \u2022 LETM1 knockdown
Andrea Mattarei, Christina Pfeiffer, Diego De Stefani, Julia Seifert, Karin Nowikovsky, Mario Zoratti, Mario Zoratti, Mojtaba Tavakoli, Shane Austin   +8 more
core   +2 more sources

Self‐Administered Taste Testing Without Water: Normative Data for the 53‐Item Waterless Empirical Taste Test (WETT)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background According to the National Health and Nutrition Examination Survey (NHANES), more than 20 million Americans suffer from chronic taste problems. Unfortunately, quantitative testing is rarely performed, self‐reports are inaccurate, and “taste” is often confused with olfaction‐dependent flavors.
Richard L. Doty, Ryan Sharetts, Shima T. Moein   +2 more
wiley   +1 more source