Results 41 to 50 of about 103,486 (339)
Extended-spectrum β-lactamases, transferable quinolone resistance, and virulotyping in extra-intestinal E. coli in Uruguay [PDF]
, 2016 Introduction: To characterize extended-spectrum β-lactamases (ESBLs) and plasmid-mediated quinolone resistance (PMQR) genes in Escherichia coli isolates obtained from extra-intestinal samples in three Uruguayan hospitals.
Aguerrebere, Paula +10 more
core +2 more sources
Antibiotics, 2022 Antimicrobial resistance is a major public health issue caused by antibiotic overuse and misuse. Antimicrobial stewardship (AMS) has been increasingly endorsed worldwide, but its effect has been studied scarcely in urologic settings. A before-after study
Oana Joean +8 more
doaj +1 more source
Journal of Medical Microbiology, 2019 Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors such as lectin A, pyocyanin, elastase and rhamnolipids.
Selene García-Reyes +2 more
semanticscholar +1 more source
The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa [PDF]
, 2006 Certain members of the fluorescent pseudomonads produce and secrete phenazines. These heterocyclic, redox-active compounds are toxic to competing organisms, and the cause of these antibiotic effects has been the focus of intense research efforts.
Dietrich, Lars E. P. +4 more
core +1 more source
Transferable Mechanisms of Quinolone Resistance from 1998 Onward
Clinical Microbiology Reviews, 2019 While the description of resistance to quinolones is almost as old as these antimicrobial agents themselves, transferable mechanisms of quinolone resistance (TMQR) remained absent from the scenario for more than 36 years, appearing first as sporadic ...
J. Ruiz
semanticscholar +1 more source
Development of the quinolones [PDF]
Journal of Antimicrobial Chemotherapy, 2003 Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and scientific interest. Nalidixic acid, the first quinolone to be developed, was obtained as an impurity during the manufacture of quinine.
Alasdair P. MacGowan +1 more
openaire +3 more sources
Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions
Angewandte Chemie, EarlyView.In this study, we capitalize on the versatility offered by genetic code expansion to develop a proficient photoenzyme for [2 + 2]‐cycloadditions that is enantiocomplementary to our recently developed photoenzyme EnT1.3. By repositioning the genetically programmed benzophenone photosensitizer and subsequent directed evolution, we have developed an ...
Chuanjie Sun +9 more
wiley +2 more sources
Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]
, 2012 The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Bousquet-Mélou, Alain +7 more
core +3 more sources
Antibiotic resistance in the environment, with particular reference to MRSA [PDF]
, 2008 The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
Aarestrup +171 more
core +1 more source
Meningococcal Quinolone Resistance Originated from Several Commensal Neisseria Species
Antimicrobial Agents and Chemotherapy, 2019 Quinolone resistance is increasing in Neisseria meningitidis, with its prevalence in China being high (>70%), but its origin remains unknown. The aim of this study was to investigate the donors of mutation-harboring gyrA alleles in N. meningitidis.
Mingliang Chen +3 more
semanticscholar +1 more source