Results 301 to 310 of about 140,903 (359)

Computational targeting of allosteric site of MEK1 by quinoline‐based molecules

Cell Biochemistry and Function, 2022
MEK1 is an attractive target due to its role in selective extracellular‐signal‐regulated kinase phosphorylation, which plays a pivotal role in regulating cell proliferation.
Rahul Singh, Vijay Kumar Bhardwaj, Rituraj Purohit   +2 more
semanticscholar   +1 more source

Emerging quinoline‐ and quinolone‐based antibiotics in the light of epidemics

Chemical Biology and Drug Design, 2022
Pandemics are large‐scale outbreaks of infectious disease that can greatly increase morbidity and mortality all the globe. Since past 1990 till twentieth century, these infectious diseases have been major threat all over the globe associated with poor ...
Paranjeet Kaur, Anuradha, Avik Chandra, Tamanna Tanwar, S. Sahu, A. Mittal   +5 more
semanticscholar   +1 more source

Quinoline: Synthesis to Application.

Medicinal chemistry, 2022
This review aims to give a comprehensive report of the quinoline ring, related to its synthesis, reactivity, and therapeutic values. The reactivity of quinoline for the metal, electrophile, and other reactive counterparts defines the shape of the ...
R. Mittal, Meenu Aggarwal, Kavita Khatana, P. Purohit   +3 more
semanticscholar   +1 more source

The contemporary synthetic recipes to access versatile quinoline heterocycles

, 2021
The synthesis of quinoline (C9H7N) and its derivatives attracted the attention of various research communities due to their prominent roles in medicinal chemistry, coordination chemistry and material chemistry.
Basavarajaiah Suliphuldevara Matada, N. Yernale   +1 more
semanticscholar   +1 more source

Quinoline: an attractive scaffold in drug design.

Mini-Reviews in Medical Chemistry, 2021
Quinoline and its derivatives comprise an important group of heterocyclic compounds that exhibits a wide range of pharmacological properties such as antibacterial, antiviral, anticancer, antiparasitic, anti-Alzheimer and anticholesterol.
L. F. E. Moor, T. Vasconcelos, Raisa da R Reis, L. Pinto, Thamires M da Costa   +4 more
semanticscholar   +1 more source

Quinolines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
R. D. Larsen, D. Cai
openaire   +1 more source

Quinoline Derivatives in Discovery and Development of Pesticides.

Journal of Agricultural and Food Chemistry
Finding highly active molecular scaffold structures is always the key research content of new pesticide discovery. In the research and development of new pesticides, the discovery of new agricultural molecular scaffold structures and new targets still ...
Qingfeng Cai, Hongyi Song, Yong Zhang, Zongnan Zhu, Jian Zhang, Jixiang Chen   +5 more
semanticscholar   +1 more source

Novel heterocyclic quinoline derivatives as green environmental corrosion inhibitors for carbon steel in HCl solution: experimental and theoretical investigation

Journal of Adhesion Science and Technology, 2021
The corrosion behavior of carbon steel in 1 M HCl solution in the absence and presence of newly synthesized 4,4′-Oxybis{N-[ E -quinoline-3-ylmethylidene]aniline} 4,4′-thio bis{N-[ E -quinoline-3-ylmethylidene]aniline} and 44,4′-Methylenebis{N-[ E ...
D. Daoud, H. Hamani, T. Douadi
semanticscholar   +1 more source

Updates on the versatile quinoline heterocycles as anticancer agents

Physical Sciences Reviews, 2021
Quinoline motifs have befallen significant molecules due to their assortment of interest in medicine, chemical synthesis, coordination chemistry, also in the field of applied chemistry.
Basavarajaiah Suliphuldevara Matada, N. Yernale, Jeelan Basha N   +2 more
semanticscholar   +1 more source

Quinoline-Based Antifungals

Current Medicinal Chemistry, 2010
Although the assortment of antifungal drugs is broad, the most commonly used agents have major drawbacks. Toxicity, serious side effects or the emergence of drug resistance are amongst them. New drugs and drug candidates under clinical trials do not guarantee better pharmacological parameters. These new medicines may appear effective; however; they may
R, Musiol, M, Serda, S, Hensel-Bielowka, J, Polanski   +3 more
openaire   +2 more sources