Results 11 to 20 of about 103,486 (339)
Quinolones are the second most common antibiotic class associated with drug-induced allergic reactions, but data on quinolone allergy are scarce. This review article discusses the available evidence on quinolone allergy, including prevalence, risk ...
Edoabasi U. McGee+5 more
semanticscholar +4 more sources
The quinolone antibiotics arose in the early 1960s, with the first examples possessing a narrow-spectrum activity with unfavorable pharmacokinetic properties.
Thu D M Pham, Z. Ziora, M. Blaskovich
semanticscholar +5 more sources
Quinolone Antibiotics: Resistance and Therapy
The clinical application of quinolone antibiotics is particularly extensive. In addition to their high efficiency in infectious diseases, the treatment process brings multiple hidden dangers or side effects.
Kai Tang, Heng Zhao
semanticscholar +1 more source
Quinolone: a versatile therapeutic compound class
The discovery of nalidixic acid is one pinnacle in medicinal chemistry, which opened a new area of research that has led to the discovery of several life-saving antimicrobial agents (generally referred to as fluoroquinolones) for over decades.
Phelelisiwe S. Dube+2 more
semanticscholar +1 more source
Background and Aim Recently, the extensive use of quinolones led to increased resistance to these antimicrobial agents, with different rates according to the organism and the geographical region. The aim of this study was to detect the resistance rate of
S. Kareem+11 more
semanticscholar +1 more source
Quinolone resistance in bacterial pathogens has primarily been associated with mutations in the quinolone resistance-determining regions (QRDRs) of bacterial type-II topoisomerases, which are DNA gyrase and topoisomerase IV. Depending on the position and
A. Shaheen+6 more
semanticscholar +1 more source
R Gold
openalex +5 more sources
Quinolone and Organophosphorus Insecticide Residues in Bivalves and Their Associated Risks in Taiwan
Bivalves, such as freshwater clams (Corbicula fluminea) and hard clams (Meretrix lusoria), are the most extensive and widely grown shellfish in land-based ponds in Taiwan.
Ching-Feng Wu+10 more
doaj +1 more source
The emergence of bacteria that are resistant to antibiotics is common in areas where antibiotics are used widely. The current standard procedure for detecting bacterial drug resistance is based on bacterial growth under antibiotic treatments.
Mitsuko Hayashi-Nishino+18 more
doaj +1 more source
Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]
Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael+8 more
core +3 more sources