Results 71 to 80 of about 136,091 (317)
Enzymatic one-step ring contraction for quinolone biosynthesis. [PDF]
, 2018 The 6,6-quinolone scaffolds on which viridicatin-type fungal alkaloids are built are frequently found in metabolites that display useful biological activities.
Champagne, Pier Alexandre +7 more
core
BMEMat, EarlyView.This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang +11 more
wiley +1 more source
Antibiotics, 2021 Antimicrobial resistance to quinolones, which constitutes a threat to public health, has been increasing worldwide. In this study, we investigated the prevalence of quinolone-resistant determinants in Escherichia coli not susceptible to quinolones and ...
Lawrence Belotindos +8 more
doaj +1 more source
Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]
, 2005 Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N +4 more
core +1 more source
Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms. [PDF]
, 2020 Staphylococcus aureus biofilms are a significant problem in health care settings, partly due to the presence of a nondividing, antibiotic-tolerant subpopulation. Here we evaluated treatment of S.
Allan, RN +7 more
core +2 more sources
A Riboflavin‐Derived Flavinium Salt Mediates Chemoselective Methylation Reactions
Chemistry – A European Journal, EarlyView.A two‐component methylation protocol was developed, where the active flavin mediator can be recycled in a single step. Crystallographic data and NMR spectroscopy support the mechanistic proposal, while chemoselective methylation was observed for a broad range of biologically relevant substrates. ABSTRACT Selective methylation is among the most relevant
Tim Langschwager +3 more
wiley +1 more source
The Pan African Medical Journal, 2015 INTRODUCTION: it is estimated that 150 million urinary tract infections (UTIs) occur yearly worldwide, resulting in more than 6 billion dollar in direct healthcare cost.
Emilia Enjema Lyonga +9 more
doaj +1 more source
Lanthanum triflate triggered synthesis of tetrahydroquinazolinone derivatives of N-allyl quinolone and their biological assessment [PDF]
Journal of the Serbian Chemical Society, 2012 A series of 24 derivatives of tetrahydroquinazolinone has been synthesized by one-pot cyclocondensation reaction of N-allyl quinolones, cyclic β-diketones and (thio)urea/N-phenylthiourea in presence of lanthanum triflate catalyst.
Jardosh Hardik H., Patel Manish P.
doaj +1 more source
Molecules, 2023 The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria, Plasmodium spp. In this study, we show that aurachin D inhibits other parasitic protozoa as well.
Sebastian Kruth +7 more
doaj +1 more source
Effect of pH on ciprofloxacin ozonation in hospital WWTP effluent [PDF]
, 2009 A bubble column was used for ozonation of the quinolone antibiotic ciprofloxacin and the effect of pH was tested. Degradation at pH 7 increased the ciprofloxacin half life time to 29.1 min compared to pH 3 (26.8 min) and pH 10 (18.7 min), possibly due to
De Wispelaere, Patrick +4 more
core